NFIC and NFIB

Number of citations of the paper that reports this interaction (PMID 9099724)
9

Data Source:
HPRD (in vitro)

		NFIC	NFIB
Gene Name		nuclear factor I/C (CCAAT-binding transcription factor)	nuclear factor I/B
Image		No pdb structure	No pdb structure
Gene Ontology Annotations	Cellular Component	Nucleus Nucleoplasm Nucleolus	Nucleus Nucleoplasm Nucleolus Cerebellar Mossy Fiber
	Molecular Function	RNA Polymerase II Core Promoter Proximal Region Sequence-specific DNA Binding Sequence-specific DNA Binding RNA Polymerase II Transcription Factor Activity RNA Polymerase II Core Promoter Proximal Region Sequence-specific DNA Binding Transcription Factor Activity Involved In Positive Regulation Of Transcription Double-stranded DNA Binding Sequence-specific DNA Binding Transcription Factor Activity	RNA Polymerase II Core Promoter Proximal Region Sequence-specific DNA Binding Sequence-specific DNA Binding RNA Polymerase II Transcription Factor Activity RNA Polymerase II Core Promoter Proximal Region Sequence-specific DNA Binding Transcription Factor Activity Involved In Positive Regulation Of Transcription RNA Polymerase II Transcription Corepressor Activity DNA Binding Double-stranded DNA Binding
	Biological Process	Negative Regulation Of Transcription From RNA Polymerase II Promoter DNA Replication Transcription From RNA Polymerase II Promoter Odontogenesis Of Dentin-containing Tooth Positive Regulation Of Transcription From RNA Polymerase II Promoter	Negative Regulation Of Transcription From RNA Polymerase II Promoter Chondrocyte Differentiation DNA Replication Transcription From RNA Polymerase II Promoter Glial Cell Differentiation Principal Sensory Nucleus Of Trigeminal Nerve Development Anterior Commissure Morphogenesis Hindbrain Development Negative Regulation Of DNA Binding Positive Regulation Of Transcription From RNA Polymerase II Promoter Clara Cell Differentiation Type I Pneumocyte Differentiation Type II Pneumocyte Differentiation Lung Ciliated Cell Differentiation Commissural Neuron Axon Guidance Negative Regulation Of Mesenchymal Cell Proliferation Involved In Lung Development Negative Regulation Of Epithelial Cell Proliferation Involved In Lung Morphogenesis
Pathways		RNA Polymerase III Transcription RNA Polymerase III Transcription Termination RNA Polymerase I, RNA Polymerase III, and Mitochondrial Transcription RNA Polymerase III Abortive And Retractive Initiation	RNA Polymerase III Transcription RNA Polymerase III Transcription Termination RNA Polymerase I, RNA Polymerase III, and Mitochondrial Transcription RNA Polymerase III Abortive And Retractive Initiation
Drugs
Diseases
GWAS		Height ( 20881960)	Alzheimer's disease biomarkers ( 23419831)
Protein-Protein Interactions		10 interactors: CREBBP GLRX LLPH NFIB RFX1 TKTL2 TLX1 TPD52L3 ZCCHC14 ZKSCAN7	3 interactors: NFIC NFIX RFX1
Entrez ID		4782	4781
HPRD ID		09009	09008
Ensembl ID		ENSG00000141905	ENSG00000147862
Uniprot IDs		B7Z4T6 P08651	O00712 Q5VW26 Q5VW27 Q5VW28 Q5VW30
PDB IDs
Enriched GO Terms of Interacting Partners?		Negative Regulation Of Epithelial Cell Proliferation Involved In Lung Morphogenesis Protein Deglutathionylation Lung Ciliated Cell Differentiation Principal Sensory Nucleus Of Trigeminal Nerve Development Negative Regulation Of Mesenchymal Cell Proliferation Involved In Lung Development N-terminal Peptidyl-lysine Acetylation Regulation Of Transcription From RNA Polymerase II Promoter Transcription From RNA Polymerase II Promoter Germ-line Stem Cell Maintenance Negative Regulation Of Mesenchymal Cell Proliferation Regulation Of Epithelial Cell Proliferation Involved In Lung Morphogenesis Type II Pneumocyte Differentiation Clara Cell Differentiation Transcription, DNA-templated Positive Regulation Of Transcription From RNA Polymerase II Promoter Anterior Commissure Morphogenesis RNA Biosynthetic Process Regulation Of Transcription, DNA-templated Regulation Of Nucleic Acid-templated Transcription Regulation Of RNA Biosynthetic Process Regulation Of RNA Metabolic Process N-terminal Protein Amino Acid Acetylation Positive Regulation Of Sodium Ion Transmembrane Transporter Activity Nucleobase-containing