LMX1B and SSBP3

Number of citations of the paper that reports this interaction (PMID 20211142)
148

Data Source:
BioGRID (two hybrid)

		LMX1B	SSBP3
Gene Name		LIM homeobox transcription factor 1, beta	single stranded DNA binding protein 3
Image		No pdb structure	No pdb structure
Gene Ontology Annotations	Cellular Component	Nucleus	Nucleus Protein Complex
	Molecular Function	Sequence-specific DNA Binding Transcription Factor Activity Protein Binding Zinc Ion Binding Sequence-specific DNA Binding	Single-stranded DNA Binding
	Biological Process	In Utero Embryonic Development Neuron Migration Trabecular Meshwork Development Transcription, DNA-templated Regulation Of Transcription, DNA-templated Multicellular Organismal Development Cell Proliferation Dorsal/ventral Pattern Formation Cerebellum Morphogenesis Central Nervous System Neuron Development Neuron Differentiation Collagen Fibril Organization Midbrain Development Limb Morphogenesis Organ Growth Positive Regulation Of Transcription From RNA Polymerase II Promoter Dopaminergic Neuron Differentiation	Hematopoietic Progenitor Cell Differentiation Transcription, DNA-templated Protein Complex Assembly Positive Regulation Of Cell Proliferation Prechordal Plate Formation Midbrain-hindbrain Boundary Initiation Positive Regulation Of Transcription From RNA Polymerase II Promoter Head Morphogenesis Positive Regulation Of Anterior Head Development
Pathways
Drugs
Diseases
GWAS		Body mass index ( 20935630)
Protein-Protein Interactions		4 interactors: APP LDB1 SSBP3 TCF3	16 interactors: ANKEF1 APP ARNT2 EWSR1 HCLS1 IL36RN LDB1 LDB2 LMX1B NXT2 PIN1 RFC1 SUPT5H TBC1D23 YES1 ZNF226
Entrez ID		4010	23648
HPRD ID		03986	09578
Ensembl ID		ENSG00000136944	ENSG00000157216
Uniprot IDs		B7ZLH2 O60663 Q6ISE0	Q9BWW4
PDB IDs
Enriched GO Terms of Interacting Partners?		Brain Development Head Development Central Nervous System Development Positive Regulation Of Transcription From RNA Polymerase II Promoter Anterior/posterior Pattern Specification Positive Regulation Of Transcription, DNA-templated Positive Regulation Of Macromolecule Biosynthetic Process Positive Regulation Of Gene Expression Histone H3 Acetylation Positive Regulation Of Cellular Biosynthetic Process Pattern Specification Process Regulation Of Transcription From RNA Polymerase II Promoter Somatic Stem Cell Maintenance Anterior/posterior Axis Specification Nervous System Development Anatomical Structure Morphogenesis Negative Regulation Of Cell Differentiation Histone Acetylation Axis Specification Internal Peptidyl-lysine Acetylation Positive Regulation Of Cellular Metabolic Process Peptidyl-lysine Acetylation Internal Protein Amino Acid Acetylation Histone H3-K4 Acetylation Midbrain-hindbrain Boundary Initiation Prechordal Plate Formation Transcription-dependent Tethering Of RNA Polymerase II Gene DNA At Nuclear Periphery Protein Acetylation Stem Cell Maintenance Organ Development Positive Regulation Of Hemoglobin Biosynthetic Process Synaptic Growth At Neuromuscular Junction Positive Regulation Of Anterior Head Development RNA Metabolic Process Embryo Development Cell Differentiation Positive Regulation Of Metabolic Process Gene Expression Collateral Sprouting In Absence Of Injury Positive Regulation Of Transcription From RNA Polymerase II Promoter During Mitosis Regulation Of Mitotic Cell Cycle Phase Transition Skin Development Regulation Of Cell Cycle Phase Transition Neural Plate Anterior/posterior Regionalization Stem Cell Development Peptidyl-lysine Modification Collateral Sprouting Axon Midline Choice Point Recognition Regulation Of Hemoglobin Biosynthetic Process Wnt Signaling Pathway	Positive Regulation Of Transcription, DNA-templated Positive Regulation Of Macromolecule Biosynthetic Process Positive Regulation Of Transcription From RNA Polymerase II Promoter Positive Regulation Of Gene Expression Positive Regulation Of Cellular Biosynthetic Process Regulation Of Transcription From RNA Polymerase II Promoter Positive Regulation Of Cellular Metabolic Process Positive Regulation Of Metabolic Process Regulation Of Transcription, DNA-templated Regulation Of Nucleic Acid-templated Transcription Regulation Of RNA Biosynthetic Process Regulation Of RNA Metabolic Process Epithelial Structure Maintenance Regulation Of Gene Expression Regulation Of Metabolic Process Regulation Of Nitrogen Compound Metabolic Process Transcription, DNA-templated RNA Metabolic Process RNA Biosynthetic Process Cerebellum Morphogenesis Gene Expression Regulation Of Cellular Process Regulation Of DNA-templated Transcription, Elongation Hindbrain Morphogenesis Histone H3-K4 Acetylation Negative Regulation Of Interferon-gamma Secretion Transcription-dependent Tethering Of RNA Polymerase II Gene DNA At Nuclear Periphery Somatic Stem Cell Maintenance Brain Development Negative Regulation Of Cellular Metabolic Process Homeostatic Process Head Development Innate Immune Response Antifungal Humoral Response Synaptic Growth At Neuromuscular Junction Single Stranded Viral RNA Replication Via Double Stranded DNA Intermediate Trabecular Meshwork Development Positive Regulation Of Hemoglobin Biosynthetic Process Hair Follicle Development Hair Cycle Process Collateral Sprouting In Absence Of Injury Regulation Of Interleukin-6 Production Hair Cycle Cerebellum Development Regulation Of Receptor Activity Central Nervous System Development Metencephalon Development Response To Organic Substance Collateral Sprouting Axon Midline Choice Point Recognition
Tagcloud ?		aer alternatives assure axes brief brought clues complements congenital correct deciphering deformity digit ectoderm en1 eventually fgfs limb limbs malformation manners modules organized p63 quantity shh sterile wnt7a zpa	applicable biogenesis btb btbd9 clones crlf3 detail easily elusive head legs microvesicles morphogenesis morphology nervous pc12 phenotypes pheochromocytoma poz restless slmvs stranded synaptic theoretically transport trapped uncovering vesicle vesicles
Tagcloud (Difference) ?		aer alternatives assure axes brief brought clues complements congenital correct deciphering deformity digit ectoderm en1 eventually fgfs limb limbs malformation manners modules organized p63 quantity shh sterile wnt7a zpa	applicable biogenesis btb btbd9 clones crlf3 detail easily elusive head legs microvesicles morphogenesis morphology nervous pc12 phenotypes pheochromocytoma poz restless slmvs stranded synaptic theoretically transport trapped uncovering vesicle vesicles
Tagcloud (Intersection) ?