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MAGEA11 and UBE2D4
Number of citations of the paper that reports this interaction (PMID
16189514
)
699
Data Source:
BioGRID
(two hybrid)
HPRD
(two hybrid)
MAGEA11
UBE2D4
Gene Name
melanoma antigen family A, 11
ubiquitin-conjugating enzyme E2D 4 (putative)
Image
No pdb structure
No pdb structure
Gene Ontology Annotations
Cellular Component
Nucleus
Nucleoplasm
Cytoplasm
Molecular Function
Protein Binding
Ubiquitin-protein Transferase Activity
Protein Binding
ATP Binding
Ligase Activity
Ubiquitin Conjugating Enzyme Activity
Biological Process
Protein Ubiquitination
Protein K29-linked Ubiquitination
Protein K27-linked Ubiquitination
Protein K63-linked Ubiquitination
Protein K48-linked Ubiquitination
Protein K11-linked Ubiquitination
Protein K6-linked Ubiquitination
Pathways
Antigen processing: Ubiquitination & Proteasome degradation
Class I MHC mediated antigen processing & presentation
Adaptive Immune System
Drugs
Diseases
GWAS
Protein-Protein Interactions
86 interactors:
ACMSD
ACTN1
AKR1C3
ALDH5A1
AR
ARHGAP29
BCL2L11
BEX2
BIRC2
C18orf54
CCDC14
CCDC146
CCDC185
CDC20B
CDKN2B
CEP76
CLUAP1
COX7A2L
CSNK2A1
DIEXF
DNAJC10
DOCK10
ENOX2
EWSR1
FAM156A
GNPDA1
HOXB5
IL11
IL6ST
ILF3
JADE3
KIAA0408
LNX1
MAPK3
MCRS1
MED28
MGME1
MLF1
MTA1
MXD3
MYOZ1
NCOA2
NDEL1
NDUFAF1
NDUFB9
NIF3L1
NOL4
NOS3
NSUN4
OTUB2
PCBD2
PDE4B
PHYH
PIN4
PNKD
PNKP
POLR1D
PRDX3
PRKRIP1
PSMF1
RADIL
RBM23
SH2D4A
SNX20
SNX7
STAR
TCEA2
TCEANC
TCF25
TEX37
THEM5
TMEM123
TPM3
TRIM27
TRIM51
TRMT1
TXN2
UBE2D4
USP20
VTA1
WDYHV1
WTAP
ZBTB16
ZCCHC12
ZNF655
ZSWIM2
90 interactors:
AMFR
ARIH2
BFAR
BIRC8
CADPS2
CHFR
CNOT4
DAZAP2
DTX1
DTX2
DTX3
DTX3L
DZIP3
INCA1
LRSAM1
MAGEA11
MAP3K1
MARCH3
MGRN1
MIB1
MID1
MID2
MKRN2
MKRN3
MUL1
MYBL2
MYLIP
OTUB1
PHF7
PJA2
RBCK1
RCHY1
RFWD3
RING1
RLIM
RMND5B
RNF10
RNF103
RNF11
RNF111
RNF114
RNF115
RNF125
RNF126
RNF13
RNF130
RNF138
RNF14
RNF150
RNF165
RNF166
RNF167
RNF181
RNF185
RNF2
RNF25
RNF26
RNF38
RNF4
RNF43
RNF5
RNF7
SIAH1
TOPORS
TRAF6
TRAF7
TRIM10
TRIM17
TRIM2
TRIM25
TRIM27
TRIM3
TRIM31
TRIM35
TRIM38
TRIM39
TRIM43
TRIM45
TRIM5
TRIM50
TRIM8
UBE4A
UBOX5
UBTD1
UFM1
UHRF2
XIAP
ZNRF1
ZNRF2
ZNRF4
Entrez ID
4110
51619
HPRD ID
02281
14242
Ensembl ID
ENSG00000185247
ENSG00000078967
Uniprot IDs
G5E962
P43364
Q9Y2X8
PDB IDs
Enriched GO Terms of Interacting Partners
?
