KLHL20

Gene Name		kelch-like family member 20
Image		No pdb structure
Gene Ontology Annotations	Cellular Component	Cytoplasm Golgi Apparatus Trans-Golgi Network Actin Cytoskeleton PML Body Axon Dendrite Cul3-RING Ubiquitin Ligase Complex Perinuclear Region Of Cytoplasm
	Molecular Function	Actin Binding Ubiquitin-protein Transferase Activity Protein Binding Interferon-gamma Binding
	Biological Process	Golgi To Endosome Transport Cytoskeleton Organization Protein Transport Protein Ubiquitination Response To Interferon-alpha Negative Regulation Of Apoptotic Process Proteasome-mediated Ubiquitin-dependent Protein Catabolic Process Protein K33-linked Ubiquitination
Pathways		Antigen processing: Ubiquitination & Proteasome degradation Class I MHC mediated antigen processing & presentation Adaptive Immune System
Drugs
Diseases
GWAS
Protein-protein Interactions		15 interactors: ACTA1 ARHGEF12 C14orf1 CORO7 CRMP1 CUL3 ECT2 EPAS1 GBP2 KIAA1377 LRIF1 LUC7L2 PIN1 PRMT6 SUV39H1
Entrez ID		27252
HPRD ID		13918
Ensembl ID		ENSG00000076321
Uniprot IDs		Q9Y2M5
PDB IDs
Enriched GO Terms of Interacting Partners?		Regulation Of Cytokinesis Regulation Of Rho Protein Signal Transduction Positive Regulation Of Cytokinesis Anatomical Structure Morphogenesis Cell Morphogenesis Positive Regulation Of Rho GTPase Activity Regulation Of Cell Division Regulation Of Ras Protein Signal Transduction Regulation Of Rho GTPase Activity Cellular Component Assembly Actin Filament Organization Regulation Of Small GTPase Mediated Signal Transduction Cell Cycle Apoptotic Signaling Pathway Regulation Of Chromosome Segregation Histone H3-R2 Methylation Skeletal Muscle Fiber Adaptation Organelle Organization Cellular Response To Hypoxia Cellular Response To Decreased Oxygen Levels Trophectodermal Cellular Morphogenesis Cellular Response To Oxygen Levels Positive Regulation Of Ras GTPase Activity Actomyosin Structure Organization Cell Differentiation Regulation Of Mitotic Nuclear Division Histone Methylation Positive Regulation Of Cell Division Negative Regulation Of Cyclin-dependent Protein Serine/threonine Kinase By Cyclin Degradation Regulation Of Cell Cycle Process Anatomical Structure Formation Involved In Morphogenesis Response To Abiotic Stimulus Cell Development Regulation Of Ras GTPase Activity Skeletal Muscle Thin Filament Assembly Histone H3-K9 Dimethylation Myoblast Fate Commitment Cytoskeleton Organization Positive Regulation Of Mitotic Metaphase/anaphase Transition Pyrimidine Nucleobase Catabolic Process Skeletal Myofibril Assembly Protein Methylation Actin Cytoskeleton Organization Skeletal Muscle Adaptation Adhesion Of Symbiont To Host
Tagcloud ?		angiopoietin bioinformatic blocking candidates canonical corneae corneal correlating correspondingly dystrophic dystrophy ect2 grew incomplete kelch kleip limbus lymphatics microarrays microrna mir neovascular neovascularization options pharmaceutical player proangiogenic vegf vision