AK3 and APPBP2

Number of citations of the paper that reports this interaction (PMID 25416956)
0

Data Source:
BioGRID (two hybrid)

		AK3	APPBP2
Gene Name		adenylate kinase 3	amyloid beta precursor protein (cytoplasmic tail) binding protein 2
Image			No pdb structure
Gene Ontology Annotations	Cellular Component	Mitochondrion Mitochondrial Matrix	Nucleus Cytoplasm Microtubule Microtubule Associated Complex Cytoplasmic Vesicle Membrane
	Molecular Function	Adenylate Kinase Activity ATP Binding GTP Binding Nucleoside Triphosphate Adenylate Kinase Activity	Microtubule Motor Activity Protein Binding
	Biological Process	ADP Biosynthetic Process Blood Coagulation Phosphorylation AMP Metabolic Process GTP Metabolic Process ITP Metabolic Process UTP Metabolic Process	Intracellular Protein Transport Metabolic Process Intracellular Transport
Pathways		Factors involved in megakaryocyte development and platelet production
Drugs
Diseases
GWAS		Crohn's disease ( 22412388) Hematological parameters ( 19820697) Platelet counts ( 22139419 20139978)
Protein-Protein Interactions		3 interactors: APPBP2 DAPK3 ZDHHC17	79 interactors: AHCY AIM2 AK3 ANKRD10 APP AR ARMCX5 C1orf50 C6orf226 CALM3 CCDC85C CCNL1 CDK16 CHMP5 CLCN1 CNTFR COL24A1 CORO2B CREB3 CSNK1G2 CTC1 DCD DHRS2 DPEP1 EID3 EPT1 ERO1L FAM19A4 FAM92A1 FSTL1 FXYD7 GALNT3 GCSAM GP9 GSTP1 HIPK4 HIST1H2AK HSPA4 KIF6 KLF11 KLHL35 LANCL2 LONRF3 LUC7L2 LUZP4 MFSD3 MGC34796 MLLT3 MUL1 NFYA NPRL3 PCSK5 PI4KAP2 PPP1R8 PRKAA2 PRKACB PYROXD2 RASSF5 RNF128 RNF34 RRS1 SELV SLC22A6 SLC25A23 SNX5 ST8SIA5 SYNRG SYT11 TAF11 TBL3 TCF25 UBE2R2 UGGT2 WAS WDR24 WNT5B ZC3H10 ZCCHC12 ZNF747
Entrez ID		50808	10513
HPRD ID		12439	05616
Ensembl ID			ENSG00000062725
Uniprot IDs		Q7Z4Y4 Q9UIJ7	Q92624
PDB IDs		1ZD8
Enriched GO Terms of Interacting Partners?			Regulation Of Defense Response To Virus By Host Response To Stress Nucleotide-binding Domain, Leucine Rich Repeat Containing Receptor Signaling Pathway Homocysteine Metabolic Process Cellular Response To Organic Substance
Tagcloud ?			10kb arhgap32 bcas3 breakpoints ccdc49 coamplification col14a1 coregulator ddx5 depdc6 deptor enpp2 hoxb9 lasp1 leukaemias nrip1 oprd1 painting pcgf2 phf20l1 plec1 skap1 taok1 tiam1 timm23 trps1 unamplified usp32 zmym4
Tagcloud (Difference) ?			10kb arhgap32 bcas3 breakpoints ccdc49 coamplification col14a1 coregulator ddx5 depdc6 deptor enpp2 hoxb9 lasp1 leukaemias nrip1 oprd1 painting pcgf2 phf20l1 plec1 skap1 taok1 tiam1 timm23 trps1 unamplified usp32 zmym4
Tagcloud (Intersection) ?