RFX1 and NFIC

Number of citations of the paper that reports this interaction (PMID 12624117)
3

Data Source:
BioGRID (affinity chromatography technology)
HPRD (in vivo, in vitro)

		RFX1	NFIC
Gene Name		regulatory factor X, 1 (influences HLA class II expression)	nuclear factor I/C (CCAAT-binding transcription factor)
Image			No pdb structure
Gene Ontology Annotations	Cellular Component	Nucleus Nucleoplasm Intracellular Membrane-bounded Organelle	Nucleus Nucleoplasm Nucleolus
	Molecular Function	RNA Polymerase II Core Promoter Proximal Region Sequence-specific DNA Binding RNA Polymerase II Distal Enhancer Sequence-specific DNA Binding Transcription Factor Activity Protein Binding	RNA Polymerase II Core Promoter Proximal Region Sequence-specific DNA Binding Sequence-specific DNA Binding RNA Polymerase II Transcription Factor Activity RNA Polymerase II Core Promoter Proximal Region Sequence-specific DNA Binding Transcription Factor Activity Involved In Positive Regulation Of Transcription Double-stranded DNA Binding Sequence-specific DNA Binding Transcription Factor Activity
	Biological Process	Regulation Of Transcription From RNA Polymerase II Promoter Transcription From RNA Polymerase II Promoter Immune Response	Negative Regulation Of Transcription From RNA Polymerase II Promoter DNA Replication Transcription From RNA Polymerase II Promoter Odontogenesis Of Dentin-containing Tooth Positive Regulation Of Transcription From RNA Polymerase II Promoter
Pathways			RNA Polymerase III Transcription RNA Polymerase III Transcription Termination RNA Polymerase I, RNA Polymerase III, and Mitochondrial Transcription RNA Polymerase III Abortive And Retractive Initiation
Drugs
Diseases
GWAS			Height ( 20881960)
Protein-Protein Interactions		14 interactors: ABL1 ADD1 HIVEP2 HMGB1 MAGED1 NFIB NFIC NFIX RFX2 RFX3 SMAD1 SMAD4 SMAD9 TADA3	10 interactors: CREBBP GLRX LLPH NFIB RFX1 TKTL2 TLX1 TPD52L3 ZCCHC14 ZKSCAN7
Entrez ID		5989	4782
HPRD ID		02476	09009
Ensembl ID		ENSG00000132005	ENSG00000141905
Uniprot IDs		P22670	B7Z4T6 P08651
PDB IDs		1DP7
Enriched GO Terms of Interacting Partners?		Regulation Of Transcription From RNA Polymerase II Promoter Positive Regulation Of Cellular Metabolic Process Positive Regulation Of Transcription, DNA-templated Regulation Of Nitrogen Compound Metabolic Process Positive Regulation Of Macromolecule Biosynthetic Process Positive Regulation Of Gene Expression Positive Regulation Of Cellular Biosynthetic Process Regulation Of Transcription, DNA-templated Regulation Of Nucleic Acid-templated Transcription Regulation Of RNA Biosynthetic Process Regulation Of RNA Metabolic Process Positive Regulation Of Metabolic Process Regulation Of Gene Expression Hindbrain Development Transcription, DNA-templated RNA Biosynthetic Process Regulation Of Metabolic Process Nucleobase-containing Compound Metabolic Process Negative Regulation Of Gene Expression Heterocycle Metabolic Process Cellular Aromatic Compound Metabolic Process Cellular Nitrogen Compound Metabolic Process Positive Regulation Of Transcription From RNA Polymerase II Promoter Negative Regulation Of Transcription, DNA-templated RNA Metabolic Process Negative Regulation Of Nucleic Acid-templated Transcription Nitrogen Compound Metabolic Process Negative Regulation Of RNA Biosynthetic Process Anatomical Structure Morphogenesis Gene Expression Cellular Macromolecule Biosynthetic Process Macromolecule Biosynthetic Process Negative Regulation Of Biosynthetic Process Transcription From RNA Polymerase II Promoter Negative Regulation Of Cellular Metabolic Process Organ Development BMP Signaling Pathway Regulation Of Binding System Development SMAD Protein Complex Assembly Ureteric Bud