MYO9B and ARFGEF1

Number of citations of the paper that reports this interaction (PMID 15644318)
6

Data Source:
HPRD (in vitro, two hybrid)

		MYO9B	ARFGEF1
Gene Name		myosin IXB	ADP-ribosylation factor guanine nucleotide-exchange factor 1 (brefeldin A-inhibited)
Image		No pdb structure
Gene Ontology Annotations	Cellular Component	Ruffle Cytoplasm Cytosol Cell Cortex Actin Cytoskeleton Membrane Myosin Complex Lamellipodium Filamentous Actin Filopodium Tip Perinuclear Region Of Cytoplasm	Golgi Membrane Nucleoplasm Nucleolus Cytoplasm Golgi Apparatus Trans-Golgi Network Cytosol Nuclear Matrix Small Nuclear Ribonucleoprotein Complex Perinuclear Region Of Cytoplasm
	Molecular Function	Microfilament Motor Activity Actin Binding Rho GTPase Activator Activity Protein Binding Calmodulin Binding ATP Binding Zinc Ion Binding ATPase Activity Actin-dependent ATPase Activity Protein Homodimerization Activity ATP-dependent Protein Binding ADP Binding Actin Filament Binding	Guanyl-nucleotide Exchange Factor Activity ARF Guanyl-nucleotide Exchange Factor Activity Protein Binding ARF GTPase Activator Activity Myosin Binding Protein Kinase A Regulatory Subunit Binding
	Biological Process	Monocyte Chemotaxis Small GTPase Mediated Signal Transduction Rho Protein Signal Transduction Establishment Of Cell Polarity Actin Filament-based Movement ARF Protein Signal Transduction Positive Regulation Of Rho GTPase Activity Macrophage Chemotaxis Regulation Of Small GTPase Mediated Signal Transduction Lamellipodium Morphogenesis	Exocytosis Golgi Organization Endomembrane System Organization Protein Transport Vesicle-mediated Transport Negative Regulation Of Actin Filament Polymerization Regulation Of ARF Protein Signal Transduction Negative Regulation Of Rho GTPase Activity Positive Regulation Of GTPase Activity Positive Regulation Of Protein Glycosylation In Golgi Positive Regulation Of Wound Healing Regulation Of Establishment Of Cell Polarity
Pathways		Rho GTPase cycle Signaling by Rho GTPases Fcgamma receptor (FCGR) dependent phagocytosis Regulation of actin dynamics for phagocytic cup formation Innate Immune System
Drugs
Diseases
GWAS		Height ( 20881960)
Protein-Protein Interactions		6 interactors: ACTA1 ARFGEF1 CALM1 LRRC41 MOB4 PKN2	4 interactors: ARFGEF2 DPY30 FKBP2 MYO9B
Entrez ID		4650	10565
HPRD ID		03677	09163
Ensembl ID		ENSG00000099331	ENSG00000066777
Uniprot IDs		B0I1T6 Q13459 Q4LE74 Q8WVD2	Q9Y6D6
PDB IDs			3LTL
Enriched GO Terms of Interacting Partners?		Regulation Of Cytokinesis Positive Regulation Of Protein Glycosylation In Golgi Skeletal Muscle Fiber Adaptation Positive Regulation Of Cyclic-nucleotide Phosphodiesterase Activity Positive Regulation Of Protein Glycosylation Regulation Of High Voltage-gated Calcium Channel Activity Muscle Contraction Regulation Of Cell Communication By Electrical Coupling Involved In Cardiac Conduction Skeletal Muscle Thin Filament Assembly Regulation Of Cell Division Muscle System Process Positive Regulation Of Ryanodine-sensitive Calcium-release Channel Activity Skeletal Myofibril Assembly Skeletal Muscle Adaptation Negative Regulation Of Ryanodine-sensitive Calcium-release Channel Activity Regulation Of Protein Glycosylation Response To Metal Ion Exocytosis Detection Of Calcium Ion Regulation Of Cell Communication By Electrical Coupling Positive Regulation Of Phosphoprotein Phosphatase Activity Negative Regulation Of Rho GTPase Activity Positive Regulation Of Glycoprotein Biosynthetic Process Positive Regulation Of Peptidyl-threonine Phosphorylation Positive Regulation Of Glycoprotein Metabolic Process Positive Regulation Of Protein Autophosphorylation Positive Regulation Of Nitric-oxide Synthase Activity Regulation Of Cardiac Muscle Contraction By Regulation Of The Release Of Sequestered Calcium Ion Glycogen Catabolic Process Negative Regulation Of Calcium Ion Transmembrane Transporter Activity Negative Regulation Of Peptidyl-threonine Phosphorylation Regulation Of Voltage-gated Calcium Channel Activity Positive Regulation Of Protein Dephosphorylation Negative Regulation Of Ras GTPase Activity Negative Regulation Of Cation Channel Activity Polysaccharide Catabolic Process Positive Regulation Of Viral Genome Replication Response To Inorganic Substance Response To Steroid Hormone Positive Regulation Of Monooxygenase Activity Skeletal Muscle Fiber Development Regulation Of Cell Cycle Process Regulation Of Cardiac Muscle Contraction By Calcium Ion Signaling Positive Regulation Of Calcium Ion Transmembrane Transporter Activity Regulation Of Release Of Sequestered Calcium Ion Into Cytosol By Sarcoplasmic Reticulum Secretion By Cell Regulation Of Rhodopsin Mediated Signaling Pathway Regulation Of Ryanodine-sensitive Calcium-release Channel Activity Activation Of Adenylate Cyclase Activity Nitric Oxide Metabolic Process
Tagcloud ?		akap6 atf7 atxn1 bmpr2 categorize deltan eef1a1 grip2 gtf2f1 interactors jbd jbds jnk1alpha1 jnk3 jnk3alpha1 jnks kcne4 nnat pias1 ptgds ptpn2 rabgap1 rusc2 shank1 sumo1 sypl1 tkt topbp1 znf668
Tagcloud (Difference) ?		akap6 atf7 atxn1 bmpr2 categorize deltan eef1a1 grip2 gtf2f1 interactors jbd jbds jnk1alpha1 jnk3 jnk3alpha1 jnks kcne4 nnat pias1 ptgds ptpn2 rabgap1 rusc2 shank1 sumo1 sypl1 tkt topbp1 znf668
Tagcloud (Intersection) ?