NAP1L4 and CSNK2A2

Number of citations of the paper that reports this interaction (PMID 10764593)
12

Data Source:
HPRD (in vitro)

		NAP1L4	CSNK2A2
Gene Name		nucleosome assembly protein 1-like 4	casein kinase 2, alpha prime polypeptide
Image		No pdb structure
Gene Ontology Annotations	Cellular Component	Nucleus Cytoplasm	Nucleus Cytosol PcG Protein Complex
	Molecular Function	Protein Binding Poly(A) RNA Binding Unfolded Protein Binding	Protein Serine/threonine Kinase Activity Protein Binding ATP Binding Protein N-terminus Binding
	Biological Process	Nucleosome Assembly	Mitotic Cell Cycle Transcription, DNA-templated Regulation Of Transcription, DNA-templated Protein Phosphorylation Apoptotic Process Axon Guidance Wnt Signaling Pathway Mitotic Spindle Checkpoint
Pathways			Mitotic Prometaphase Signal transduction by L1 Axon guidance misspliced LRP5 mutants have enhanced beta-catenin-dependent signaling L1CAM interactions Signaling by Wnt Cell Cycle, Mitotic M Phase WNT mediated activation of DVL TCF dependent signaling in response to WNT RNF mutants show enhanced WNT signaling and proliferation XAV939 inhibits tankyrase, stabilizing AXIN Signaling by WNT in cancer Condensation of Prometaphase Chromosomes
Drugs
Diseases
GWAS		Calcium levels ( 20705733)
Protein-Protein Interactions		10 interactors: CSNK2A1 CSNK2A2 EP300 HIST1H1A HIST1H2AE HIST2H2AC HIST2H2BE HIST2H3C HIST2H4A HIST3H3	92 interactors: ABCA1 ACACA ADH1A AQP4 ARR3 ARRB2 ASL ATF1 ATF2 BID CABP1 CALM1 CASQ2 CAV1 CDC37 CLTB CREBBP CREM CSN3 CSNK2B CTDP1 DCPS EEF1B2 EIF2B2 EIF2B5 EIF4EBP1 ERH FGF1 FGF2 FKBP3 FOS GTF2A1 GTF2A1L HDAC1 HDAC2 HDAC6 HIST1H1C HMGA1 HMGA2 HNRNPC HSP90AA1 HSP90B1 HSPH1 IL16 JUN KIF1C KLF1 LAMC3 LGALS3 MAF1 MAPK14 MGMT MS4A1 MYC MYCN MYF5 NAP1L4 NCL P4HB PAK1 PIN1 PIN4 PPP1R1B PPP1R2 PPP1R8 PRNP PTEN PTPN1 PTPRC RELA RGS19 SAT1 SLC18A2 SMURF1 SNCA SNX6 SPIB SPP1 STX1A TCF7L2 TCOF1 TGFBR1 TGM2 TOP1 TRIM41 TTLL12 UBE2R2 WAS XRCC1 ZNF219 ZNF670 ZNHIT3
Entrez ID		4676	1459
HPRD ID		11873	00279
Ensembl ID		ENSG00000205531	ENSG00000070770
Uniprot IDs		F5HFY4 Q99733	P19784
PDB IDs			3E3B 3OFM 3U87
Enriched GO Terms of Interacting Partners?		DNA Methylation On Cytosine Nucleosome Assembly Chromatin Silencing At RDNA Chromatin Assembly Nucleosome Organization Chromosome Organization Chromatin Assembly Or Disassembly Protein-DNA Complex Assembly DNA Packaging Chromatin Silencing Mitotic Spindle Checkpoint Negative Regulation Of Chromosome Segregation Chromatin Organization Mitotic Cell Cycle DNA Conformation Change Spindle Checkpoint Regulation Of Mitotic Sister Chromatid Separation Negative Regulation Of Mitotic Nuclear Division Regulation Of Mitotic Metaphase/anaphase Transition DNA Methylation Negative Regulation Of Proteasomal Ubiquitin-dependent Protein Catabolic Process Negative Regulation Of Proteasomal Protein Catabolic Process Negative Regulation Of Gene Expression, Epigenetic Histone H2B Acetylation Negative Regulation Of Cellular Protein Catabolic Process Telomere Maintenance Negative Regulation Of Cell Division Regulation Of Chromosome Segregation DNA Modification Negative Regulation Of Chromosome Organization Gene Silencing Negative Regulation Of Cellular Metabolic Process Negative Regulation Of Protein Catabolic Process Regulation Of Mitotic Nuclear Division N-terminal Peptidyl-lysine