MARK3 and PMPCB

Number of citations of the paper that reports this interaction (PMID 16169070)
531

Data Source:
BioGRID (two hybrid)
HPRD (two hybrid)

		MARK3	PMPCB
Gene Name		MAP/microtubule affinity-regulating kinase 3	peptidase (mitochondrial processing) beta
Image			No pdb structure
Gene Ontology Annotations	Cellular Component	Plasma Membrane Extracellular Vesicular Exosome	Mitochondrial Inner Membrane Mitochondrial Matrix
	Molecular Function	Protein Serine/threonine Kinase Activity Protein Binding ATP Binding	Metalloendopeptidase Activity Metal Ion Binding
	Biological Process	Protein Phosphorylation	Proteolysis Protein Targeting To Mitochondrion Cellular Protein Metabolic Process
Pathways			Mitochondrial protein import
Drugs
Diseases
GWAS		Bone mineral density ( 22504420)
Protein-Protein Interactions		27 interactors: ANKRD7 ASB13 ATP6V0C CDC25C CHGB CPSF4 DYNLL1 FANCF HDAC7 KSR1 MAP2 MAPT MITF NOL11 PIM1 PKP2 PMPCB PNPLA2 PRKCQ SAAL1 SFN TCEA2 TTR VPS11 YWHAG YWHAQ YWHAZ	3 interactors: FXN MARK3 PMPCA
Entrez ID		4140	9512
HPRD ID		04058	07539
Ensembl ID		ENSG00000075413	ENSG00000105819
Uniprot IDs		P27448 Q86U11	B3KM34 E7ERZ4 O75439 Q96CP5
PDB IDs		2QNJ 3FE3
Enriched GO Terms of Interacting Partners?		Positive Regulation Of Protein Insertion Into Mitochondrial Membrane Involved In Apoptotic Signaling Pathway Positive Regulation Of Mitochondrial Outer Membrane Permeabilization Involved In Apoptotic Signaling Pathway Regulation Of Mitochondrial Outer Membrane Permeabilization Involved In Apoptotic Signaling Pathway Positive Regulation Of Mitochondrion Organization Regulation Of Mitochondrion Organization Intrinsic Apoptotic Signaling Pathway Positive Regulation Of Apoptotic Signaling Pathway Positive Regulation Of Organelle Organization Apoptotic Process Positive Regulation Of Intracellular Transport Regulation Of Intracellular Transport Programmed Cell Death Cell Death Death Organelle Organization Apoptotic Signaling Pathway Regulation Of Organelle Organization Regulation Of Apoptotic Process Positive Regulation Of Transport Regulation Of Cellular Component Organization Regulation Of Cell Death Mitotic Cell Cycle Phase Transition Cell Cycle Phase Transition Regulation Of Cyclin-dependent Protein Serine/threonine Kinase Activity Positive Regulation Of Signal Transduction G2/M Transition Of Mitotic Cell Cycle Positive Regulation Of Apoptotic Process Multicellular Organismal Development Positive Regulation Of Programmed Cell Death Positive Regulation Of Cell Death System Development Intracellular Signal Transduction Regulation Of Cellular Localization Regulation Of Establishment Of Protein Localization Substantia Nigra Development Protein Targeting Regulation Of Protein Localization Developmental Process Cellular Response To Insulin Stimulus Neural Nucleus Development Signaling Anatomical Structure Development Regulation Of Phosphorylation Protein Targeting To Mitochondrion Regulation Of Cellular Process Cellular Component Disassembly Involved In Execution Phase Of Apoptosis Intracellular Protein Transport Cell Communication Negative Regulation Of Apoptotic Process Positive Regulation Of T-helper 2 Cell Activation	Regulation Of Ferrochelatase Activity Iron Incorporation Into Metallo-sulfur Cluster Proprioception Mitochondrion Organization Positive Regulation Of Metalloenzyme Activity Protein Autoprocessing Neuromuscular Process Controlling Posture Negative Regulation Of Release Of Cytochrome C From Mitochondria Negative Regulation Of Multicellular Organism Growth Iron-sulfur Cluster Assembly Heme Biosynthetic Process Negative Regulation Of Mitochondrion Organization Response To Iron Ion Porphyrin-containing Compound Biosynthetic Process Negative Regulation Of Organ Growth Positive Regulation Of Oxidoreductase Activity Heme Metabolic Process Positive Regulation Of Lyase Activity Adult Walking Behavior Cellular Protein Metabolic Process Porphyrin-containing Compound Metabolic Process Pigment Biosynthetic Process Cellular Response To Hydrogen Peroxide Aerobic Respiration Protein Targeting To Mitochondrion Oxidative Phosphorylation Protein Localization To Mitochondrion Regulation Of Oxidoreductase Activity
Tagcloud ?		acrylamide amiloride bbmv benzoyl border brush cariporide dihydro guanidine guanidino hnhe1 ic50 isopro isopropyl lap1 methane methylsulphonyl micromol nhe nhe1 nhe2 nhe3 ok opossum propenyl pylidene rbnhe2 s3226 sulphonate
Tagcloud (Difference) ?		acrylamide amiloride bbmv benzoyl border brush cariporide dihydro guanidine guanidino hnhe1 ic50 isopro isopropyl lap1 methane methylsulphonyl micromol nhe nhe1 nhe2 nhe3 ok opossum propenyl pylidene rbnhe2 s3226 sulphonate
Tagcloud (Intersection) ?