SLC7A11

Gene Name		solute carrier family 7 (anionic amino acid transporter light chain, xc- system), member 11
Image		No pdb structure
Gene Ontology Annotations	Cellular Component	Rough Endoplasmic Reticulum Cytoskeleton Plasma Membrane Cell Surface Integral Component Of Membrane
	Molecular Function	Protein Binding Cystine:glutamate Antiporter Activity
	Biological Process	Ion Transport Amino Acid Transport Response To Oxidative Stress Brain Development Blood Coagulation Response To Toxic Substance Response To Nicotine Leukocyte Migration Transmembrane Transport Lens Fiber Cell Differentiation Platelet Aggregation L-glutamate Transmembrane Transport
Pathways		Transport of inorganic cations/anions and amino acids/oligopeptides Amino acid transport across the plasma membrane SLC-mediated transmembrane transport Basigin interactions Cell surface interactions at the vascular wall
Drugs		L-Cystine L-Glutamic Acid Riluzole Sulfasalazine
Diseases
GWAS
Protein-protein Interactions		3 interactors: BAAT SLC3A2 TERT
Entrez ID		23657
HPRD ID		09720
Ensembl ID		ENSG00000151012
Uniprot IDs		Q9UPY5
PDB IDs
Enriched GO Terms of Interacting Partners?		Response To DsRNA Leucine Import Bile Acid Conjugation Negative Regulation Of Production Of SiRNA Involved In RNA Interference Tryptophan Transport Negative Regulation Of RNA Interference Transcription, RNA-templated Telomere Formation Via Telomerase Age-dependent Telomere Shortening Aromatic Amino Acid Transport Telomere Maintenance Via Telomere Shortening Carboxylic Acid Transport Organic Acid Transport Leucine Transport Telomere Assembly Taurine Metabolic Process Organic Anion Transport Branched-chain Amino Acid Transport Replicative Cell Aging Telomere Maintenance Via Telomerase Production Of SiRNA Involved In RNA Interference Amino Acid Import RNA Interference Replicative Senescence Anion Transport RNA-dependent DNA Replication Bile Acid Biosynthetic Process Regulation Of Gene Silencing DNA Strand Elongation Telomere Maintenance Via Telomere Lengthening Bile Acid And Bile Salt Transport Response To Organic Cyclic Compound Glycine Metabolic Process Cellular Response To DsRNA Bile Acid Metabolic Process Posttranscriptional Gene Silencing Neutral Amino Acid Transport Response To Exogenous DsRNA Serine Family Amino Acid Metabolic Process Negative Regulation Of Extrinsic Apoptotic Signaling Pathway In Absence Of Ligand Gene Silencing By RNA Acyl-CoA Metabolic Process Cell Aging Organ Regeneration Telomere Maintenance Regulation Of Extrinsic Apoptotic Signaling Pathway In Absence Of Ligand Gene Silencing Amino Acid Transmembrane Transport DNA Biosynthetic Process Steroid Biosynthetic Process
Tagcloud ?		adapt anionic cannabidiol cannabinoid cbd combinatorial endowed gbm gsc gscs id1 mes modulators nfe2l2 pn proneural psychoactive redox regrowth renewal reprogramming resist ros solute sox2 taqman therapeutics xc xct