SFMBT1 and PHC1

Number of citations of the paper that reports this interaction (PMID 16189514)
699

Data Source:
HPRD (two hybrid)

		SFMBT1	PHC1
Gene Name		Scm-like with four mbt domains 1	polyhomeotic homolog 1 (Drosophila)
Image		No pdb structure
Gene Ontology Annotations	Cellular Component	Nucleus Nucleoplasm	Sex Chromatin Nucleus Nucleoplasm Nuclear Body PcG Protein Complex PRC1 Complex
	Molecular Function	Transcription Corepressor Activity Protein Binding Histone Binding	DNA Binding Chromatin Binding Zinc Ion Binding
	Biological Process	Transcription, DNA-templated Spermatogenesis Chromatin Modification Cell Differentiation Negative Regulation Of Transcription, DNA-templated Negative Regulation Of Muscle Organ Development	Multicellular Organismal Development Histone Ubiquitination Cellular Response To Retinoic Acid
Pathways			Oxidative Stress Induced Senescence Cellular Senescence
Drugs
Diseases
GWAS		Bipolar disorder ( 21926972) Urate levels ( 23263486)
Protein-Protein Interactions		6 interactors: ACP1 PHC1 PHC2 PSMA1 SRPK1 ZCCHC10	18 interactors: BMI1 GMNN HSPA8 PCGF2 PHC2 PIAS2 PPP1CA PPP1CC RING1 RNF2 SCMH1 SFMBT1 SIAH1 SP100 SUMO1 SUMO1P1 UBE2I ZCCHC7
Entrez ID		51460	1911
HPRD ID		09539	16009
Ensembl ID		ENSG00000163935	ENSG00000111752
Uniprot IDs		Q9UHJ3	B4DF21 J3KQH6 P78364 Q6GMQ3 Q6N083
PDB IDs			2L8E
Enriched GO Terms of Interacting Partners?			Negative Regulation Of Transcription, DNA-templated Negative Regulation Of Nucleic Acid-templated Transcription Negative Regulation Of RNA Biosynthetic Process Negative Regulation Of Gene Expression Negative Regulation Of Biosynthetic Process Regulation Of Gene Expression Protein Modification By Small Protein Conjugation Negative Regulation Of Cellular Metabolic Process Chromatin Modification Chromatin Organization Regulation Of Metabolic Process Anterior/posterior Pattern Specification Peptidyl-lysine Modification Protein Sumoylation Regulation Of Transcription, DNA-templated Regulation Of Nucleic Acid-templated Transcription Regulation Of RNA Biosynthetic Process Protein Ubiquitination Histone Ubiquitination Regulation Of RNA Metabolic Process Chromosome Organization Transcription, DNA-templated Regulation Of Nitrogen Compound Metabolic Process RNA Biosynthetic Process Anatomical Structure Morphogenesis Cellular Protein Modification Process Pattern Specification Process Cellular Protein Metabolic Process Developmental Process Regulation Of Signal Transduction Histone H2A Monoubiquitination Histone H2A Ubiquitination Regulation Of Signaling Organelle Organization RNA Metabolic Process Histone Monoubiquitination Triglyceride Catabolic Process Entrainment Of Circadian Clock By Photoperiod Histone Modification Negative Regulation Of Transcription From RNA Polymerase II Promoter Gene Expression Protein Metabolic Process Photoperiodism Entrainment Of Circadian Clock Acylglycerol Catabolic Process Cell Division Cell Cycle Cellular Macromolecule Biosynthetic Process Nucleobase-containing Compound Metabolic Process Macromolecule Biosynthetic Process
Tagcloud ?		acquire carcinogenic catalyzing decipher demethylase demethylation dimethylated drivers emt ensuing h3k4me2 invasiveness kdm1a lsd1 lysines modifies nickel pollutant readers readouts recognizes recruiting represses reprogramming snai1 tgfbeta trimethyl unfavorable	bmi1a bmi1b cbx2 cbx4 cbx6a cbx6b cbx7a cbx7b cbx8a cbx8b combs enormous orthologs pcgf1 pcgf5a pcgf5b pcgf6 phc2a phc2b phc3 polyhomeotic prc1 psc ring1 rnf2 sce syntenies syntheses trimethylates
Tagcloud (Difference) ?		acquire carcinogenic catalyzing decipher demethylase demethylation dimethylated drivers emt ensuing h3k4me2 invasiveness kdm1a lsd1 lysines modifies nickel pollutant readers readouts recognizes recruiting represses reprogramming snai1 tgfbeta trimethyl unfavorable	bmi1a bmi1b cbx2 cbx4 cbx6a cbx6b cbx7a cbx7b cbx8a cbx8b combs enormous orthologs pcgf1 pcgf5a pcgf5b pcgf6 phc2a phc2b phc3 polyhomeotic prc1 psc ring1 rnf2 sce syntenies syntheses trimethylates
Tagcloud (Intersection) ?