Cellular Nitrogen Compound Metabolic Process
Nitrogen Compound Metabolic Process
Heterocycle Metabolic Process
Cellular Aromatic Compound Metabolic Process
Cellular Metabolic Process
RNA Metabolic Process
Nucleobase-containing Compound Metabolic Process
Transcription, DNA-templated
RNA Biosynthetic Process
Regulation Of Metabolic Process
Cellular Process
Positive Regulation Of Metabolic Process
Gene Expression
Biosynthetic Process
Regulation Of Cellular Protein Metabolic Process
Catabolic Process
Regulation Of Nitrogen Compound Metabolic Process
Regulation Of Apoptotic Process
Metabolic Process
Protein Polyubiquitination
Negative Regulation Of Cellular Protein Metabolic Process
Cellular Macromolecule Biosynthetic Process
Negative Regulation Of Cellular Metabolic Process
Testosterone Biosynthetic Process
Regulation Of Cell Death
Macromolecule Biosynthetic Process
Regulation Of Gene Expression
Positive Regulation Of Cellular Metabolic Process
Regulation Of RNA Metabolic Process
Regulation Of Protein Metabolic Process
Rhythmic Process
Cell Death
Response To Lipopolysaccharide
Death
Negative Regulation Of Protein Metabolic Process
Respiratory Electron Transport Chain
Response To Molecule Of Bacterial Origin
Regulation Of Cell Cycle
Electron Transport Chain
Oxidation-reduction Process
Negative Regulation Of Catalytic Activity
RNA Methylation
Histone H4-K5 Acetylation
Histone H4-K8 Acetylation
Apoptotic Process
Reproductive Structure Development
Positive Regulation Of Gene Expression
Reproductive System Development
Negative Regulation Of Mitotic Cell Cycle Phase Transition
Programmed Cell Death
Protein Modification By Small Protein Conjugation
Protein Ubiquitination
Cellular Protein Modification Process
Cellular Protein Metabolic Process
Protein Metabolic Process
Protein Polyubiquitination
Protein Autoubiquitination
Cellular Metabolic Process
Ubiquitin-dependent Protein Catabolic Process
Modification-dependent Protein Catabolic Process
Protein Catabolic Process
Proteolysis Involved In Cellular Protein Catabolic Process
Cellular Protein Catabolic Process
Cellular Macromolecule Catabolic Process
Protein K63-linked Ubiquitination
Regulation Of Viral Entry Into Host Cell
Protein K48-linked Ubiquitination
Regulation Of Viral Release From Host Cell
Negative Regulation Of Viral Release From Host Cell
Negative Regulation Of Viral Entry Into Host Cell
Metabolic Process
Negative Regulation Of Viral Process
Catabolic Process
Proteolysis
Protein Ubiquitination Involved In Ubiquitin-dependent Protein Catabolic Process
Positive Regulation Of Sequence-specific DNA Binding Transcription Factor Activity
Regulation Of Viral Process
Protein Monoubiquitination
Positive Regulation Of NF-kappaB Transcription Factor Activity
Regulation Of Sequence-specific DNA Binding Transcription Factor Activity
Proteasome-mediated Ubiquitin-dependent Protein Catabolic Process
Proteasomal Protein Catabolic Process
Positive Regulation Of I-kappaB Kinase/NF-kappaB Signaling
Positive Regulation Of Signal Transduction
Negative Regulation Of Viral Transcription
Regulation Of I-kappaB Kinase/NF-kappaB Signaling
Cellular Process
Regulation Of Signal Transduction
Innate Immune Response
Interferon-gamma-mediated Signaling Pathway
Regulation Of Protein Ubiquitination
Cellular Response To Interferon-gamma
Regulation Of Signaling
Positive Regulation Of Intracellular Signal Transduction
Apoptotic Process
Response To Interferon-gamma
Programmed Cell Death
Cell Death
Death
Histone Monoubiquitination
Tagcloud
?
accumulation
apoptosis
apoptotic
arsenic
cadmium
conjugating
degradation
downregulation
elevated
enzymes
family
hand
induce
inorganic
mercury
p53
promote
proteasomal
proximal
rat
suppressed
suppression
tubular
ubiquitin
ubiquitination
Tagcloud (Difference)
?
accumulation
apoptosis
apoptotic
arsenic
cadmium
conjugating
degradation
downregulation
elevated
enzymes
family
hand
induce
inorganic
mercury
p53
promote
proteasomal
proximal
rat
suppressed
suppression
tubular
ubiquitin
ubiquitination
Tagcloud (Intersection)
?