MAP1A and RAPGEF3

Number of citations of the paper that reports this interaction (PMID 15202935)
9

Data Source:
HPRD (in vivo, two hybrid, in vitro)

		MAP1A	RAPGEF3
Gene Name		microtubule-associated protein 1A	Rap guanine nucleotide exchange factor (GEF) 3
Image		No pdb structure	No pdb structure
Gene Ontology Annotations	Cellular Component	Cytosol Microtubule Microtubule Associated Complex	Plasma Membrane CAMP-dependent Protein Kinase Complex Endomembrane System Membrane Extracellular Vesicular Exosome
	Molecular Function	Structural Molecule Activity Protein Binding Microtubule Binding	Guanyl-nucleotide Exchange Factor Activity Protein Binding CAMP-dependent Protein Kinase Regulator Activity Rap Guanyl-nucleotide Exchange Factor Activity CAMP Binding
	Biological Process	Microtubule Cytoskeleton Organization Sensory Perception Of Sound	Angiogenesis Energy Reserve Metabolic Process Signal Transduction Blood Coagulation Cell Proliferation CAMP-mediated Signaling Platelet Activation Positive Regulation Of CAMP Catabolic Process Rap Protein Signal Transduction Positive Regulation Of Rap GTPase Activity Small Molecule Metabolic Process Positive Regulation Of Angiogenesis Regulation Of Protein Kinase Activity Regulation Of Insulin Secretion Positive Regulation Of Stress Fiber Assembly Establishment Of Endothelial Barrier Cellular Response To CAMP Regulation Of Actin Cytoskeleton Reorganization
Pathways			Glucagon-like Peptide-1 (GLP1) regulates insulin secretion Rap1 signalling Integration of energy metabolism Regulation of insulin secretion Integrin alphaIIb beta3 signaling Platelet activation, signaling and aggregation Platelet Aggregation (Plug Formation) Adaptive Immune System
Drugs		Estramustine
Diseases
GWAS
Protein-Protein Interactions		22 interactors: ACTA1 ACTG1 AP1G1 ARHGEF11 CACNB4 DISC1 DLG1 DLG2 DLG4 GRB2 HTR2A KCNMA1 MAP1B MAP1LC3A NXF1 NXF2 RAPGEF3 RAPGEF4 SPP1 TUBA4A TUBB UPF2	6 interactors: AP2B1 MAP1A PNMA1 RAP1A RAP2A RRAS2
Entrez ID		4130	10411
HPRD ID		02549	06928
Ensembl ID		ENSG00000166963	ENSG00000079337
Uniprot IDs		E9PGC8 P78559 Q504X9	O95398 Q99777
PDB IDs
Enriched GO Terms of Interacting Partners?		Movement Of Cell Or Subcellular Component Cellular Localization Receptor Localization To Synapse Response To External Stimulus Cytoskeleton Organization Axonogenesis Axon Development Protein Localization To Synapse Cell Morphogenesis Involved In Neuron Differentiation Chemotaxis Platelet Activation Cell-cell Signaling Developmental Process Axon Guidance Neuron Projection Morphogenesis Muscle Contraction Blood Coagulation Hemostasis Cell Morphogenesis Involved In Differentiation Muscle System Process Establishment Of Localization In Cell Generation Of Neurons Neuron Projection Development Response To Stimulus Cell Projection Morphogenesis Neurogenesis Cell Part Morphogenesis Locomotion Multicellular Organismal Development Regulation Of Body Fluid Levels Cell Differentiation Synaptic Transmission Wound Healing System Development Nervous System Development Receptor Clustering Transport Neuron Development Cell Development Smooth Muscle Contraction Nucleotide Phosphorylation Establishment Or Maintenance Of Cell Polarity Cell Activation MRNA Export From Nucleus Cytoplasmic Transport Cellular Metal Ion Homeostasis Response To Wounding Cell Morphogenesis Organelle Organization Intracellular Transport	Rap Protein Signal Transduction Ras Protein Signal Transduction Small GTPase Mediated Signal Transduction
Tagcloud ?		1b adapting apparently assign chain chains coimmunoprecipitation consisting cooh dimerize entire epitope filament flexible fragments harbor heavy homologous immunofluorescence light map1b maps microtubule microtubules nocodazole oligomerize tagged taxol transiently
Tagcloud (Difference) ?		1b adapting apparently assign chain chains coimmunoprecipitation consisting cooh dimerize entire epitope filament flexible fragments harbor heavy homologous immunofluorescence light map1b maps microtubule microtubules nocodazole oligomerize tagged taxol transiently
Tagcloud (Intersection) ?