RPL13 and MAPKAPK5

Number of citations of the paper that reports this interaction (PMID 21900206)
27

Data Source:
BioGRID (two hybrid)

		RPL13	MAPKAPK5
Gene Name		ribosomal protein L13	mitogen-activated protein kinase-activated protein kinase 5
Image			No pdb structure
Gene Ontology Annotations	Cellular Component	Nucleus Nucleolus Cytoplasm Cytosol Membrane Cytosolic Large Ribosomal Subunit Cytosolic Ribosome	Nucleoplasm Cytoplasm
	Molecular Function	RNA Binding Structural Constituent Of Ribosome Protein Binding Poly(A) RNA Binding	P53 Binding Protein Serine/threonine Kinase Activity MAP Kinase Kinase Activity Protein Binding ATP Binding Mitogen-activated Protein Kinase Binding
	Biological Process	Nuclear-transcribed MRNA Catabolic Process, Nonsense-mediated Decay Translation Translational Initiation Translational Elongation Translational Termination SRP-dependent Cotranslational Protein Targeting To Membrane Gene Expression Viral Process Viral Life Cycle Viral Transcription Cellular Protein Metabolic Process	MAPK Cascade Activation Of MAPK Activity Regulation Of Translation Signal Transduction Ras Protein Signal Transduction Negative Regulation Of TOR Signaling Protein Autophosphorylation Stress-induced Premature Senescence
Pathways		Nonsense-Mediated Decay (NMD) Translation SRP-dependent cotranslational protein targeting to membrane Eukaryotic Translation Termination Peptide chain elongation Influenza Infection Viral mRNA Translation L13a-mediated translational silencing of Ceruloplasmin expression Influenza Life Cycle Nonsense Mediated Decay (NMD) enhanced by the Exon Junction Complex (EJC) Influenza Viral RNA Transcription and Replication GTP hydrolysis and joining of the 60S ribosomal subunit Eukaryotic Translation Initiation Formation of a pool of free 40S subunits Eukaryotic Translation Elongation Cap-dependent Translation Initiation Nonsense Mediated Decay (NMD) independent of the Exon Junction Complex (EJC)	Oxidative Stress Induced Senescence Cellular Senescence
Drugs
Diseases
GWAS
Protein-Protein Interactions		16 interactors: ANXA7 CEP70 CSNK2A1 CSNK2B DAXX ILK IPO5 MAP2K3 MAPKAPK5 RAD21 RELA SMN1 SPP1 TERF2 TK1 UPF2	28 interactors: ATF2 CDCA8 EEF2K EIF4E EIF4EBP1 GYS1 HSPB1 HSPB2 JUN LSR MAPK1 MAPK11 MAPK12 MAPK13 MAPK14 MAPK4 MAPK6 MAPK9 MBP MYH11 PLA2G4A RPL13 SRPK1 SRPK2 TAB1 TP53 ZNF282 ZNF576
Entrez ID		6137	8550
HPRD ID		06428	09467
Ensembl ID		ENSG00000167526	ENSG00000089022
Uniprot IDs		A8K4C8 P26373	Q8IW41
PDB IDs		3J3B
Enriched GO Terms of Interacting Partners?		Positive Regulation Of Protein Metabolic Process Positive Regulation Of Signal Transduction Positive Regulation Of MAP Kinase Activity Cell Cycle Cell Aging Positive Regulation Of Protein Serine/threonine Kinase Activity Regulation Of MAP Kinase Activity Aging Positive Regulation Of Protein Phosphorylation Regulation Of Protein Kinase Activity Mitotic Cell Cycle Phosphorylation Activation Of MAPK Activity Response To Stress Regulation Of Kinase Activity Developmental Process Positive Regulation Of Intracellular Signal Transduction Liver Development Response To Stimulus Protein Localization To Chromosome Positive Regulation Of MAPK Cascade Cellular Senescence Positive Regulation Of Phosphorylation Positive Regulation Of Protein Kinase Activity Positive Regulation Of Protein Modification Process Positive Regulation Of Kinase Activity Regulation Of Protein Metabolic Process Cellular Response To Stress Anatomical Structure Development Positive Regulation Of Transferase