NELL1 and ATN1

Number of citations of the paper that reports this interaction (PMID 16713569)
214

Data Source:
BioGRID (two hybrid)
HPRD (two hybrid)

		NELL1	ATN1
Gene Name		NEL-like 1 (chicken)	atrophin 1
Image		No pdb structure	No pdb structure
Gene Ontology Annotations	Cellular Component	Extracellular Region Nuclear Envelope Cytoplasm Perinuclear Region Of Cytoplasm	Nucleus Nucleoplasm Cytoplasm Nuclear Matrix Cell Junction Perinuclear Region Of Cytoplasm
	Molecular Function	Calcium Ion Binding Protein Binding	Transcription Corepressor Activity Protein Binding Protein Domain Specific Binding Toxin Receptor Binding
	Biological Process	Nervous System Development Regulation Of Gene Expression Cell Differentiation Positive Regulation Of Bone Mineralization Negative Regulation Of Osteoblast Proliferation Positive Regulation Of Osteoblast Differentiation Negative Regulation Of Cyclin Catabolic Process	Negative Regulation Of Transcription From RNA Polymerase II Promoter Transcription, DNA-templated Central Nervous System Development Toxin Metabolic Process Cell Migration Maintenance Of Cell Polarity Neuron Apoptotic Process
Pathways
Drugs
Diseases
GWAS		Adverse response to lamotrigine and phenytoin ( 22379998) Cannabis use (initiation) ( 22823124) Crohn's disease ( 17684544) Obesity-related traits ( 23251661) Response to amphetamines ( 22952603)
Protein-Protein Interactions		4 interactors: ATN1 ATXN7 CACNA1A GFI1B	93 interactors: AES AGRN ALG13 ARF3 ATRX BAG6 BAIAP2 CACNB1 CASP1 CASP3 CBFA2T2 CENPJ CHRD CRACR2A CRIP2 CTNND2 DMPK DVL1 DVL2 ECM1 EFEMP1 EFEMP2 EWSR1 FBLN1 FBLN2 FBLN5 GAPDH GCC1 GIGYF1 GRN HINFP HSPG2 ITCH JAG2 KAT6A KAT6B KAT7 KRT31 KRTAP4-12 LENG8 LRP2 LTBP1 LTBP4 LYST MAGI1 MAGI2 MAP7D1 MBP MDFI MEGF11 MEGF6 MEGF8 NCK2 NELL1 NELL2 NOC2L NR2E1 PCSK5 PDCD6IP PFKL PLSCR1 PRRC2A PRRC2B PSMA3 PSME3 RAD54L2 RBFOX1 RBFOX2 RBM10 RBPMS RCHY1 RERE RHOXF2 RNF115 RNF31 RUNX1T1 SIAH1 SIAH2 SLIT1 SPAG5 SSPO STXBP4 SYVN1 TEP1 TLE1 TRIP6 USP54 VIM WDR5 WWP1 WWP2 ZMYND8 ZSWIM8
Entrez ID		4745	1822
HPRD ID		09081	06311
Ensembl ID		ENSG00000165973	ENSG00000111676
Uniprot IDs		B3KXR2 F5H6I3 J3KNC5 Q92832	P54259 Q86V38
PDB IDs
Enriched GO Terms of Interacting Partners?		Negative Regulation Of Cellular Metabolic Process Cerebellar Molecular Layer Development Vestibular Nucleus Development Cerebellum Maturation Musculoskeletal Movement, Spinal Reflex Action Gamma-aminobutyric Acid Secretion Negative Regulation Of Biosynthetic Process Regulation Of Acetylcholine Secretion, Neurotransmission Rhythmic Synaptic Transmission Negative Regulation Of Insulin-like Growth Factor Receptor Signaling Pathway Calcium Ion-dependent Exocytosis Of Neurotransmitter Cellular Chloride Ion Homeostasis Gamma-aminobutyric Acid Transport Chloride Ion Homeostasis Regulation Of Transcription From RNA Polymerase II Promoter Negative Regulation Of Hormone Biosynthetic Process Pons Development Maintenance Of Cell Polarity Toxin Metabolic Process Cerebellar Purkinje Cell Differentiation Cerebellar Purkinje Cell Layer Morphogenesis Nitrogen Compound Metabolic Process Histone Deubiquitination Transcription, DNA-templated Reflex Regulation Of Insulin-like Growth Factor Receptor Signaling Pathway Chromatin Modification Behavioral Response To Pain RNA Biosynthetic Process Regulation Of Histone H3-K4 Methylation Neuromuscular Synaptic Transmission Regulation Of Hormone Biosynthetic Process Cerebellar Cortex Formation Neurotransmitter