JPH3 and BGN

Number of citations of the paper that reports this interaction (PMID 11145944)
7

Data Source:
BioGRID (pull down)

		JPH3	BGN
Gene Name		junctophilin 3	biglycan
Image		No pdb structure	No pdb structure
Gene Ontology Annotations	Cellular Component	Plasma Membrane Junctional Sarcoplasmic Reticulum Membrane Integral Component Of Membrane Junctional Membrane Complex	Extracellular Region Proteinaceous Extracellular Matrix Golgi Lumen Cell Surface Transport Vesicle Extracellular Matrix Sarcolemma Lysosomal Lumen Extracellular Vesicular Exosome
	Molecular Function	Molecular_function Calcium-release Channel Activity	Extracellular Matrix Structural Constituent Glycosaminoglycan Binding Extracellular Matrix Binding
	Biological Process	Learning Memory Exploration Behavior Locomotion Regulation Of Neuronal Synaptic Plasticity Neuromuscular Process Controlling Balance Regulation Of Ryanodine-sensitive Calcium-release Channel Activity Calcium Ion Transport Into Cytosol Calcium Ion Transmembrane Transport	Blood Vessel Remodeling Carbohydrate Metabolic Process Biological_process Pathogenesis Peptide Cross-linking Via Chondroitin 4-sulfate Glycosaminoglycan Extracellular Matrix Organization Glycosaminoglycan Metabolic Process Chondroitin Sulfate Metabolic Process Chondroitin Sulfate Biosynthetic Process Chondroitin Sulfate Catabolic Process Dermatan Sulfate Biosynthetic Process Small Molecule Metabolic Process
Pathways			MPS IIIB - Sanfilippo syndrome B Diseases of glycosylation Heparan sulfate/heparin (HS-GAG) metabolism Defective B4GALT7 causes EDS, progeroid type MPS I - Hurler syndrome MPS IX - Natowicz syndrome Chondroitin sulfate/dermatan sulfate metabolism CS/DS degradation Defective SLC26A2 causes chondrodysplasias Glycosaminoglycan metabolism Defective B4GALT1 causes B4GALT1-CDG (CDG-2d) Defective CHST14 causes EDS, musculocontractural type Defective PAPSS2 causes SEMD-PA MPS IIIA - Sanfilippo syndrome A Myoclonic epilepsy of Lafora ECM proteoglycans Defective CHST6 causes MCDC1 Glycogen storage diseases MPS IIID - Sanfilippo syndrome D A tetrasaccharide linker sequence is required for GAG synthesis Chondroitin sulfate biosynthesis MPS IIIC - Sanfilippo syndrome C Diseases associated with glycosaminoglycan metabolism Mucopolysaccharidoses Defective EXT2 causes exostoses 2 MPS II - Hunter syndrome Defective B3GAT3 causes JDSSDHD Defective CHST3 causes SEDCJD Defective EXT1 causes exostoses 1, TRPS2 and CHDS MPS IV - Morquio syndrome A Dermatan sulfate biosynthesis Defective CHSY1 causes TPBS MPS IV - Morquio syndrome B MPS VII - Sly syndrome Metabolism of carbohydrates MPS VI - Maroteaux-Lamy syndrome
Drugs
Diseases
GWAS
Protein-Protein Interactions		3 interactors: BGN PPP1CA SMAD3	16 interactors: APOB APP BMP4 COL1A1 COL1A2 COL2A1 COL4A2 DAG1 ELN HDL3 JPH3 MFAP2 PLA2G1B TGFB1 TNF WISP1
Entrez ID		57338	633
HPRD ID		05589	02359
Ensembl ID		ENSG00000154118	ENSG00000182492
Uniprot IDs		B4DIC1 F8W9A3 Q8WXH2 Q96HD8	B4DNL4 P21810 Q8NAB7
PDB IDs
Enriched GO Terms of Interacting Partners?		Negative Regulation Of Transforming Growth Factor Beta Receptor Signaling Pathway Regulation Of Transforming Growth Factor Beta Receptor Signaling Pathway Negative Regulation Of Transmembrane Receptor Protein Serine/threonine Kinase Signaling Pathway Negative Regulation Of Cellular Response To Growth Factor Stimulus Transforming Growth Factor Beta Receptor Signaling Pathway Positive Regulation Of Transforming Growth Factor Beta3 Production Cellular Response To Transforming Growth Factor Beta Stimulus Regulation Of Cellular Response To Growth Factor Stimulus Response To Transforming Growth Factor Beta Positive Regulation Of Apoptotic Signaling Pathway Transmembrane Receptor Protein Serine/threonine Kinase Signaling Pathway Evasion Or Tolerance Of Host Defenses By Virus Activation Of Cysteine-type Endopeptidase Activity Involved In Apoptotic Signaling Pathway Positive Regulation Of Extracellular