ATP6V0A1 and CLIC1

Number of citations of the paper that reports this interaction (PMID 21988832)
14

Data Source:
BioGRID (two hybrid)

		ATP6V0A1	CLIC1
Gene Name		ATPase, H+ transporting, lysosomal V0 subunit a1	chloride intracellular channel 1
Image		No pdb structure
Gene Ontology Annotations	Cellular Component	Vacuolar Proton-transporting V-type ATPase, V0 Domain Nucleoplasm Cytoplasm Golgi Apparatus Plasma Membrane Endosome Membrane Integral Component Of Membrane Vacuolar Proton-transporting V-type ATPase Complex Phagocytic Vesicle Membrane Melanosome Intracellular Membrane-bounded Organelle Extracellular Vesicular Exosome	Extracellular Space Nucleus Nuclear Envelope Cytoplasm Mitochondrion Plasma Membrane Brush Border Membrane Nuclear Membrane Vesicle Chloride Channel Complex Perinuclear Region Of Cytoplasm Extracellular Vesicular Exosome Blood Microparticle
	Molecular Function	Protein Binding Proton-transporting ATPase Activity, Rotational Mechanism ATPase Binding	Voltage-gated Ion Channel Activity Chloride Channel Activity Protein Binding
	Biological Process	Cellular Iron Ion Homeostasis Vacuolar Acidification Insulin Receptor Signaling Pathway ATP Synthesis Coupled Proton Transport ATP Hydrolysis Coupled Proton Transport Transferrin Transport Interaction With Host Transmembrane Transport Vacuolar Proton-transporting V-type ATPase Complex Assembly Phagosome Maturation	Chloride Transport Signal Transduction Regulation Of Ion Transmembrane Transport Positive Regulation Of Osteoblast Differentiation Regulation Of Cell Cycle Regulation Of Mitochondrial Membrane Potential Platelet Aggregation Chloride Transmembrane Transport
Pathways		Phagosomal maturation (early endosomal stage) Iron uptake and transport Latent infection of Homo sapiens with Mycobacterium tuberculosis Transferrin endocytosis and recycling Insulin receptor recycling Signaling by Insulin receptor
Drugs
Diseases
GWAS
Protein-Protein Interactions		4 interactors: CLIC1 SEH1L SNX4 ZNF267	19 interactors: AKAP9 ALOX5AP ATP5F1 ATP6V0A1 ATP6V0C CPT1A IKBKG LSM1 MYOC NTF4 NUP62 PRDX4 PSMD10 RPLP1 SUMO4 THRA TRAPPC2 ZNF184 ZNF302
Entrez ID		535	1192
HPRD ID		01886	04188
Ensembl ID		ENSG00000033627	ENSG00000213719
Uniprot IDs		B7Z2A9 B7Z641 Q53ET5 Q53X12 Q5CZH6 Q93050	O00299 Q5SRT3
PDB IDs			1K0M 1K0N 1K0O 1RK4 3O3T 3P8W 3P90 3QR6 3SWL 3TGZ 3UVH 4IQA
Enriched GO Terms of Interacting Partners?		Positive Regulation Of Histamine Secretion By Mast Cell Regulation Of Histamine Secretion By Mast Cell Attachment Of Mitotic Spindle Microtubules To Kinetochore Cytokine Production Involved In Inflammatory Response Nuclear Pore Organization Attachment Of Spindle Microtubules To Kinetochore Positive Regulation Of Mast Cell Degranulation Positive Regulation Of Mast Cell Activation Positive Regulation Of Regulated Secretory Pathway Endocytic Recycling Regulation Of Ion Transport Regulation Of Mast Cell Degranulation Production Of Molecular Mediator Involved In Inflammatory Response Mitotic Metaphase Plate Congression Metaphase Plate Congression Regulation Of Mitochondrial Membrane Potential Mitotic Nuclear Envelope Disassembly Regulation Of Mast Cell Activation Platelet Aggregation Regulation Of Regulated Secretory Pathway Nuclear Envelope Disassembly Establishment Of Chromosome Localization	Nitrogen Compound Metabolic Process Viral Process Cellular Nitrogen Compound Metabolic Process Cytoplasmic Sequestering Of Transcription Factor Gene Expression Cytoplasmic Sequestering Of Protein Cellular Metabolic Process Negative Regulation Of Intracellular Signal Transduction Cellular Localization Heterocycle Metabolic Process Transferrin Transport ATP Synthesis Coupled Proton Transport Hydrogen Ion Transmembrane Transport ATP Biosynthetic Process Phagosome Maturation Proton Transport Negative Regulation Of Transcription Factor Import Into Nucleus Regulation Of I-kappaB Kinase/NF-kappaB Signaling Regulation Of Lipid Catabolic Process Negative Regulation Of Ras Protein Signal Transduction Negative Regulation Of Male Germ Cell Proliferation Skeletal Muscle Hypertrophy ERBB2-ERBB3 Signaling Pathway Sensory Organ Boundary Specification Negative Regulation Of Small GTPase Mediated Signal Transduction I-kappaB Kinase/NF-kappaB Signaling Cellular Response To Hormone Stimulus Nucleobase-containing Compound Metabolic Process ATP Hydrolysis Coupled Proton Transport Regulation Of MAPK Cascade Cellular Response To Stimulus Negative Regulation Of Protein Import Into Nucleus Small Molecule Metabolic Process Cellular Aromatic Compound Metabolic Process Monovalent Inorganic Cation Transport Purine Ribonucleoside Monophosphate Biosynthetic Process Biosynthetic Process RNA Biosynthetic Process Taste Bud Development ERBB2 Signaling Pathway Ganglion Mother Cell Fate Determination Negative Regulation Of RNA Polymerase II Transcriptional Preinitiation Complex Assembly Transmembrane Receptor Protein Tyrosine Kinase Signaling Pathway Negative Regulation Of Protein Localization To Nucleus RNA Metabolic Process Iron Ion Transport Cellular Iron Ion Homeostasis Nucleoside Triphosphate Biosynthetic Process Negative Regulation Of Intracellular Protein Transport Regulation Of Transcription Factor Import Into Nucleus
Tagcloud ?		acidification atpase autophagosomes betaa1 betaa3 cko coimmunoprecipitates cryba1 crystallin ctsd droplets electroretinography endolysosomal fundus helping knocked phagocytic phagocytosis photographs photoreceptor pigment pmtor raptor rpe rptor scattered undigested vacuole	aava accelerates atpase consolidating deregulated eevd endogenously enough gankyrin hek hot hub integrating interfaces mb mda migratory mutagenesis networks oncogenic oncoprotein pdb polypharmacological proteasome reflecting rescue searching silenced spot
Tagcloud (Difference) ?		acidification autophagosomes betaa1 betaa3 cko coimmunoprecipitates cryba1 crystallin ctsd droplets electroretinography endolysosomal fundus helping knocked phagocytic phagocytosis photographs photoreceptor pigment pmtor raptor rpe rptor scattered undigested vacuole	aava accelerates consolidating deregulated eevd endogenously enough gankyrin hek hot hub integrating interfaces mb mda migratory mutagenesis networks oncogenic oncoprotein pdb polypharmacological proteasome reflecting rescue searching silenced spot
Tagcloud (Intersection) ?		atpase