MPO and CP

Number of citations of the paper that reports this interaction (PMID 9097926)
16

Data Source:
HPRD (in vitro)

		MPO	CP
Gene Name		myeloperoxidase	ceruloplasmin (ferroxidase)
Image
Gene Ontology Annotations	Cellular Component	Extracellular Space Nucleus Mitochondrion Lysosome Secretory Granule Azurophil Granule Extracellular Vesicular Exosome	Extracellular Region Extracellular Space Lysosomal Membrane Extracellular Vesicular Exosome Blood Microparticle
	Molecular Function	Chromatin Binding Peroxidase Activity Heparin Binding Heme Binding Metal Ion Binding	Ferroxidase Activity Copper Ion Binding Chaperone Binding
	Biological Process	Response To Yeast Hypochlorous Acid Biosynthetic Process Respiratory Burst Involved In Defense Response Defense Response Response To Oxidative Stress Aging Response To Mechanical Stimulus Removal Of Superoxide Radicals Response To Food Response To Lipopolysaccharide Low-density Lipoprotein Particle Remodeling Hydrogen Peroxide Catabolic Process Negative Regulation Of Apoptotic Process Negative Regulation Of Growth Of Symbiont In Host Defense Response To Fungus Oxidation-reduction Process Response To Gold Nanoparticle	Copper Ion Transport Cellular Iron Ion Homeostasis Transmembrane Transport Oxidation-reduction Process
Pathways			Metal ion SLC transporters Iron uptake and transport Transport of glucose and other sugars, bile salts and organic acids, metal ions and amine compounds SLC-mediated transmembrane transport
Drugs		Mesalazine Cefdinir L-Carnitine Melatonin Nomifensine	Drotrecogin alfa
Diseases
GWAS		Circulating myeloperoxidase levels (plasma) ( 23620142)	Subcutaneous adipose tissue ( 22589738)
Protein-Protein Interactions		1 interactors: CP	8 interactors: ATP7A BTRC GAST LTF MPO PLG PROC UBC
Entrez ID		4353	1356
HPRD ID		06102	00317
Ensembl ID		ENSG00000005381	ENSG00000047457
Uniprot IDs		P05164	A5PL27 P00450
PDB IDs		1CXP 1D2V 1D5L 1D7W 1DNU 1DNW 1MHL 1MYP 3F9P 3ZS0 3ZS1 4DL1 4EJX	1KCW 2J5W 4EJX 4ENZ
Enriched GO Terms of Interacting Partners?		Copper Ion Transport Cellular Iron Ion Homeostasis Iron Ion Homeostasis Transition Metal Ion Homeostasis	Negative Regulation Of Apoptotic Process Negative Regulation Of Programmed Cell Death Negative Regulation Of Cell Death Immune System Process Removal Of Superoxide Radicals Cellular Response To Superoxide Response To Superoxide Defense Response To Fungus Response To Oxygen Radical Regulation Of Apoptotic Process Regulation Of I-kappaB Kinase/NF-kappaB Signaling Proteolysis Regulation Of Cell Death Response To Fungus Superoxide Metabolic Process Regulation Of Sequence-specific DNA Binding Transcription Factor Activity Negative Regulation Of Blood Coagulation Negative Regulation Of Coagulation Positive Regulation Of Ubiquitin-protein Ligase Activity Involved In Regulation Of Mitotic Cell Cycle Transition Regulation Of Ubiquitin-protein Ligase Activity Involved In Mitotic Cell Cycle Response To Stress Negative Regulation Of Wound Healing Response To Stimulus Anaphase-promoting Complex-dependent Proteasomal Ubiquitin-dependent Protein Catabolic Process Positive Regulation Of Ubiquitin-protein Transferase Activity Positive Regulation Of Ligase Activity Iron Assimilation By Chelation And Transport Hypochlorous Acid Biosynthetic Process Negative Regulation Of Tumor Necrosis Factor (ligand) Superfamily Member 11 Production Elastin Biosynthetic Process Plasma Membrane Copper Ion Transport Positive Regulation Of Protein Ubiquitination Involved In Ubiquitin-dependent Protein Catabolic Process Regulation Of Ubiquitin-protein Transferase Activity Regulation Of Protein Ubiquitination Involved In Ubiquitin-dependent Protein Catabolic Process Regulation Of Blood Coagulation Cellular Response To Reactive Oxygen Species Reactive Oxygen Species Metabolic Process Proteolysis Involved In Cellular Protein Catabolic Process Tissue Remodeling Negative Regulation Of Single-species Biofilm Formation In Or On Host Organism Antifungal Humoral Response Positive Regulation Of Bone Mineralization Involved In Bone Maturation Positive Regulation Of Chondrocyte Proliferation Copper Ion Export Negative Regulation Of Osteoclast Development Response To Gold Nanoparticle Positive Regulation Of Transferase Activity Cellular Protein Catabolic Process G2/M Transition Of Mitotic Cell Cycle Regulation Of Body Fluid Levels
Tagcloud ?		anesthetized cd18 cecal cli create dawley duodenum exogenous gastrointestinal hypothesized icam incision infiltration integrins intercellular intra ligation mab mediator myeloperoxidase neutrophil paf saline separate sepsis sprague stomach urethan web	airways anesthetized artificially attacks breaths bronchoconstriction citric clarified counteracts endogenously gastroesophageal guinea halved hoe implication inhalation inhaled micromol nerves nk1 nk2 nmma reflux rl sr submaximum tachykinin tachykinins ventilated
Tagcloud (Difference) ?		cd18 cecal cli create dawley duodenum exogenous gastrointestinal hypothesized icam incision infiltration integrins intercellular intra ligation mab mediator myeloperoxidase neutrophil paf saline separate sepsis sprague stomach urethan web	airways artificially attacks breaths bronchoconstriction citric clarified counteracts endogenously gastroesophageal guinea halved hoe implication inhalation inhaled micromol nerves nk1 nk2 nmma reflux rl sr submaximum tachykinin tachykinins ventilated
Tagcloud (Intersection) ?		anesthetized