Compound Metabolic Process Lung Secretory Cell Differentiation Commissural Neuron Axon Guidance Positive Regulation Of Sodium Ion Transmembrane Transport Nucleobase-containing Small Molecule Interconversion Heterocycle Metabolic Process Cellular Aromatic Compound Metabolic Process Positive Regulation Of Transcription, DNA-templated Regulation Of Gene Expression Regulation Of Nitrogen Compound Metabolic Process Type I Pneumocyte Differentiation Cellular Nitrogen Compound Metabolic Process Positive Regulation Of Macromolecule Biosynthetic Process Regulation Of Transcription From RNA Polymerase II Promoter In Response To Hypoxia Positive Regulation Of Gene Expression N-terminal Protein Amino Acid Modification RNA Metabolic Process Positive Regulation Of Cellular Biosynthetic Process Regulation Of Sodium Ion Transmembrane Transporter Activity Regulation Of Cellular Response To Heat Nitrogen Compound Metabolic Process Negative Regulation Of Stem Cell Proliferation Gene Expression Regulation Of Sodium Ion Transmembrane Transport Positive Regulation Of Sodium Ion Transport Central Nervous System Projection Neuron Axonogenesis Cellular Macromolecule Biosynthetic Process	Transcription From RNA Polymerase II Promoter DNA Replication Regulation Of Transcription From RNA Polymerase II Promoter Transcription, DNA-templated RNA Biosynthetic Process Cerebellar Granule Cell Differentiation Cerebellar Granular Layer Morphogenesis RNA Metabolic Process Cerebellar Granular Layer Development Negative Regulation Of Transcription From RNA Polymerase II Promoter Gene Expression Cerebellar Cortex Formation Cellular Macromolecule Biosynthetic Process Cell Differentiation In Hindbrain Macromolecule Biosynthetic Process Cerebellar Purkinje Cell Layer Development Astrocyte Differentiation Cerebellar Cortex Morphogenesis Positive Regulation Of Transcription From RNA Polymerase II Promoter DNA Metabolic Process Regulation Of Transcription, DNA-templated Negative Regulation Of Transcription, DNA-templated Cerebellum Morphogenesis Regulation Of Nucleic Acid-templated Transcription Regulation Of RNA Biosynthetic Process Negative Regulation Of Nucleic Acid-templated Transcription Hindbrain Morphogenesis Negative Regulation Of RNA Biosynthetic Process Regulation Of RNA Metabolic Process Nucleobase-containing Compound Metabolic Process Cerebellar Cortex Development Heterocycle Metabolic Process Cellular Aromatic Compound Metabolic Process Biosynthetic Process Regulation Of Gene Expression Negative Regulation Of Gene Expression Positive Regulation Of Transcription, DNA-templated Regulation Of Nitrogen Compound Metabolic Process Negative Regulation Of Biosynthetic Process Cellular Nitrogen Compound Metabolic Process Positive Regulation Of Macromolecule Biosynthetic Process Positive Regulation Of Gene Expression Nitrogen Compound Metabolic Process Positive Regulation Of Cellular Biosynthetic Process Odontogenesis Of Dentin-containing Tooth Cerebellum Development Metencephalon Development Odontogenesis Hindbrain Development Negative Regulation Of Cellular Metabolic Process
Tagcloud ?		advance avian bcl2 bcl2l1 ccaat cebpb construction coordinated cytoscape datasets differentially downloaded encyclopedia enrichment genomes gse14359 homolog il6 interpret kyoto omnibus ontology osteosarcoma pivotal rara rel rela reticuloendotheliosis tp53	abolished aimed alteration caused colony direct dyrk1a explore finding fluorescent hcc hepatocellular hepg2 mir modulated nfat oncogene overexpression p53 propose regulated reporter suggests suppresses syndrome target targeting tumorigenesis wild
Tagcloud (Difference) ?		advance avian bcl2 bcl2l1 ccaat cebpb construction coordinated cytoscape datasets differentially downloaded encyclopedia enrichment genomes gse14359 homolog il6 interpret kyoto omnibus ontology osteosarcoma pivotal rara rel rela reticuloendotheliosis tp53	abolished aimed alteration caused colony direct dyrk1a explore finding fluorescent hcc hepatocellular hepg2 mir modulated nfat oncogene overexpression p53 propose regulated reporter suggests suppresses syndrome target targeting tumorigenesis wild
Tagcloud (Intersection) ?