MYO9B and LRRC41

Number of citations of the paper that reports this interaction (PMID 16169070)
531

Data Source:
BioGRID (two hybrid)
HPRD (two hybrid)

		MYO9B	LRRC41
Gene Name		myosin IXB	leucine rich repeat containing 41
Image		No pdb structure	No pdb structure
Gene Ontology Annotations	Cellular Component	Ruffle Cytoplasm Cytosol Cell Cortex Actin Cytoskeleton Membrane Myosin Complex Lamellipodium Filamentous Actin Filopodium Tip Perinuclear Region Of Cytoplasm	Nucleus Cytoplasm Membrane
	Molecular Function	Microfilament Motor Activity Actin Binding Rho GTPase Activator Activity Protein Binding Calmodulin Binding ATP Binding Zinc Ion Binding ATPase Activity Actin-dependent ATPase Activity Protein Homodimerization Activity ATP-dependent Protein Binding ADP Binding Actin Filament Binding	Protein Homodimerization Activity
	Biological Process	Monocyte Chemotaxis Small GTPase Mediated Signal Transduction Rho Protein Signal Transduction Establishment Of Cell Polarity Actin Filament-based Movement ARF Protein Signal Transduction Positive Regulation Of Rho GTPase Activity Macrophage Chemotaxis Regulation Of Small GTPase Mediated Signal Transduction Lamellipodium Morphogenesis	Protein Ubiquitination
Pathways		Rho GTPase cycle Signaling by Rho GTPases Fcgamma receptor (FCGR) dependent phagocytosis Regulation of actin dynamics for phagocytic cup formation Innate Immune System	Antigen processing: Ubiquitination & Proteasome degradation Class I MHC mediated antigen processing & presentation Adaptive Immune System
Drugs
Diseases
GWAS		Height ( 20881960)
Protein-Protein Interactions		6 interactors: ACTA1 ARFGEF1 CALM1 LRRC41 MOB4 PKN2	4 interactors: MYO9B RBPMS TCEB1 TCEB2
Entrez ID		4650	10489
HPRD ID		03677	10102
Ensembl ID		ENSG00000099331	ENSG00000132128
Uniprot IDs		B0I1T6 Q13459 Q4LE74 Q8WVD2	Q15345
PDB IDs
Enriched GO Terms of Interacting Partners?		Regulation Of Cytokinesis Positive Regulation Of Protein Glycosylation In Golgi Skeletal Muscle Fiber Adaptation Positive Regulation Of Cyclic-nucleotide Phosphodiesterase Activity Positive Regulation Of Protein Glycosylation Regulation Of High Voltage-gated Calcium Channel Activity Muscle Contraction Regulation Of Cell Communication By Electrical Coupling Involved In Cardiac Conduction Skeletal Muscle Thin Filament Assembly Regulation Of Cell Division Muscle System Process Positive Regulation Of Ryanodine-sensitive Calcium-release Channel Activity Skeletal Myofibril Assembly Skeletal Muscle Adaptation Negative Regulation Of Ryanodine-sensitive Calcium-release Channel Activity Regulation Of Protein Glycosylation Response To Metal Ion Exocytosis Detection Of Calcium Ion Regulation Of Cell Communication By Electrical Coupling Positive Regulation Of Phosphoprotein Phosphatase Activity Negative Regulation Of Rho GTPase Activity Positive Regulation Of Glycoprotein Biosynthetic Process Positive Regulation Of Peptidyl-threonine Phosphorylation Positive Regulation Of Glycoprotein Metabolic Process Positive Regulation Of Protein Autophosphorylation Positive Regulation Of Nitric-oxide Synthase Activity Regulation Of Cardiac Muscle Contraction By Regulation Of The Release Of Sequestered Calcium Ion Glycogen Catabolic Process Negative Regulation Of Calcium Ion Transmembrane Transporter Activity Negative Regulation Of Peptidyl-threonine Phosphorylation Regulation Of Voltage-gated Calcium Channel Activity Positive Regulation Of Protein Dephosphorylation Negative Regulation Of Ras GTPase Activity Negative Regulation Of Cation Channel Activity Polysaccharide Catabolic Process Positive Regulation Of Viral Genome Replication Response To Inorganic Substance Response To Steroid Hormone Positive Regulation Of Monooxygenase Activity Skeletal Muscle Fiber Development Regulation Of Cell Cycle Process Regulation Of Cardiac Muscle Contraction By Calcium Ion Signaling Positive Regulation Of Calcium Ion Transmembrane Transporter Activity Regulation Of Release Of Sequestered Calcium Ion Into Cytosol By Sarcoplasmic Reticulum Secretion By Cell Regulation Of Rhodopsin Mediated Signaling Pathway Regulation Of Ryanodine-sensitive Calcium-release Channel Activity Activation Of Adenylate Cyclase Activity Nitric Oxide Metabolic Process	Regulation Of Transcription From RNA Polymerase II Promoter In Response To Hypoxia Positive Regulation Of Viral Transcription Regulation Of Transcription From RNA Polymerase II Promoter In Response To Stress Regulation Of DNA-templated Transcription In Response To Stress Transcription Elongation From RNA Polymerase II Promoter Regulation Of Viral Transcription Positive Regulation Of Viral Process DNA-templated Transcription, Elongation Cellular Response To Hypoxia Cellular Response To Decreased Oxygen Levels Cellular Response To Oxygen Levels Regulation Of Viral Process Positive Regulation Of Metabolic Process Lamellipodium Morphogenesis Response To Hypoxia Positive Regulation Of SMAD Protein Import Into Nucleus Monocyte Chemotaxis Regulation Of SMAD Protein Import Into Nucleus Macrophage Chemotaxis Positive Regulation Of Transcription Elongation From RNA Polymerase II Promoter Viral Process Transcription, DNA-templated RNA Biosynthetic Process Positive Regulation Of DNA-templated Transcription, Elongation Positive Regulation Of Cellular Metabolic Process Regulation Of Transcription Elongation From RNA Polymerase II Promoter Positive Regulation Of Pathway-restricted SMAD Protein Phosphorylation Transcription From RNA Polymerase II Promoter Lamellipodium Organization Regulation Of DNA-templated Transcription, Elongation RNA Metabolic Process Regulation Of Pathway-restricted SMAD Protein Phosphorylation Rho Protein Signal Transduction Regulation Of Metabolic Process Actin Filament-based Movement Gene Expression Response To Abiotic Stimulus Cellular Macromolecule Biosynthetic Process Macromolecule Biosynthetic Process
Tagcloud ?		akap6 atf7 atxn1 bmpr2 categorize deltan eef1a1 grip2 gtf2f1 interactors jbd jbds jnk1alpha1 jnk3 jnk3alpha1 jnks kcne4 nnat pias1 ptgds ptpn2 rabgap1 rusc2 shank1 sumo1 sypl1 tkt topbp1 znf668
Tagcloud (Difference) ?		akap6 atf7 atxn1 bmpr2 categorize deltan eef1a1 grip2 gtf2f1 interactors jbd jbds jnk1alpha1 jnk3 jnk3alpha1 jnks kcne4 nnat pias1 ptgds ptpn2 rabgap1 rusc2 shank1 sumo1 sypl1 tkt topbp1 znf668
Tagcloud (Intersection) ?