Activity MAPK Cascade Cell Cycle Process Regulation Of Catalytic Activity Regulation Of Protein Phosphorylation Toll-like Receptor 5 Signaling Pathway Positive Regulation Of Cellular Protein Metabolic Process Toll-like Receptor 10 Signaling Pathway Regulation Of MAPK Cascade Toll-like Receptor TLR6:TLR2 Signaling Pathway Toll-like Receptor TLR1:TLR2 Signaling Pathway Cellular Response To Stimulus Negative Regulation Of Collateral Sprouting Of Intact Axon In Response To Injury Fetal Process Involved In Parturition Acetaldehyde Metabolic Process Positive Regulation Of Metabolic Process Activation Of Protein Kinase Activity Toll-like Receptor 2 Signaling Pathway Toll-like Receptor 9 Signaling Pathway Positive Regulation Of Cellular Metabolic Process Signal Transduction By Phosphorylation	MAPK Cascade Signal Transduction By Phosphorylation Toll-like Receptor 5 Signaling Pathway Toll-like Receptor 10 Signaling Pathway Toll-like Receptor TLR6:TLR2 Signaling Pathway Toll-like Receptor TLR1:TLR2 Signaling Pathway Toll-like Receptor 2 Signaling Pathway Toll-like Receptor 9 Signaling Pathway TRIF-dependent Toll-like Receptor Signaling Pathway MyD88-independent Toll-like Receptor Signaling Pathway Toll-like Receptor 3 Signaling Pathway MyD88-dependent Toll-like Receptor Signaling Pathway Toll-like Receptor 4 Signaling Pathway Enzyme Linked Receptor Protein Signaling Pathway Intracellular Signal Transduction Toll-like Receptor Signaling Pathway Stress-activated MAPK Cascade Stress-activated Protein Kinase Signaling Cascade Pattern Recognition Receptor Signaling Pathway Innate Immune Response-activating Signal Transduction Activation Of Innate Immune Response Cellular Response To Growth Factor Stimulus Response To Growth Factor Positive Regulation Of Innate Immune Response Vascular Endothelial Growth Factor Receptor Signaling Pathway Transmembrane Receptor Protein Tyrosine Kinase Signaling Pathway Phosphorylation Regulation Of Innate Immune Response Response To Organic Substance Response To Stress Gene Expression Cellular Response To Organic Substance Regulation Of Sequence-specific DNA Binding Transcription Factor Activity Immune Response Protein Phosphorylation Signaling Phosphate-containing Compound Metabolic Process Cell Cycle Cell Communication Ras Protein Signal Transduction Innate Immune Response Signal Transduction Mitochondrion Organization Regulation Of Cellular Protein Metabolic Process Immune Response-regulating Signaling Pathway Apoptotic Mitochondrial Changes Defense Response Response To Toxic Substance Cellular Response To Stimulus Response To Stimulus
Tagcloud ?		30s 5a 60s amongst atub bestkeeper cyp ef foundation gapdh genorm ginseng housekeeping iia ingredients medicines normalization normfinder optimum panax popular qcr qrt ranked reference rps20 sar1 stems transcriptomics	acids amino blot designated encodes erk gst homology identities jnk jun kinase light mitogen myosin northern novel nucleotide p38 phosphorylate phosphorylated recombinant sequence shares substrate wide
Tagcloud (Difference) ?		30s 5a 60s amongst atub bestkeeper cyp ef foundation gapdh genorm ginseng housekeeping iia ingredients medicines normalization normfinder optimum panax popular qcr qrt ranked reference rps20 sar1 stems transcriptomics	acids amino blot designated encodes erk gst homology identities jnk jun kinase light mitogen myosin northern novel nucleotide p38 phosphorylate phosphorylated recombinant sequence shares substrate wide
Tagcloud (Intersection) ?