Metabolic Process Gamma-aminobutyric Acid Signaling Pathway Cell Differentiation In Hindbrain Chromatin Organization Calcium Ion Import Regulation Of Hormone Metabolic Process Cerebellar Purkinje Cell Layer Development Membrane Depolarization During Action Potential Negative Regulation Of Transcription From RNA Polymerase II Promoter Response To Pain Cerebellar Cortex Morphogenesis Synaptic Transmission, Glutamatergic Sulfur Amino Acid Metabolic Process Musculoskeletal Movement Calcium Ion-dependent Exocytosis Spinal Cord Motor Neuron Differentiation Anion Homeostasis	Regulation Of Cellular Process Regulation Of Metabolic Process Negative Regulation Of Cellular Metabolic Process Multicellular Organismal Development Regulation Of Nitrogen Compound Metabolic Process Developmental Process Regulation Of Gene Expression Signaling Regulation Of Signaling Signal Transduction Nervous System Development Anatomical Structure Development Cell Communication Negative Regulation Of Signaling Negative Regulation Of Signal Transduction Regulation Of RNA Metabolic Process Cellular Response To Stimulus Proteolysis Involved In Cellular Protein Catabolic Process Extracellular Matrix Organization Extracellular Structure Organization Cellular Protein Catabolic Process Regulation Of Nucleic Acid-templated Transcription Regulation Of Proteolysis Regulation Of RNA Biosynthetic Process System Development Response To Stimulus Cell Death Death Ubiquitin-dependent Protein Catabolic Process Anatomical Structure Morphogenesis Modification-dependent Protein Catabolic Process Protein Catabolic Process Apoptotic Process Negative Regulation Of Wnt Signaling Pathway Programmed Cell Death Regulation Of Transcription, DNA-templated Regulation Of Signal Transduction Negative Regulation Of Cellular Protein Metabolic Process Regulation Of Cellular Protein Metabolic Process Cellular Macromolecule Catabolic Process Regulation Of Protein Metabolic Process Negative Regulation Of Nucleic Acid-templated Transcription Negative Regulation Of RNA Biosynthetic Process Protein Ubiquitination Involved In Ubiquitin-dependent Protein Catabolic Process Negative Regulation Of Protein Metabolic Process Regulation Of Cellular Component Organization Enzyme Linked Receptor Protein Signaling Pathway Negative Regulation Of Biosynthetic Process Protein Ubiquitination Axon Development
Tagcloud ?		alleviate altering alternating american capillaries ccl2 closer coat concave convex dawley diepoxide endometrium eosin follicles ginseng glands hematoxylin ovarian pappa pla2g4a pof premature sprague stc2 uterine vcd vinylcyclohexene visible	atrophin1 atrophy chip cortical degenerative demethylase dentatorubral depletion h3k4 hint inducing knockout lbal lsd1 lysine maintenance methylation npc pallidoluysian phenocopied poorly precise premature progenitor repression rescued seq surprisingly tranylcypromine
Tagcloud (Difference) ?		alleviate altering alternating american capillaries ccl2 closer coat concave convex dawley diepoxide endometrium eosin follicles ginseng glands hematoxylin ovarian pappa pla2g4a pof sprague stc2 uterine vcd vinylcyclohexene visible	atrophin1 atrophy chip cortical degenerative demethylase dentatorubral depletion h3k4 hint inducing knockout lbal lsd1 lysine maintenance methylation npc pallidoluysian phenocopied poorly precise progenitor repression rescued seq surprisingly tranylcypromine
Tagcloud (Intersection) ?		premature