RBL2 and BRF2

Number of citations of the paper that reports this interaction (PMID 10330166)
17

Data Source:
HPRD (in vivo)

		RBL2	BRF2
Gene Name		retinoblastoma-like 2	BRF2, RNA polymerase III transcription initiation factor 50 kDa subunit
Image		No pdb structure	No pdb structure
Gene Ontology Annotations	Cellular Component	Nucleus Nucleoplasm Transcription Factor Complex Nucleolus Cytoplasm Extracellular Vesicular Exosome	Nucleoplasm
	Molecular Function	DNA Binding Protein Binding	Zinc Ion Binding
	Biological Process	Mitotic Cell Cycle Transcription, DNA-templated Regulation Of Transcription From RNA Polymerase II Promoter Chromatin Modification Regulation Of Lipid Kinase Activity Regulation Of Cell Cycle	DNA-templated Transcription, Initiation Regulation Of Transcription, DNA-templated Transcription From RNA Polymerase III Promoter Gene Expression
Pathways		Cyclin D associated events in G1 G1 Phase G0 and Early G1 Mitotic G1-G1/S phases Cell Cycle, Mitotic	RNA Polymerase III Transcription RNA Polymerase III Transcription Initiation RNA Polymerase III Transcription Initiation From Type 3 Promoter RNA Polymerase I, RNA Polymerase III, and Mitochondrial Transcription RNA Polymerase III Abortive And Retractive Initiation
Drugs
Diseases
GWAS
Protein-Protein Interactions		42 interactors: BRCA1 BRF1 BRF2 CCNA1 CCNA2 CCND1 CCND3 CCNE1 CDK2 CDK4 CDK6 CREG1 DCTN1 DGKZ E2F4 E2F5 EZH2 GRAMD4 HBP1 HDAC1 ID2 LBX1 LDHC MCM7 MNDA PCBD1 PHB PPP2CA RAF1 RBBP8 RBBP9 RINT1 SKP2 SMARCA4 SNW1 SUV39H1 SUV420H2 TAF1 TOP1 UBTF USP4 XBP1	3 interactors: RBL2 SNAPC4 TBP
Entrez ID		5934	55290
HPRD ID		01576	06115
Ensembl ID		ENSG00000103479
Uniprot IDs		Q08999 Q8NE70	Q9HAW0
PDB IDs
Enriched GO Terms of Interacting Partners?		Cell Cycle Mitotic Cell Cycle Phase Transition Cell Cycle Phase Transition G1/S Transition Of Mitotic Cell Cycle Mitotic Cell Cycle Regulation Of Cell Cycle Regulation Of Gene Expression Cell Cycle Process Regulation Of Metabolic Process Mitotic Cell Cycle Process Regulation Of Nitrogen Compound Metabolic Process Nucleobase-containing Compound Metabolic Process Positive Regulation Of Cellular Metabolic Process Regulation Of Transcription, DNA-templated Cellular Macromolecule Biosynthetic Process Regulation Of Nucleic Acid-templated Transcription Regulation Of RNA Biosynthetic Process Heterocycle Metabolic Process Cellular Aromatic Compound Metabolic Process Macromolecule Biosynthetic Process Regulation Of RNA Metabolic Process Positive Regulation Of Metabolic Process Cellular Nitrogen Compound Metabolic Process Transcription, DNA-templated RNA Biosynthetic Process Cell Division Regulation Of Cell Proliferation Regulation Of Mitotic Cell Cycle Phase Transition Regulation Of Cell Cycle Phase Transition Negative Regulation Of Cell Cycle RNA Metabolic Process Positive Regulation Of Gene Expression Nitrogen Compound Metabolic Process Regulation Of Transcription From RNA Polymerase II Promoter Positive Regulation Of Cellular Biosynthetic Process Regulation Of Cell Cycle Process Biosynthetic Process Gene Expression Positive Regulation Of Macromolecule Biosynthetic Process Regulation Of Mitotic Cell Cycle Chromatin Organization Positive Regulation Of Transcription, DNA-templated Regulation Of Cellular Process DNA-templated Transcription, Initiation Cellular Metabolic Process Organelle Organization Regulation Of Cellular Protein Metabolic Process Chromosome Organization Cellular Response To Stress Regulation Of Protein Kinase Activity	Transcription From RNA Polymerase III Promoter SnRNA Transcription From RNA Polymerase III Promoter SnRNA Transcription From RNA Polymerase II Promoter Transcription, DNA-templated RNA Biosynthetic Process SnRNA Transcription Chromatin Silencing At RDNA RNA Metabolic Process Gene Expression Termination Of RNA Polymerase I Transcription Transcription Elongation From RNA Polymerase I Promoter Transcription Initiation From RNA Polymerase I Promoter Cellular Macromolecule Biosynthetic Process Macromolecule Biosynthetic Process Transcription From RNA Polymerase II Promoter Transcription From RNA Polymerase I Promoter Chromatin Silencing SnRNA Metabolic Process Regulation Of Transcription, DNA-templated Regulation Of Nucleic Acid-templated Transcription Regulation Of RNA Biosynthetic Process Regulation Of RNA Metabolic Process Nucleobase-containing Compound Metabolic Process Regulation Of Lipid Kinase Activity Transcription Elongation From RNA Polymerase II Promoter Heterocycle Metabolic Process Cellular Aromatic Compound Metabolic Process Biosynthetic Process Regulation Of Gene Expression DNA-templated Transcription, Termination Regulation Of Nitrogen Compound Metabolic Process Negative Regulation Of Gene Expression, Epigenetic Cellular Nitrogen Compound Metabolic Process DNA-templated Transcription, Elongation Nitrogen Compound Metabolic Process Gene Silencing Transcription Initiation From RNA Polymerase II Promoter
Tagcloud ?		arginine bcl3 casp10 dap1 derepression epigenetic epigenetically governs hdac1 hodgkin hoxa5 hrk indirectly lymphoma master methyltransferase offer p52 polycomb prc2 prmt5 rb1 reactivation repression repressor retinoblastoma tp53k372 trigger turn	accomplished bmmc bmmcs brf1 connected cytokine deficient dependence dispensable exerted influencing initially lps lysates mast mcs mk2 p38 precipitated proinflammatory prompted raw respective stability tis11 translation tristetraprolin ttp unexpectedly
Tagcloud (Difference) ?		arginine bcl3 casp10 dap1 derepression epigenetic epigenetically governs hdac1 hodgkin hoxa5 hrk indirectly lymphoma master methyltransferase offer p52 polycomb prc2 prmt5 rb1 reactivation repression repressor retinoblastoma tp53k372 trigger turn	accomplished bmmc bmmcs brf1 connected cytokine deficient dependence dispensable exerted influencing initially lps lysates mast mcs mk2 p38 precipitated proinflammatory prompted raw respective stability tis11 translation tristetraprolin ttp unexpectedly
Tagcloud (Intersection) ?