BAAT and SLC7A11

Number of citations of the paper that reports this interaction (PMID 12763038)
3

Data Source:
HPRD (in vitro)

		BAAT	SLC7A11
Gene Name		bile acid CoA:amino acid N-acyltransferase	solute carrier family 7 (anionic amino acid transporter light chain, xc- system), member 11
Image		No pdb structure	No pdb structure
Gene Ontology Annotations	Cellular Component	Peroxisome Peroxisomal Matrix Cytosol	Rough Endoplasmic Reticulum Cytoskeleton Plasma Membrane Cell Surface Integral Component Of Membrane
	Molecular Function	Receptor Binding Palmitoyl-CoA Hydrolase Activity N-acyltransferase Activity Glycine N-choloyltransferase Activity Carboxylic Ester Hydrolase Activity Medium-chain Acyl-CoA Hydrolase Activity Long-chain Acyl-CoA Hydrolase Activity Very Long Chain Acyl-CoA Hydrolase Activity	Protein Binding Cystine:glutamate Antiporter Activity
	Biological Process	Liver Development Bile Acid Conjugation Glycine Metabolic Process Fatty Acid Metabolic Process Acyl-CoA Metabolic Process Bile Acid Biosynthetic Process Bile Acid Metabolic Process Bile Acid And Bile Salt Transport Taurine Metabolic Process Organ Regeneration Small Molecule Metabolic Process	Ion Transport Amino Acid Transport Response To Oxidative Stress Brain Development Blood Coagulation Response To Toxic Substance Response To Nicotine Leukocyte Migration Transmembrane Transport Lens Fiber Cell Differentiation Platelet Aggregation L-glutamate Transmembrane Transport
Pathways		Bile acid and bile salt metabolism Metabolism of lipids and lipoproteins Synthesis of bile acids and bile salts via 7alpha-hydroxycholesterol Recycling of bile acids and salts Synthesis of bile acids and bile salts	Transport of inorganic cations/anions and amino acids/oligopeptides Amino acid transport across the plasma membrane SLC-mediated transmembrane transport Basigin interactions Cell surface interactions at the vascular wall
Drugs			L-Cystine L-Glutamic Acid Riluzole Sulfasalazine
Diseases
GWAS
Protein-Protein Interactions		5 interactors: GOLGA8DP GOLGA8EP GOLGA8F PEX5 SLC7A11	3 interactors: BAAT SLC3A2 TERT
Entrez ID		570	23657
HPRD ID		08376	09720
Ensembl ID		ENSG00000136881	ENSG00000151012
Uniprot IDs		Q14032	Q9UPY5
PDB IDs
Enriched GO Terms of Interacting Partners?		Negative Regulation Of Protein Homotetramerization Protein Import Into Peroxisome Matrix, Translocation Protein Import Into Peroxisome Matrix, Docking Negative Regulation Of Protein Homooligomerization Protein Import Into Peroxisome Membrane Protein To Membrane Docking Peroxisomal Membrane Transport Negative Regulation Of Protein Oligomerization Brain Development Protein Import Into Peroxisome Matrix Head Development Cell Migration Cell Motility L-glutamate Transmembrane Transport Central Nervous System Development Establishment Of Protein Localization To Peroxisome Protein Targeting To Peroxisome Very Long-chain Fatty Acid Metabolic Process L-glutamate Transport Cerebral Cortex Neuron Differentiation Regulation Of Protein Oligomerization Locomotion Lens Fiber Cell Differentiation Platelet Aggregation Response To Nicotine Endoplasmic Reticulum Organization Fatty Acid Beta-oxidation Peroxisome Organization Positive Regulation Of Multicellular Organism Growth Movement Of Cell Or Subcellular Component Neutral Amino Acid Transport Intracellular Protein Transmembrane Transport Mitochondrial Membrane Organization Protein Transmembrane Transport Fatty Acid Oxidation Lipid Oxidation L-alpha-amino Acid Transmembrane Transport Fatty Acid Catabolic Process Transmembrane Transport Dicarboxylic Acid Transport Cerebral Cortex Cell Migration Membrane Docking Regulation Of Multicellular Organism Growth Telencephalon Cell Migration Lens Development In Camera-type Eye Forebrain Cell Migration Protein Tetramerization Nervous System Development Amino Acid Transmembrane Transport Neuromuscular Process	Response To DsRNA Leucine Import Bile Acid Conjugation Negative Regulation Of Production Of SiRNA Involved In RNA Interference Tryptophan Transport Negative Regulation Of RNA Interference Transcription, RNA-templated Telomere Formation Via Telomerase Age-dependent Telomere Shortening Aromatic Amino Acid Transport Telomere Maintenance Via Telomere Shortening Carboxylic Acid Transport Organic Acid Transport Leucine Transport Telomere Assembly Taurine Metabolic Process Organic Anion Transport Branched-chain Amino Acid Transport Replicative Cell Aging Telomere Maintenance Via Telomerase Production Of SiRNA Involved In RNA Interference Amino Acid Import RNA Interference Replicative Senescence Anion Transport RNA-dependent DNA Replication Bile Acid Biosynthetic Process Regulation Of Gene Silencing DNA Strand Elongation Telomere Maintenance Via Telomere Lengthening Bile Acid And Bile Salt Transport Response To Organic Cyclic Compound Glycine Metabolic Process Cellular Response To DsRNA Bile Acid Metabolic Process Posttranscriptional Gene Silencing Neutral Amino Acid Transport Response To Exogenous DsRNA Serine Family Amino Acid Metabolic Process Negative Regulation Of Extrinsic Apoptotic Signaling Pathway In Absence Of Ligand Gene Silencing By RNA Acyl-CoA Metabolic Process Cell Aging Organ Regeneration Telomere Maintenance Regulation Of Extrinsic Apoptotic Signaling Pathway In Absence Of Ligand Gene Silencing Amino Acid Transmembrane Transport DNA Biosynthetic Process Steroid Biosynthetic Process
Tagcloud ?			adapt anionic cannabidiol cannabinoid cbd combinatorial endowed gbm gsc gscs id1 mes modulators nfe2l2 pn proneural psychoactive redox regrowth renewal reprogramming resist ros solute sox2 taqman therapeutics xc xct
Tagcloud (Difference) ?			adapt anionic cannabidiol cannabinoid cbd combinatorial endowed gbm gsc gscs id1 mes modulators nfe2l2 pn proneural psychoactive redox regrowth renewal reprogramming resist ros solute sox2 taqman therapeutics xc xct
Tagcloud (Intersection) ?