KRT18 and BBS7

Number of citations of the paper that reports this interaction (PMID 18000879)
5

Data Source:
BioGRID (two hybrid)

		KRT18	BBS7
Gene Name		keratin 18, type I	Bardet-Biedl syndrome 7
Image		No pdb structure	No pdb structure
Gene Ontology Annotations	Cellular Component	Nucleolus Cytoplasm Microtubule Organizing Center Intermediate Filament Centriolar Satellite Keratin Filament Perinuclear Region Of Cytoplasm Extracellular Vesicular Exosome Cell Periphery	Nucleus Centrosome Cytosol Axoneme BBSome Ciliary Basal Body Ciliary Membrane
	Molecular Function	Structural Molecule Activity Protein Binding Poly(A) RNA Binding Scaffold Protein Binding	RNA Polymerase II Repressing Transcription Factor Binding Protein Binding
	Biological Process	Cell Cycle Anatomical Structure Morphogenesis Viral Process Tumor Necrosis Factor-mediated Signaling Pathway Golgi To Plasma Membrane CFTR Protein Transport Negative Regulation Of Apoptotic Process Intermediate Filament Cytoskeleton Organization Extrinsic Apoptotic Signaling Pathway Hepatocyte Apoptotic Process	Eye Development Heart Looping Regulation Of Transcription From RNA Polymerase II Promoter Organelle Organization Smoothened Signaling Pathway Determination Of Left/right Symmetry Brain Development Visual Perception Protein Transport Melanosome Transport Positive Regulation Of Proteasomal Ubiquitin-dependent Protein Catabolic Process Nonmotile Primary Cilium Assembly Fat Cell Differentiation Digestive Tract Morphogenesis Pigment Granule Aggregation In Cell Center Palate Development Limb Development Cilium Morphogenesis
Pathways			Cargo trafficking to the periciliary membrane Organelle biogenesis and maintenance Assembly of the primary cilium BBSome-mediated cargo-targeting to cilium
Drugs
Diseases
GWAS
Protein-Protein Interactions		73 interactors: BBS1 BBS2 BBS4 BBS7 CAMK2A CASP3 CASP6 CASP7 CASP8 CBL CCDC146 CCDC85B CCNI CDC5L CDK1 COL17A1 DEDD DNAJB6 EGFR EP300 EXOC8 FRAT1 GIT2 GOLGA2 GRN HAUS1 HGS HRAS HSPA1A HSPA4 HSPA5 IKBKG KPNA2 KRT15 KRT5 KRT72 KRT8 LDOC1 MAPK14 NME7 ORC5 PDE4DIP PIAS4 PKD1 PKP2 PKP3 PNN POT1 PRKCA PRKCE RAF1 RHPN2 RPS6KA3 SERPINE1 SHC1 SMARCD1 SUMO1 SVIL TCHP TNFRSF1B TRADD TUBG1 TUBGCP4 TXN2 TXNDC11 UPF2 USH2A YTHDC1 YWHAB YWHAE YWHAG YWHAH YWHAZ	4 interactors: FHOD1 JUN KRT18 PAX2
Entrez ID		3875	55212
HPRD ID		01020	07399
Ensembl ID		ENSG00000111057	ENSG00000138686
Uniprot IDs		P05783	Q8IWZ6
PDB IDs
Enriched GO Terms of Interacting Partners?		Apoptotic Process Programmed Cell Death Cell Death Death Apoptotic Signaling Pathway Intrinsic Apoptotic Signaling Pathway Regulation Of Cell Death Regulation Of Protein Metabolic Process Cellular Response To Organic Substance Neurotrophin TRK Receptor Signaling Pathway Regulation Of Apoptotic Process Neurotrophin Signaling Pathway Regulation Of Cellular Protein Metabolic Process Response To Organic Substance Cellular Response To Growth Factor Stimulus Response To Growth Factor Cell Surface Receptor Signaling Pathway Epidermal Growth Factor Receptor Signaling Pathway Positive Regulation Of Protein Insertion Into Mitochondrial Membrane Involved In Apoptotic Signaling Pathway ERBB Signaling Pathway Cellular Component Assembly Positive Regulation Of Mitochondrial Outer Membrane Permeabilization Involved In Apoptotic Signaling Pathway Cell Communication Positive Regulation Of Cellular Protein Metabolic Process Membrane Organization Signal Transduction Positive Regulation Of Signal Transduction Regulation Of Mitochondrial Outer Membrane