Acetylation Histone H4-K20 Demethylation Regulation Of Proteasomal Ubiquitin-dependent Protein Catabolic Process Cell Cycle Negative Regulation Of Mitotic Cell Cycle Phase Transition Positive Regulation Of Transcription From RNA Polymerase II Promoter Involved In Unfolded Protein Response Cellular Macromolecular Complex Assembly Negative Regulation Of Megakaryocyte Differentiation Regulation Of Tubulin Deacetylation Mitotic Cell Cycle Checkpoint Mitotic Cell Cycle Process Regulation Of Proteasomal Protein Catabolic Process Regulation Of Chromosome Organization Regulation Of Gene Expression, Epigenetic Regulation Of Mitotic Cell Cycle Phase Transition Negative Regulation Of Mitotic Cell Cycle	Response To Organic Substance Regulation Of Metabolic Process Positive Regulation Of Cellular Metabolic Process Response To Stress Response To Abiotic Stimulus Response To Organonitrogen Compound Positive Regulation Of Metabolic Process Cellular Metabolic Process Positive Regulation Of Cellular Biosynthetic Process Cellular Response To Stimulus Regulation Of Gene Expression Developmental Process Innate Immune Response Cellular Response To Organic Substance Positive Regulation Of Macromolecule Biosynthetic Process Regulation Of Protein Metabolic Process Regulation Of Immune System Process Response To Growth Factor Enzyme Linked Receptor Protein Signaling Pathway Tissue Development Regulation Of Signal Transduction Regulation Of Nitrogen Compound Metabolic Process Response To Stimulus Immune Response-regulating Signaling Pathway Cellular Response To Stress Regulation Of Protein Phosphorylation Regulation Of Catalytic Activity Regulation Of Cellular Protein Metabolic Process Cellular Response To Growth Factor Stimulus Regulation Of Immune Response Response To Organic Cyclic Compound Regulation Of Signaling Transcription, DNA-templated Regulation Of Phosphorus Metabolic Process Gene Expression Regulation Of Cell Death Negative Regulation Of Cellular Metabolic Process RNA Biosynthetic Process Immune Response Regulation Of Phosphorylation Cell Differentiation Negative Regulation Of Signal Transduction Anatomical Structure Development Nitrogen Compound Metabolic Process Multicellular Organismal Development Defense Response Macromolecule Biosynthetic Process Biosynthetic Process RNA Metabolic Process Positive Regulation Of Gene Expression
Tagcloud ?		11p15 approved cloning competition cooh deduced demonstrates etiology g401 hgmw histones intron linker mutagenesis mutational naked nh3 nucleosome onto packaging positional shuttle subcellular symbol templates wilms wt wts	bovine casein catalytic cattle chromosome chromosomes coast composed conserved defined east encoding fever genomes homology hybrid mapped panel parasitic polymerase rodent segment somatic subunit subunits synteny theileriosis
Tagcloud (Difference) ?		11p15 approved cloning competition cooh deduced demonstrates etiology g401 hgmw histones intron linker mutagenesis mutational naked nh3 nucleosome onto packaging positional shuttle subcellular symbol templates wilms wt wts	bovine casein catalytic cattle chromosome chromosomes coast composed conserved defined east encoding fever genomes homology hybrid mapped panel parasitic polymerase rodent segment somatic subunit subunits synteny theileriosis
Tagcloud (Intersection) ?