NFKBIE and KBTBD7

Number of citations of the paper that reports this interaction (PMID 21988832)
14

Data Source:
BioGRID (two hybrid)

		NFKBIE	KBTBD7
Gene Name		nuclear factor of kappa light polypeptide gene enhancer in B-cells inhibitor, epsilon	kelch repeat and BTB (POZ) domain containing 7
Image		No pdb structure	No pdb structure
Gene Ontology Annotations	Cellular Component	Cytoplasm Golgi Apparatus Cytosol Perinuclear Region Of Cytoplasm	Cellular_component
	Molecular Function	Protein Binding	Molecular_function Protein Binding
	Biological Process	D-serine Transport Cytoplasmic Sequestering Of Transcription Factor	Biological_process
Pathways		Signaling by the B Cell Receptor (BCR) Downstream signaling events of B Cell Receptor (BCR) Activation of NF-kappaB in B cells Adaptive Immune System
Drugs
Diseases
GWAS		Rheumatoid arthritis ( 22446963 23028356)
Protein-Protein Interactions		15 interactors: ANKHD1 C1QBP CUL1 HDAC4 HDAC5 IL1A JUP KBTBD7 NCOR2 NFKB1 NFKB2 PPP6C REL RELA SKP1	13 interactors: BARD1 BLMH C8orf33 CPT1A DUSP23 GABARAPL1 GABARAPL2 HAP1 LINC00341 LRIF1 MAP1LC3B NFKBIE PHC2
Entrez ID		4794	84078
HPRD ID		05181	13759
Ensembl ID		ENSG00000146232
Uniprot IDs		O00221 Q96F31	Q8WVZ9
PDB IDs
Enriched GO Terms of Interacting Partners?		Positive Regulation Of Sequence-specific DNA Binding Transcription Factor Activity Inflammatory Response Negative Regulation Of Transcription From RNA Polymerase II Promoter NIK/NF-kappaB Signaling Regulation Of Sequence-specific DNA Binding Transcription Factor Activity Regulation Of Interleukin-12 Biosynthetic Process Regulation Of Interleukin-12 Production Negative Regulation Of Transcription, DNA-templated Negative Regulation Of Nucleic Acid-templated Transcription Negative Regulation Of RNA Biosynthetic Process Regulation Of Transcription From RNA Polymerase II Promoter Positive Regulation Of Cellular Metabolic Process Negative Regulation Of Gene Expression Defense Response Negative Regulation Of Biosynthetic Process Regulation Of Cytokine Production Regulation Of Cytokine Biosynthetic Process Positive Regulation Of Macromolecule Biosynthetic Process Positive Regulation Of Gene Expression Positive Regulation Of Transcription From RNA Polymerase II Promoter Signal Transduction Positive Regulation Of Cellular Biosynthetic Process Notch Signaling Pathway Positive Regulation Of Cytokine Production Response To Cytokine Signaling Response To Organic Substance Positive Regulation Of Metabolic Process Cell Communication Positive Regulation Of Protein Metabolic Process Positive Regulation Of Transcription, DNA-templated Toll-like Receptor 5 Signaling Pathway Toll-like Receptor 10 Signaling Pathway Positive Regulation Of MiRNA Metabolic Process I-kappaB Kinase/NF-kappaB Signaling Toll-like Receptor TLR6:TLR2 Signaling Pathway Toll-like Receptor TLR1:TLR2 Signaling Pathway Toll-like Receptor 2 Signaling Pathway Toll-like Receptor 9 Signaling Pathway TRIF-dependent Toll-like Receptor Signaling Pathway Negative Regulation Of Cellular Metabolic Process Positive Regulation Of Cytokine Biosynthetic Process MyD88-independent Toll-like Receptor Signaling Pathway Toll-like Receptor 3 Signaling Pathway Immune System Process Regulation Of Protein Metabolic Process MyD88-dependent Toll-like Receptor Signaling Pathway Positive Regulation Of Interleukin-12 Biosynthetic Process Cellular Response To Nicotine Cellular Response To Stimulus	Nucleophagy Mitochondrion Degradation Autophagy Organelle Disassembly Autophagic Vacuole Assembly Macroautophagy Vacuole Organization Membrane Fusion Cellular Response To Nitrogen Starvation Cellular Response To Starvation Cellular Response To Nutrient Levels Response To Starvation Cellular Response To Extracellular Stimulus Cellular Response To Stress Positive Regulation Of Neurotrophin Production Positive Regulation Of Nonmotile Primary Cilium Assembly Mitochondrion Organization Catabolic Process Negative Regulation Of Intracellular Protein Transport Response To Nutrient Levels Regulation Of Cellular Localization Regulation Of Intracellular Transport D-serine Transport Negative Regulation Of MRNA 3'-end Processing Response To Extracellular Stimulus Organelle Assembly Negative Regulation Of Intracellular Transport Regulation Of Organelle Transport Along Microtubule Positive Regulation Of Inositol 1,4,5-trisphosphate-sensitive Calcium-release Channel Activity Positive Regulation Of Cilium Assembly Response To Drug Regulation Of Protein Transport Regulation Of Inositol 1,4,5-trisphosphate-sensitive Calcium-release Channel Activity Protein Polyubiquitination Negative Regulation Of Protein Export From Nucleus Regulation Of Establishment Of Protein Localization Negative Regulation Of Protein Transport Protein K6-linked Ubiquitination Positive Regulation Of Fatty Acid Beta-oxidation Carnitine Shuttle Regulation Of Nucleocytoplasmic Transport Hypothalamus Cell Differentiation Negative Regulation Of Beta-amyloid Formation Regulation Of Protein Localization Retrograde Axon Cargo Transport Carnitine Transmembrane Transport Carnitine Transport Membrane Organization Regulation Of Intracellular Protein Transport Negative Regulation Of Amyloid Precursor Protein Catabolic Process
Tagcloud ?		1980s a20 acquire bearing budding ccl17 ccl22 cd23 cd40 cd40l cd80 chemoattractant chronically costimulatory cytidine deaminase humoral hypergammaglobulinemia issued lymphotoxin map2k1 messengers nfkb1 productively tnip1 tonsillar traf1 virions
Tagcloud (Difference) ?		1980s a20 acquire bearing budding ccl17 ccl22 cd23 cd40 cd40l cd80 chemoattractant chronically costimulatory cytidine deaminase humoral hypergammaglobulinemia issued lymphotoxin map2k1 messengers nfkb1 productively tnip1 tonsillar traf1 virions
Tagcloud (Intersection) ?