MAP3K11

Gene Name		mitogen-activated protein kinase kinase kinase 11
Image		No pdb structure
Gene Ontology Annotations	Cellular Component	Cytoplasm Centrosome Microtubule Membrane
	Molecular Function	Protein Kinase Activity Protein Serine/threonine Kinase Activity JUN Kinase Kinase Kinase Activity Protein Tyrosine Kinase Activity Protein Binding ATP Binding Mitogen-activated Protein Kinase Kinase Binding Mitogen-activated Protein Kinase Kinase Kinase Binding Identical Protein Binding Protein Homodimerization Activity Rac GTPase Binding
	Biological Process	Activation Of MAPK Activity Protein Phosphorylation Microtubule-based Process JNK Cascade Activation Of JNKK Activity Activation Of JUN Kinase Activity Cell Death Cell Proliferation Peptidyl-tyrosine Phosphorylation Positive Regulation Of JUN Kinase Activity Positive Regulation Of Neuron Apoptotic Process Positive Regulation Of JNK Cascade Protein Autophosphorylation
Pathways
Drugs
Diseases
GWAS
Protein-protein Interactions		27 interactors: AKT1 APP CDC42 CHUK CLEC4G COPS5 EPS8 IKBKB KIF17 KIF3A KIF3B KIFAP3 MAP2K4 MAP2K7 MAP3K12 MAP4K1 MAP4K2 MAPK8IP1 MAPK8IP2 MAPK8IP3 PIN1 RAC1 RHOG SH3RF1 STUB1 TRAF6 UBC
Entrez ID		4296
HPRD ID		02502
Ensembl ID		ENSG00000173327
Uniprot IDs		Q16584
PDB IDs
Enriched GO Terms of Interacting Partners?		Regulation Of JNK Cascade Regulation Of Stress-activated MAPK Cascade JNK Cascade Regulation Of MAPK Cascade Regulation Of Signal Transduction Stress-activated MAPK Cascade Stress-activated Protein Kinase Signaling Cascade Positive Regulation Of Transferase Activity Regulation Of Intracellular Signal Transduction Regulation Of Signaling Regulation Of Phosphorylation Response To Stress Regulation Of Phosphorus Metabolic Process Positive Regulation Of Signal Transduction Regulation Of Kinase Activity MAPK Cascade Regulation Of Protein Phosphorylation Positive Regulation Of Kinase Activity Positive Regulation Of Cellular Protein Metabolic Process Positive Regulation Of Protein Modification Process Positive Regulation Of Protein Phosphorylation Positive Regulation Of Cellular Metabolic Process Regulation Of Protein Kinase Activity Signal Transduction By Phosphorylation Positive Regulation Of Protein Metabolic Process Intracellular Signal Transduction Positive Regulation Of Catalytic Activity Positive Regulation Of Intracellular Signal Transduction Regulation Of Cellular Protein Metabolic Process Regulation Of Catalytic Activity Positive Regulation Of Phosphorylation Positive Regulation Of Stress-activated MAPK Cascade Positive Regulation Of Stress-activated Protein Kinase Signaling Cascade Regulation Of Protein Metabolic Process Regulation Of JUN Kinase Activity Fc Receptor Signaling Pathway Innate Immune Response Positive Regulation Of MAPK Cascade Signal Transduction Toll-like Receptor 5 Signaling Pathway Positive Regulation Of Metabolic Process Toll-like Receptor 10 Signaling Pathway Positive Regulation Of Protein Kinase Activity Toll-like Receptor TLR6:TLR2 Signaling Pathway Toll-like Receptor TLR1:TLR2 Signaling Pathway Immune System Process Toll-like Receptor 2 Signaling Pathway Positive Regulation Of JNK Cascade Toll-like Receptor 9 Signaling Pathway TRIF-dependent Toll-like Receptor Signaling Pathway
Tagcloud ?		acceleration activate agar besides carcinogenesis cdk2 colony crkl cycle cycling1 facilitate g1 htert mb mda methylate methyltransferase mynd oncogenes phenotypes pik3cb riz set smyd3 soft stat1 transduction transformed wnt10b