LUC7L2 and KLHL20

Number of citations of the paper that reports this interaction (PMID 16169070)
531

Data Source:
BioGRID (two hybrid)
HPRD (two hybrid)

		LUC7L2	KLHL20
Gene Name		LUC7-like 2 (S. cerevisiae)	kelch-like family member 20
Image		No pdb structure	No pdb structure
Gene Ontology Annotations	Cellular Component	U1 SnRNP Nuclear Speck	Cytoplasm Golgi Apparatus Trans-Golgi Network Actin Cytoskeleton PML Body Axon Dendrite Cul3-RING Ubiquitin Ligase Complex Perinuclear Region Of Cytoplasm
	Molecular Function	MRNA Binding Protein Binding Enzyme Binding Poly(A) RNA Binding	Actin Binding Ubiquitin-protein Transferase Activity Protein Binding Interferon-gamma Binding
	Biological Process	MRNA Splice Site Selection	Golgi To Endosome Transport Cytoskeleton Organization Protein Transport Protein Ubiquitination Response To Interferon-alpha Negative Regulation Of Apoptotic Process Proteasome-mediated Ubiquitin-dependent Protein Catabolic Process Protein K33-linked Ubiquitination
Pathways			Antigen processing: Ubiquitination & Proteasome degradation Class I MHC mediated antigen processing & presentation Adaptive Immune System
Drugs
Diseases
GWAS
Protein-Protein Interactions		54 interactors: AIMP2 ALB APP APPBP2 ATF7IP ATRX CADPS CCDC53 CDC37 CDK4 CDK5RAP2 CHD3 EXOC1 FAM173A FXR1 GADD45G GSK3B HAP1 HDHD2 IKBKG KIAA1377 KLHL20 LINC00341 LPL MAN2A2 MAP1LC3B NAP1L5 NASP NAT9 NDEL1 NDUFA4L2 NEDD4 NFYA NKAP NSF NUTF2 OFD1 PDPK1 PEA15 PIK3R3 PTCD3 PTN SAT1 SETDB1 SRPK1 SRPK2 SRSF6 SRSF7 SSFA2 SVIL ULK2 UNC119 YWHAG ZCCHC10	15 interactors: ACTA1 ARHGEF12 C14orf1 CORO7 CRMP1 CUL3 ECT2 EPAS1 GBP2 KIAA1377 LRIF1 LUC7L2 PIN1 PRMT6 SUV39H1
Entrez ID		51631	27252
HPRD ID		17456	13918
Ensembl ID		ENSG00000146963	ENSG00000076321
Uniprot IDs		Q9Y383	Q9Y2M5
PDB IDs
Enriched GO Terms of Interacting Partners?		Organelle Organization Establishment Of Localization In Cell Cellular Localization Protein Transport Regulation Of Kinase Activity Establishment Of Protein Localization Cell Cycle Process Anatomical Structure Development Intracellular Transport Cell Cycle Regulation Of MRNA Splicing, Via Spliceosome Regulation Of Metabolic Process Developmental Process Regulation Of Protein Kinase Activity Cellular Component Assembly Positive Regulation Of Cell Cycle Regulation Of MRNA Processing Negative Regulation Of Cellular Metabolic Process Regulation Of Cell Development Regulation Of Cell Differentiation Multicellular Organismal Development Regulation Of RNA Splicing Exocytosis Regulation Of Protein Metabolic Process Regulation Of Neurogenesis Establishment Of Cell Polarity Protein Localization Chromatin Organization Retrograde Axon Cargo Transport Regulation Of Cell Cycle Positive Regulation Of Cell Cycle Process Regulation Of Neuron Differentiation Nuclear Export Mitotic Cell Cycle Regulation Of Cell Size Apoptotic Process Axon Cargo Transport Programmed Cell Death Chromosome Organization Organelle Localization Regulation Of Cellular Process Regulation Of Cell Death Positive Regulation Of Mitotic Cell Cycle Phase Transition Cell Death Positive Regulation Of Metabolic Process Death Regulation Of Phosphorylation Positive Regulation Of Cell Cycle Phase Transition Regulation Of Protein Phosphorylation Regulation Of Gene Expression	Regulation Of Cytokinesis Regulation Of Rho Protein Signal Transduction Positive Regulation Of Cytokinesis Anatomical Structure Morphogenesis Cell Morphogenesis Positive Regulation Of Rho GTPase Activity Regulation Of Cell Division Regulation Of Ras Protein Signal Transduction Regulation Of Rho GTPase Activity Cellular Component Assembly Actin Filament Organization Regulation Of Small GTPase Mediated Signal Transduction Cell Cycle Apoptotic Signaling Pathway Regulation Of Chromosome Segregation Histone H3-R2 Methylation Skeletal Muscle Fiber Adaptation Organelle Organization Cellular Response To Hypoxia Cellular Response To Decreased Oxygen Levels Trophectodermal Cellular Morphogenesis Cellular Response To Oxygen Levels Positive Regulation Of Ras GTPase Activity Actomyosin Structure Organization Cell Differentiation Regulation Of Mitotic Nuclear Division Histone Methylation Positive Regulation Of Cell Division Negative Regulation Of Cyclin-dependent Protein Serine/threonine Kinase By Cyclin Degradation Regulation Of Cell Cycle Process Anatomical Structure Formation Involved In Morphogenesis Response To Abiotic Stimulus Cell Development Regulation Of Ras GTPase Activity Skeletal Muscle Thin Filament Assembly Histone H3-K9 Dimethylation Myoblast Fate Commitment Cytoskeleton Organization Positive Regulation Of Mitotic Metaphase/anaphase Transition Pyrimidine Nucleobase Catabolic Process Skeletal Myofibril Assembly Protein Methylation Actin Cytoskeleton Organization Skeletal Muscle Adaptation Adhesion Of Symbiont To Host
Tagcloud ?		add african alleles americans ankrd17 antihypertensive caucasian caucasians connections cox18 displaying diuretics elevations fto grin3a hctz heterozygotes hydrochlorothiazide hyperuricaemia padi4 pard3b pear pharmacogenomic replicated rs4784333 suggestive thiazide ua uric	angiopoietin bioinformatic blocking candidates canonical corneae corneal correlating correspondingly dystrophic dystrophy ect2 grew incomplete kelch kleip limbus lymphatics microarrays microrna mir neovascular neovascularization options pharmaceutical player proangiogenic vegf vision
Tagcloud (Difference) ?		add african alleles americans ankrd17 antihypertensive caucasian caucasians connections cox18 displaying diuretics elevations fto grin3a hctz heterozygotes hydrochlorothiazide hyperuricaemia padi4 pard3b pear pharmacogenomic replicated rs4784333 suggestive thiazide ua uric	angiopoietin bioinformatic blocking candidates canonical corneae corneal correlating correspondingly dystrophic dystrophy ect2 grew incomplete kelch kleip limbus lymphatics microarrays microrna mir neovascular neovascularization options pharmaceutical player proangiogenic vegf vision
Tagcloud (Intersection) ?