ARHGAP17 and FNBP1

Number of citations of the paper that reports this interaction (PMID 11431473)
23

Data Source:
HPRD (in vitro)

		ARHGAP17	FNBP1
Gene Name		Rho GTPase activating protein 17	formin binding protein 1
Image		No pdb structure
Gene Ontology Annotations	Cellular Component	Cytosol Plasma Membrane Tight Junction	Lysosome Cytoskeleton Plasma Membrane Coated Pit Cell Cortex Cytoplasmic Membrane-bounded Vesicle
	Molecular Function	GTPase Activator Activity Protein Binding SH3 Domain Binding	Protein Binding Lipid Binding Identical Protein Binding
	Biological Process	Small GTPase Mediated Signal Transduction Positive Regulation Of GTPase Activity Regulation Of Small GTPase Mediated Signal Transduction	Endocytosis
Pathways		Rho GTPase cycle Signaling by Rho GTPases
Drugs
Diseases
GWAS
Protein-Protein Interactions		16 interactors: ABL1 APP BTK CDC42 CRK CTTN DNMBP FNBP1 GRB2 LCK PACSIN1 PIK3R1 RAC1 SH3GLB1 SRC TRIP10	13 interactors: AKAP9 ARHGAP17 CBL CDC42 DNM1 DNM2 FASLG ITSN1 PDE6G RND2 SNX2 TNKS WASL
Entrez ID		55114	23048
HPRD ID		12207	10446
Ensembl ID		ENSG00000140750	ENSG00000187239
Uniprot IDs		Q68EM7	B7ZL12 B7ZL13 B7ZL14 Q96RU3
PDB IDs			2EFL
Enriched GO Terms of Interacting Partners?		Endocytosis Fc Receptor Signaling Pathway Immune Response-activating Cell Surface Receptor Signaling Pathway Vesicle-mediated Transport Immune Response-regulating Cell Surface Receptor Signaling Pathway Blood Coagulation Hemostasis Immune Response-regulating Signaling Pathway Fc-gamma Receptor Signaling Pathway Involved In Phagocytosis Fc-gamma Receptor Signaling Pathway Fc Receptor Mediated Stimulatory Signaling Pathway T Cell Costimulation Innate Immune Response Platelet Activation Regulation Of Body Fluid Levels Wound Healing Positive Regulation Of Immune Response Transmembrane Receptor Protein Tyrosine Kinase Signaling Pathway Cell Activation Response To Wounding Phagocytosis Positive Regulation Of Cell Activation Epidermal Growth Factor Receptor Signaling Pathway ERBB Signaling Pathway Regulation Of Immune Response Immune Response Enzyme Linked Receptor Protein Signaling Pathway Positive Regulation Of Immune System Process Defense Response Regulation Of Cell-cell Adhesion Neuron Projection Morphogenesis Regulation Of Lymphocyte Activation Positive Regulation Of T Cell Activation Neurotrophin TRK Receptor Signaling Pathway Positive Regulation Of Homotypic Cell-cell Adhesion Neurotrophin Signaling Pathway Leukocyte Migration Vascular Endothelial Growth Factor Receptor Signaling Pathway Regulation Of Signal Transduction Positive Regulation Of Cell-cell Adhesion Peptidyl-tyrosine Autophosphorylation Regulation Of Cell Activation Neuron Projection Development Cell Migration Regulation Of Phosphatidylinositol 3-kinase Activity Regulation Of T Cell Activation Cell Projection Morphogenesis Locomotion Transport Regulation Of Signaling	Regulation Of Epidermal Growth Factor Receptor Signaling Pathway Regulation Of ERBB Signaling Pathway Signal Transduction Ephrin Receptor Signaling Pathway Negative Regulation Of Membrane Tubulation Signaling Cell Communication Endocytosis Cellular Response To Stimulus Cell Projection Morphogenesis Cell Part Morphogenesis Cell Morphogenesis Neuron Projection Morphogenesis Cell Projection Organization Cell Development Transmembrane Receptor Protein Tyrosine Kinase Signaling Pathway Establishment Of Organelle Localization Response To Stimulus Positive Regulation Of Signal Transduction Axon Guidance Positive Regulation Of Intracellular Signal Transduction Neuron Projection Development Positive Regulation Of Epidermal Growth Factor Receptor Signaling Pathway Vesicle-mediated Transport Organelle Localization Cell Surface Receptor Signaling Pathway Enzyme Linked Receptor Protein Signaling Pathway Positive Regulation Of ERBB Signaling Pathway Cell-cell Signaling Generation Of Neurons Regulation Of Catalytic Activity Neuron Development Regulation Of Cell Projection Organization Nitric Oxide Metabolic Process Anatomical Structure Morphogenesis Cell Differentiation Positive Regulation Of Metabolic Process Neurogenesis Reactive Nitrogen Species Metabolic Process Endosome Organization Axonogenesis Positive Regulation Of Cellular Metabolic Process Establishment Of Vesicle Localization Regulation Of Intracellular Signal Transduction Vesicle Localization Positive Regulation Of Receptor-mediated Endocytosis Axon Development Regulation Of Nitric-oxide Synthase Activity Anatomical Structure Development Response To External Stimulus
Tagcloud ?			11p 12p 17q11 6q16 9p21 9q34 af10 c9orf78 calm concurring cryptic del grik2 hoxa imbalances immunophenotyping interphase inup214 leukemias lymphoblastic nup214 q11 q12 q34 q35 taf tcrb tlx3 usp20
Tagcloud (Difference) ?			11p 12p 17q11 6q16 9p21 9q34 af10 c9orf78 calm concurring cryptic del grik2 hoxa imbalances immunophenotyping interphase inup214 leukemias lymphoblastic nup214 q11 q12 q34 q35 taf tcrb tlx3 usp20
Tagcloud (Intersection) ?