RARRES3 and TGM1

Number of citations of the paper that reports this interaction (PMID 15846304)
13

Data Source:
HPRD (in vitro)

		RARRES3	TGM1
Gene Name		retinoic acid receptor responder (tazarotene induced) 3	transglutaminase 1
Image
Gene Ontology Annotations	Cellular Component	Integral Component Of Membrane	Cornified Envelope Cell-cell Adherens Junction Intrinsic Component Of Membrane Extracellular Vesicular Exosome
	Molecular Function	Phospholipase A2 Activity Protein Binding	Protein-glutamine Gamma-glutamyltransferase Activity Protein Binding Metal Ion Binding
	Biological Process	Phospholipid Metabolic Process Negative Regulation Of Cell Proliferation Lipid Catabolic Process	Cellular Protein Modification Process Organ Morphogenesis Peptide Cross-linking Keratinocyte Differentiation Keratinization Cell Envelope Organization
Pathways
Drugs
Diseases
GWAS
Protein-Protein Interactions		6 interactors: HRAS RNF135 SGTA TGM1 TRIM25 UBC	6 interactors: HSPB1 MDK RARRES3 SEMG1 SEMG2 SNCA
Entrez ID		5920	7051
HPRD ID		05479	01824
Ensembl ID		ENSG00000133321	ENSG00000092295
Uniprot IDs		Q9UL19	P22735
PDB IDs		2LKT	2XZZ
Enriched GO Terms of Interacting Partners?		Negative Regulation Of Type I Interferon Production Regulation Of Type I Interferon Production Negative Regulation Of Cytokine Production Innate Immune Response Immune Response Defense Response Positive Regulation Of Type I Interferon Production Regulation Of Cytokine Production Viral Process Protein Ubiquitination Protein Modification By Small Protein Conjugation Positive Regulation Of NF-kappaB Transcription Factor Activity Cell Envelope Organization Mitotic Cell Cycle Checkpoint Epidermal Growth Factor Receptor Signaling Pathway ERBB Signaling Pathway Fibroblast Growth Factor Receptor Signaling Pathway Positive Regulation Of Intracellular Signal Transduction Positive Regulation Of I-kappaB Kinase/NF-kappaB Signaling Immune System Process Regulation Of Immune Response Cellular Response To Fibroblast Growth Factor Stimulus Response To Fibroblast Growth Factor Positive Regulation Of Sequence-specific DNA Binding Transcription Factor Activity Neurotrophin TRK Receptor Signaling Pathway Positive Regulation Of MAP Kinase Activity Positive Regulation Of Rac Protein Signal Transduction Negative Regulation Of Mitotic Cell Cycle Neurotrophin Signaling Pathway Fc-epsilon Receptor Signaling Pathway MAPK Cascade Regulation Of I-kappaB Kinase/NF-kappaB Signaling Cell Cycle Checkpoint Positive Regulation Of MiRNA Metabolic Process Regulation Of Innate Immune Response Positive Regulation Of Ruffle Assembly Fc Receptor Signaling Pathway Activation Of Protein Kinase Activity Positive Regulation Of Protein Serine/threonine Kinase Activity Signal Transduction By Phosphorylation Regulation Of MAP Kinase Activity Positive Regulation Of Signal Transduction Regulation Of Sequence-specific DNA Binding Transcription Factor Activity Regulation Of MiRNA Metabolic Process Viral Protein Processing Regulation Of Immune System Process Apoptotic Signaling Pathway Positive Regulation Of Cytokine Production Immune Response-regulating Cell Surface Receptor Signaling Pathway Negative Regulation Of Rho GTPase Activity	Regulation Of Cellular Response To Oxidative Stress Negative Regulation Of Thrombin Receptor Signaling Pathway Negative Regulation Of Dopamine Uptake Involved In Synaptic Transmission Negative Regulation Of Norepinephrine Uptake Defecation Positive Regulation Of Hydrogen Peroxide Catabolic Process Positive Regulation Of Glutathione Peroxidase Activity Negative Regulation Of Mitochondrial Electron Transport, NADH To Ubiquinone Dopamine Uptake Involved In Synaptic Transmission Negative Regulation Of Serotonin Uptake Negative Regulation Of Dopamine Metabolic Process Negative Regulation Of Cellular Respiration Negative Regulation Of Neuron Apoptotic Process Regulation Of Behavior Negative Regulation Of Oxidative Phosphorylation Positive Regulation Of Endothelial Cell Chemotaxis By VEGF-activated Vascular Endothelial Growth Factor Receptor Signaling Pathway Negative Regulation Of Synaptic Transmission, Dopaminergic Negative Regulation Of Apoptotic Process Negative Regulation Of Programmed Cell Death Negative Regulation Of Neuron Death Positive Regulation Of Cell Migration By Vascular Endothelial Growth Factor Signaling Pathway Negative Regulation Of Cell Death Response To Iron(II) Ion Cellular Response To Copper Ion Regulation Of Neuron Apoptotic Process Regulation Of Synaptic Vesicle Recycling Positive Regulation Of Endothelial Cell Chemotaxis Regulation Of Neuron Death Regulation Of Dopamine Uptake Involved In Synaptic Transmission Regulation Of Oxidative Phosphorylation Positive Regulation Of Inositol Phosphate Biosynthetic Process Regulation Of Hydrogen Peroxide Metabolic Process Negative Regulation Of Protein Phosphorylation Dopamine Transport Regulation Of Glutamate Secretion Dopamine Biosynthetic Process Negative Regulation Of Monooxygenase Activity Neurotransmitter Uptake Regulation Of Cellular Respiration Microglial Cell Activation Extracellular Fibril Organization Negative Regulation Of Platelet-derived Growth Factor Receptor Signaling Pathway Synaptic Transmission, Dopaminergic Positive Regulation Of Tumor Necrosis Factor Biosynthetic Process Behavioral Response To Cocaine Short-term Memory Phospholipid Metabolic Process Regulation Of Neurotransmitter Uptake Negative Regulation Of Microtubule Polymerization Positive Regulation Of Neurotransmitter Secretion
Tagcloud ?		acyl acylation advance catenin cdd decision deregulation doi embryonic emerged fate indicates insight link lipoprotein mesenchymal modulates modulating november online pivotal publication serves tethers thioesterase transition tumorigenesis whereby wnt	accelerated b1 block blot cdk4 closely cycle cyclin cytometry displayed explore expressions g0 g1 g2 hacat immortalized immunocytochemistry inmmnohistochemistry interference interfering keratinocytes phases rnai silencing sirna transfecting transglutaminase western
Tagcloud (Difference) ?		acyl acylation advance catenin cdd decision deregulation doi embryonic emerged fate indicates insight link lipoprotein mesenchymal modulates modulating november online pivotal publication serves tethers thioesterase transition tumorigenesis whereby wnt	accelerated b1 block blot cdk4 closely cycle cyclin cytometry displayed explore expressions g0 g1 g2 hacat immortalized immunocytochemistry inmmnohistochemistry interference interfering keratinocytes phases rnai silencing sirna transfecting transglutaminase western
Tagcloud (Intersection) ?