Permeabilization Involved In Apoptotic Signaling Pathway Signaling Transmembrane Receptor Protein Tyrosine Kinase Signaling Pathway Organelle Organization Innate Immune Response Fibroblast Growth Factor Receptor Signaling Pathway Regulation Of Signal Transduction Positive Regulation Of Protein Metabolic Process Positive Regulation Of Transport Anatomical Structure Development Mitotic Cell Cycle Regulation Of Cellular Component Organization Regulation Of Signaling Mitotic Cell Cycle Phase Transition Cellular Response To Fibroblast Growth Factor Stimulus Cell Cycle Phase Transition Enzyme Linked Receptor Protein Signaling Pathway Response To Fibroblast Growth Factor Developmental Process Defense Response Regulation Of Proteolysis Cellular Protein Localization Cellular Response To Stimulus	Optic Chiasma Development Golgi To Plasma Membrane CFTR Protein Transport Cellular Response To Potassium Ion Starvation Positive Regulation Of Optic Nerve Formation Response To Hydrogen Peroxide Negative Regulation Of Apoptotic Process Negative Regulation Of Programmed Cell Death Positive Regulation Of Epithelial Cell Proliferation Apoptotic Process Negative Regulation Of Cell Death Programmed Cell Death Positive Regulation Of Transcription From RNA Polymerase II Promoter Pronephric Field Specification Leading Edge Cell Differentiation Optic Nerve Structural Organization Negative Regulation Of Apoptotic Process Involved In Metanephric Collecting Duct Development Negative Regulation Of Apoptotic Process Involved In Metanephric Nephron Tubule Development Negative Regulation Of Mesenchymal Cell Apoptotic Process Involved In Metanephric Nephron Morphogenesis Positive Regulation Of Metanephric DCT Cell Differentiation Regulation Of Metanephros Size Negative Regulation Of Transcription From RNA Polymerase II Promoter In Response To Endoplasmic Reticulum Stress Cell Death Death Response To Reactive Oxygen Species Negative Regulation Of Cytolysis Kidney Rudiment Formation Response To Mechanical Stimulus Paramesonephric Duct Development Vestibulocochlear Nerve Formation Metanephric Nephron Tubule Formation Positive Regulation Of Mesenchymal To Epithelial Transition Involved In Metanephros Morphogenesis Negative Regulation Of Mesenchymal Cell Apoptotic Process Involved In Nephron Morphogenesis Regulation Of Kidney Size Positive Regulation Of Transcription, DNA-templated Positive Regulation Of Metanephric Glomerulus Development Nephric Duct Formation Metanephric Mesenchymal Cell Differentiation Regulation Of Epithelial Cell Proliferation Regulation Of Apoptotic Process Ureter Morphogenesis Metanephric Tubule Formation Ureter Maturation Positive Regulation Of Macromolecule Biosynthetic Process Positive Regulation Of Gene Expression Positive Regulation Of Monocyte Differentiation Mesodermal Cell Fate Specification Negative Regulation Of Mesenchymal Cell Apoptotic Process Involved In Metanephros Development Regulation Of Cell Death Aging Positive Regulation Of Cellular Biosynthetic Process
Tagcloud ?		actg2 adenomatous archived b4ganlt2 bank casp3 cdx1 cdx2 classifier cnn1 col1a1 custom ezr fsp1 genomelab hcellmarkerplex house hybridisation incorporates lgr5 ms4a12 muc2 mucin nox1 ntn1 polyp signatures slc9a2 vwf
Tagcloud (Difference) ?		actg2 adenomatous archived b4ganlt2 bank casp3 cdx1 cdx2 classifier cnn1 col1a1 custom ezr fsp1 genomelab hcellmarkerplex house hybridisation incorporates lgr5 ms4a12 muc2 mucin nox1 ntn1 polyp signatures slc9a2 vwf
Tagcloud (Intersection) ?