ARHGAP1 and BAI2

Number of citations of the paper that reports this interaction (PMID 14697242)
13

Data Source:
HPRD (two hybrid)

		ARHGAP1	BAI2
Gene Name		Rho GTPase activating protein 1	brain-specific angiogenesis inhibitor 2
Image			No pdb structure
Gene Ontology Annotations	Cellular Component	Ruffle Cytosol Plasma Membrane Extracellular Vesicular Exosome	Plasma Membrane Integral Component Of Membrane
	Molecular Function	SH3/SH2 Adaptor Activity Rho GTPase Activator Activity Protein Binding SH3 Domain Binding Rac GTPase Activator Activity	G-protein Coupled Receptor Activity
	Biological Process	Small GTPase Mediated Signal Transduction Rho Protein Signal Transduction Positive Regulation Of Signal Transduction Positive Regulation Of Rac GTPase Activity Regulation Of Small GTPase Mediated Signal Transduction	G-protein Coupled Receptor Signaling Pathway Peripheral Nervous System Development Negative Regulation Of Angiogenesis
Pathways		Rho GTPase cycle Signaling by Rho GTPases
Drugs
Diseases
GWAS		Bone mineral density ( 22504420) Bone mineral density (hip) ( 19801982)
Protein-Protein Interactions		21 interactors: BAI2 BNIP2 BNIPL CDC42 CHEK2 EPB41L1 HMGCR HSP90AB1 ITPR1 KIF1B PIK3R1 PTPN11 RAC1 RASA1 RHOA RHOC SMARCD3 SRC TAX1BP1 TUBA4A WAS	8 interactors: ARHGAP1 GABPB1 HDHD2 LRP2BP SHANK1 SHANK2 SNTA1 STARD13
Entrez ID		392	576
HPRD ID		04108	04063
Ensembl ID		ENSG00000175220	ENSG00000121753
Uniprot IDs		Q07960	O60241
PDB IDs		1AM4 1GRN 1OW3 1RGP 1TX4 2NGR
Enriched GO Terms of Interacting Partners?		Vascular Endothelial Growth Factor Receptor Signaling Pathway Wound Healing Blood Coagulation Fc Receptor Signaling Pathway Hemostasis Fc-gamma Receptor Signaling Pathway Involved In Phagocytosis Fc-gamma Receptor Signaling Pathway Fc Receptor Mediated Stimulatory Signaling Pathway Response To Wounding Ephrin Receptor Signaling Pathway Immune Response-regulating Cell Surface Receptor Signaling Pathway Regulation Of Body Fluid Levels Axon Guidance Phagocytosis Immune Response-activating Cell Surface Receptor Signaling Pathway Immune Response-regulating Signaling Pathway T Cell Costimulation Axonogenesis Movement Of Cell Or Subcellular Component Innate Immune Response Platelet Activation Axon Development Cell Morphogenesis Involved In Neuron Differentiation Neurotrophin TRK Receptor Signaling Pathway Chemotaxis Neurotrophin Signaling Pathway Regulation Of Protein Transport Neuron Projection Morphogenesis Apoptotic Process Transmembrane Receptor Protein Tyrosine Kinase Signaling Pathway Regulation Of Establishment Of Protein Localization Regulation Of Phosphatidylinositol 3-kinase Activity Programmed Cell Death Cell Morphogenesis Involved In Differentiation Cell Death Death Regulation Of Lipid Kinase Activity Regulation Of Protein Localization Cytoskeleton Organization Positive Regulation Of Intracellular Signal Transduction Neuron Projection Development Generation Of Neurons Epidermal Growth Factor Receptor Signaling Pathway ERBB Signaling Pathway Cell Projection Morphogenesis Developmental Process Cell Part Morphogenesis Regulation Of Immune Response Neurogenesis Locomotion	Vocalization Behavior Synapse Organization Social Behavior Regulation Of Vasoconstriction By Circulating Norepinephrine Determination Of Affect Memory Learning Sensory Processing Habituation Adult Behavior Nonassociative Learning Negative Regulation Of Peptidyl-cysteine S-nitrosylation Righting Reflex Synapse Maturation Olfactory Behavior Learning Or Memory Regulation Of Membrane Potential Cognition Cytoskeletal Anchoring At Plasma Membrane Dendritic Spine Morphogenesis Negative Regulation Of Actin Filament Bundle Assembly Regulation Of Ventricular Cardiac Muscle Cell Membrane Repolarization Chemosensory Behavior Long Term Synaptic Depression Dendritic Spine Development Protein Localization To Synapse Regulation Of Actin Filament-based Process Regulation Of Alpha-amino-3-hydroxy-5-methyl-4-isoxazole Propionate Selective Glutamate Receptor Activity Ventricular Cardiac Muscle Cell Action Potential Regulation Of Ion Transmembrane Transport Dendritic Spine Organization Reflex Regulation Of Membrane Repolarization Regulation Of Signaling Single-organism Behavior Positive Regulation Of Dendritic Spine Development Exploration Behavior Cardiac Muscle Cell Action Potential Involved In Contraction Positive Regulation Of Excitatory Postsynaptic Membrane Potential Regulation Of Sodium Ion Transmembrane Transport Cardiac Muscle Cell Action Potential
Tagcloud ?		al7a1 c25h16orf71 conceptus ddx58 degs endometria ensbtat00000050193 estrus f2rl2 fbxl7 herc6 ifi16 ifnt insemination lims2 loc507810 mgc127874 mgc128929 parp12 rnaseq rnf213 samd9 serbp1 srgap2 tbc1d1 wbscr17 znfx1 zswim4 zxfx1	aza bex1 bisulfite candidate ccnd2 cdkn2a cobra colony cultures demethylating deoxycytidine ectopic ependymoma epigenetic epigenetically hypermethylation inactivation intracranial methylated microarray paediatric pharmacological restriction silenced silencing supports tumourigenesis unmasking wnt
Tagcloud (Difference) ?		al7a1 c25h16orf71 conceptus ddx58 degs endometria ensbtat00000050193 estrus f2rl2 fbxl7 herc6 ifi16 ifnt insemination lims2 loc507810 mgc127874 mgc128929 parp12 rnaseq rnf213 samd9 serbp1 srgap2 tbc1d1 wbscr17 znfx1 zswim4 zxfx1	aza bex1 bisulfite candidate ccnd2 cdkn2a cobra colony cultures demethylating deoxycytidine ectopic ependymoma epigenetic epigenetically hypermethylation inactivation intracranial methylated microarray paediatric pharmacological restriction silenced silencing supports tumourigenesis unmasking wnt
Tagcloud (Intersection) ?