Matrix Assembly Regulation Of Extracellular Matrix Assembly Primary MiRNA Processing Epithelial Tube Morphogenesis Positive Regulation Of Cysteine-type Endopeptidase Activity Involved In Apoptotic Signaling Pathway SMAD Protein Complex Assembly Negative Regulation Of Osteoblast Proliferation Tube Morphogenesis Transdifferentiation Regulation Of Transforming Growth Factor Beta2 Production Regulation Of Glycogen Catabolic Process Positive Regulation Of Catenin Import Into Nucleus Dermatan Sulfate Biosynthetic Process Positive Regulation Of Alkaline Phosphatase Activity Morphogenesis Of An Epithelium Paraxial Mesoderm Morphogenesis Dermatan Sulfate Proteoglycan Biosynthetic Process Cellular Response To Growth Factor Stimulus Dermatan Sulfate Proteoglycan Metabolic Process Peptide Cross-linking Via Chondroitin 4-sulfate Glycosaminoglycan Chondroitin Sulfate Catabolic Process Positive Regulation Of Apoptotic Process Positive Regulation Of Programmed Cell Death Response To Growth Factor Nodal Signaling Pathway Positive Regulation Of Cell Death Positive Regulation Of Transforming Growth Factor Beta Production Tissue Morphogenesis Regulation Of Osteoblast Proliferation Embryonic Foregut Morphogenesis Positive Regulation Of Focal Adhesion Assembly Triglyceride Catabolic Process Tube Development Positive Regulation Of Adherens Junction Organization Production Of MiRNAs Involved In Gene Silencing By MiRNA Foregut Morphogenesis Chondroitin Sulfate Biosynthetic Process	Extracellular Matrix Organization Extracellular Structure Organization Locomotion Anatomical Structure Morphogenesis Multicellular Organismal Metabolic Process Movement Of Cell Or Subcellular Component Extracellular Matrix Disassembly Response To External Stimulus Organ Morphogenesis Protein Localization To Nucleus Collagen Catabolic Process Cell Morphogenesis Involved In Differentiation Collagen Metabolic Process Multicellular Organismal Macromolecule Metabolic Process Leukocyte Migration System Development Response To Organic Substance Cellular Response To Organic Substance Negative Regulation Of Myoblast Differentiation Response To Hormone Cellular Response To Growth Factor Stimulus Bone Morphogenesis Chemotaxis Multicellular Organismal Development Response To Growth Factor Immune System Process Anatomical Structure Development Cell Morphogenesis Organ Development Salivary Gland Morphogenesis Endochondral Ossification Gland Morphogenesis Regulation Of Myoblast Differentiation Salivary Gland Development Negative Regulation Of Muscle Cell Differentiation Cellular Response To Acid Chemical Cellular Response To Lipid Cellular Response To Transforming Growth Factor Beta Stimulus Blood Coagulation Hemostasis Developmental Process Exocrine System Development Response To Transforming Growth Factor Beta Platelet Activation Cartilage Development Common-partner SMAD Protein Phosphorylation Cell Migration Cellular Response To Amino Acid Stimulus Collagen Fibril Organization Cardiovascular System Development
Tagcloud ?		aldh1a1 asct beadchip carries cep192 cpeb1 detoxification dhrs7c dmrta1 fbn2 flj35282 grades gwas humanomni1 illumina interrupted linc00692 looked melphalan mucositis om predisposition quad sequelae snps tt2 tt3 tt4 v1	bambara bean beverage bgnm bgns boiled cow cowpea crop crops drought eaten fermented groundnut irritable legume legumes neglected nutritious probiotic probiotics relish roasted salted snack subterraenea traced verdc vigna
Tagcloud (Difference) ?		aldh1a1 asct beadchip carries cep192 cpeb1 detoxification dhrs7c dmrta1 fbn2 flj35282 grades gwas humanomni1 illumina interrupted linc00692 looked melphalan mucositis om predisposition quad sequelae snps tt2 tt3 tt4 v1	bambara bean beverage bgnm bgns boiled cow cowpea crop crops drought eaten fermented groundnut irritable legume legumes neglected nutritious probiotic probiotics relish roasted salted snack subterraenea traced verdc vigna
Tagcloud (Intersection) ?