TGM1

Gene Name		transglutaminase 1
Image
Gene Ontology Annotations	Cellular Component	Cornified Envelope Cell-cell Adherens Junction Intrinsic Component Of Membrane Extracellular Vesicular Exosome
	Molecular Function	Protein-glutamine Gamma-glutamyltransferase Activity Protein Binding Metal Ion Binding
	Biological Process	Cellular Protein Modification Process Organ Morphogenesis Peptide Cross-linking Keratinocyte Differentiation Keratinization Cell Envelope Organization
Pathways
Drugs
Diseases
GWAS
Protein-protein Interactions		6 interactors: HSPB1 MDK RARRES3 SEMG1 SEMG2 SNCA
Entrez ID		7051
HPRD ID		01824
Ensembl ID		ENSG00000092295
Uniprot IDs		P22735
PDB IDs		2XZZ
Enriched GO Terms of Interacting Partners?		Regulation Of Cellular Response To Oxidative Stress Negative Regulation Of Thrombin Receptor Signaling Pathway Negative Regulation Of Dopamine Uptake Involved In Synaptic Transmission Negative Regulation Of Norepinephrine Uptake Defecation Positive Regulation Of Hydrogen Peroxide Catabolic Process Positive Regulation Of Glutathione Peroxidase Activity Negative Regulation Of Mitochondrial Electron Transport, NADH To Ubiquinone Dopamine Uptake Involved In Synaptic Transmission Negative Regulation Of Serotonin Uptake Negative Regulation Of Dopamine Metabolic Process Negative Regulation Of Cellular Respiration Negative Regulation Of Neuron Apoptotic Process Regulation Of Behavior Negative Regulation Of Oxidative Phosphorylation Positive Regulation Of Endothelial Cell Chemotaxis By VEGF-activated Vascular Endothelial Growth Factor Receptor Signaling Pathway Negative Regulation Of Synaptic Transmission, Dopaminergic Negative Regulation Of Apoptotic Process Negative Regulation Of Programmed Cell Death Negative Regulation Of Neuron Death Positive Regulation Of Cell Migration By Vascular Endothelial Growth Factor Signaling Pathway Negative Regulation Of Cell Death Response To Iron(II) Ion Cellular Response To Copper Ion Regulation Of Neuron Apoptotic Process Regulation Of Synaptic Vesicle Recycling Positive Regulation Of Endothelial Cell Chemotaxis Regulation Of Neuron Death Regulation Of Dopamine Uptake Involved In Synaptic Transmission Regulation Of Oxidative Phosphorylation Positive Regulation Of Inositol Phosphate Biosynthetic Process Regulation Of Hydrogen Peroxide Metabolic Process Negative Regulation Of Protein Phosphorylation Dopamine Transport Regulation Of Glutamate Secretion Dopamine Biosynthetic Process Negative Regulation Of Monooxygenase Activity Neurotransmitter Uptake Regulation Of Cellular Respiration Microglial Cell Activation Extracellular Fibril Organization Negative Regulation Of Platelet-derived Growth Factor Receptor Signaling Pathway Synaptic Transmission, Dopaminergic Positive Regulation Of Tumor Necrosis Factor Biosynthetic Process Behavioral Response To Cocaine Short-term Memory Phospholipid Metabolic Process Regulation Of Neurotransmitter Uptake Negative Regulation Of Microtubule Polymerization Positive Regulation Of Neurotransmitter Secretion
Tagcloud ?		accelerated b1 block blot cdk4 closely cycle cyclin cytometry displayed explore expressions g0 g1 g2 hacat immortalized immunocytochemistry inmmnohistochemistry interference interfering keratinocytes phases rnai silencing sirna transfecting transglutaminase western