MRPS22 and SUMO4

Number of citations of the paper that reports this interaction (PMID 16236267)
15

Data Source:
HPRD (in vivo)

		MRPS22	SUMO4
Gene Name		mitochondrial ribosomal protein S22	small ubiquitin-like modifier 4
Image		No pdb structure	No pdb structure
Gene Ontology Annotations	Cellular Component	Mitochondrion Mitochondrial Inner Membrane Mitochondrial Ribosome Mitochondrial Small Ribosomal Subunit	Nucleus
	Molecular Function	Structural Constituent Of Ribosome
	Biological Process	Organelle Organization Biological_process Mitochondrial Translation Mitochondrial Translational Initiation Mitochondrial Translational Elongation Mitochondrial Translational Termination	Protein Sumoylation
Pathways		Mitochondrial translation Organelle biogenesis and maintenance Mitochondrial translation elongation Mitochondrial translation initiation Mitochondrial translation termination
Drugs
Diseases
GWAS		Obesity and blood pressure ( 22013104) Obesity-related traits ( 23251661)
Protein-Protein Interactions		2 interactors: BARD1 SUMO4	75 interactors: ACADM ACO2 ACTG1 ALDOA ARHGDIA ATP5B CALR CAT CCT2 CCT5 CCT6A CCT7 CLIC1 DNAJA1 DNAJB11 EIF3I ENO1 ENO2 FOS G6PD GAPDH GMPS GNB2L1 GSTP1 HNRNPD HNRNPF HNRNPH1 HNRNPL HSPA1B HSPA5 HSPA8 HSPA9 HSPD1 IDH1 IDH3A IMPDH2 JUN LDHB LMNA LMNB1 MRPS22 NFKBIA NR3C1 PA2G4 PAFAH1B3 PDIA3 PDIA6 PGK1 PHB PHGDH PITHD1 PPA1 PRDX2 PRDX3 PRDX4 PRDX6 PRPS1 PSMC2 RPSA SF3B4 SPINT2 STAT1 STAT3 STIP1 STOML2 STRAP TFAP2A TOP2A TPM3 TUBA1C TXNL1 UBE2V1 VCP VDAC1 ZPR1
Entrez ID		56945	387082
HPRD ID		10430	10584
Ensembl ID		ENSG00000175110	ENSG00000177688
Uniprot IDs		G5E9V5 P82650	Q6EEV6
PDB IDs
Enriched GO Terms of Interacting Partners?		Negative Regulation Of MRNA 3'-end Processing Negative Regulation Of Protein Export From Nucleus Protein K6-linked Ubiquitination Protein Modification By Small Protein Conjugation Regulation Of MRNA 3'-end Processing Protein Sumoylation Regulation Of Protein Export From Nucleus	Protein Folding Regulation Of Cell Death Regulation Of Apoptotic Process Cellular Metabolic Process Response To Unfolded Protein Response To Stress Negative Regulation Of Cell Death 'de Novo' Protein Folding Cellular Nitrogen Compound Metabolic Process Negative Regulation Of Apoptotic Process Negative Regulation Of Programmed Cell Death Toxin Transport Response To Organic Substance Nitrogen Compound Metabolic Process 'de Novo' Posttranslational Protein Folding Metabolic Process Cellular Response To Stress Heterocycle Metabolic Process Nucleobase-containing Compound Metabolic Process Response To Endoplasmic Reticulum Stress Generation Of Precursor Metabolites And Energy Regulation Of Cellular Protein Metabolic Process Response To Oxidative Stress Positive Regulation Of Cellular Metabolic Process Cellular Aromatic Compound Metabolic Process Cellular Process Response To Reactive Oxygen Species Small Molecule Metabolic Process Organic Acid Metabolic Process Hydrogen Peroxide Catabolic Process Regulation Of Protein Metabolic Process Carboxylic Acid Metabolic Process Protein Refolding Endoplasmic Reticulum Unfolded Protein Response Ribonucleoside Monophosphate Biosynthetic Process Carbohydrate Biosynthetic Process Cellular Response To Organic Substance MRNA Metabolic Process Cellular Response To Unfolded Protein Activation Of Signaling Protein Activity Involved In Unfolded Protein Response Positive Regulation Of Nuclease Activity Nucleoside Monophosphate Biosynthetic Process Gluconeogenesis Monocarboxylic Acid Metabolic Process ER-nucleus Signaling Pathway Catabolic Process Ribose Phosphate Biosynthetic Process Apoptotic Process Biosynthetic Process Cellular Response To Topologically Incorrect Protein
Tagcloud ?		ac acgh bmp7 cthrc1 discriminated distinctions driver drivers entities genomics grem1 helped hsa integrated lcc mirna mismatch ndrg1 pdgfb pik3ca recurrently rnf7 scc sox2 spink1 spp1 thpo tp63 utilize	accumulating behcet ccr1 ccr3 ccr6 cd40 ctla4 elucidating fcrl3 han helpful hopefully il17 il23r immunoregulatory irf5 l2 mcp multisystemic mystery opn predisposition profound ptpn22 regimes stat4 tgfbr3 tgrbr3 ubac2
Tagcloud (Difference) ?		ac acgh bmp7 cthrc1 discriminated distinctions driver drivers entities genomics grem1 helped hsa integrated lcc mirna mismatch ndrg1 pdgfb pik3ca recurrently rnf7 scc sox2 spink1 spp1 thpo tp63 utilize	accumulating behcet ccr1 ccr3 ccr6 cd40 ctla4 elucidating fcrl3 han helpful hopefully il17 il23r immunoregulatory irf5 l2 mcp multisystemic mystery opn predisposition profound ptpn22 regimes stat4 tgfbr3 tgrbr3 ubac2
Tagcloud (Intersection) ?