Development Mesonephric Tubule Development Mesonephric Epithelium Development Multicellular Organismal Development Mesonephros Development Biosynthetic Process Brain Development Negative Regulation Of Transcription From RNA Polymerase II Promoter Anatomical Structure Development Transforming Growth Factor Beta Receptor Signaling Pathway	Negative Regulation Of Epithelial Cell Proliferation Involved In Lung Morphogenesis Protein Deglutathionylation Lung Ciliated Cell Differentiation Principal Sensory Nucleus Of Trigeminal Nerve Development Negative Regulation Of Mesenchymal Cell Proliferation Involved In Lung Development N-terminal Peptidyl-lysine Acetylation Regulation Of Transcription From RNA Polymerase II Promoter Transcription From RNA Polymerase II Promoter Germ-line Stem Cell Maintenance Negative Regulation Of Mesenchymal Cell Proliferation Regulation Of Epithelial Cell Proliferation Involved In Lung Morphogenesis Type II Pneumocyte Differentiation Clara Cell Differentiation Transcription, DNA-templated Positive Regulation Of Transcription From RNA Polymerase II Promoter Anterior Commissure Morphogenesis RNA Biosynthetic Process Regulation Of Transcription, DNA-templated Regulation Of Nucleic Acid-templated Transcription Regulation Of RNA Biosynthetic Process Regulation Of RNA Metabolic Process N-terminal Protein Amino Acid Acetylation Positive Regulation Of Sodium Ion Transmembrane Transporter Activity Nucleobase-containing Compound Metabolic Process Lung Secretory Cell Differentiation Commissural Neuron Axon Guidance Positive Regulation Of Sodium Ion Transmembrane Transport Nucleobase-containing Small Molecule Interconversion Heterocycle Metabolic Process Cellular Aromatic Compound Metabolic Process Positive Regulation Of Transcription, DNA-templated Regulation Of Gene Expression Regulation Of Nitrogen Compound Metabolic Process Type I Pneumocyte Differentiation Cellular Nitrogen Compound Metabolic Process Positive Regulation Of Macromolecule Biosynthetic Process Regulation Of Transcription From RNA Polymerase II Promoter In Response To Hypoxia Positive Regulation Of Gene Expression N-terminal Protein Amino Acid Modification RNA Metabolic Process Positive Regulation Of Cellular Biosynthetic Process Regulation Of Sodium Ion Transmembrane Transporter Activity Regulation Of Cellular Response To Heat Nitrogen Compound Metabolic Process Negative Regulation Of Stem Cell Proliferation Gene Expression Regulation Of Sodium Ion Transmembrane Transport Positive Regulation Of Sodium Ion Transport Central Nervous System Projection Neuron Axonogenesis Cellular Macromolecule Biosynthetic Process
Tagcloud ?		243r abrogated adenovirus antagonizes cooperative disrupt e1a eh1 electrophoretic exerted implying kannabiran labrie mathews morris mutational nucleic oncoprotein p107 pcna proliferating relieves repress res retain suggestive transactivating unable virol	advance avian bcl2 bcl2l1 ccaat cebpb construction coordinated cytoscape datasets differentially downloaded encyclopedia enrichment genomes gse14359 homolog il6 interpret kyoto omnibus ontology osteosarcoma pivotal rara rel rela reticuloendotheliosis tp53
Tagcloud (Difference) ?		243r abrogated adenovirus antagonizes cooperative disrupt e1a eh1 electrophoretic exerted implying kannabiran labrie mathews morris mutational nucleic oncoprotein p107 pcna proliferating relieves repress res retain suggestive transactivating unable virol	advance avian bcl2 bcl2l1 ccaat cebpb construction coordinated cytoscape datasets differentially downloaded encyclopedia enrichment genomes gse14359 homolog il6 interpret kyoto omnibus ontology osteosarcoma pivotal rara rel rela reticuloendotheliosis tp53
Tagcloud (Intersection) ?