KRT18 and DNAJB6

Number of citations of the paper that reports this interaction (PMID 10954706)
14

Data Source:
HPRD (in vivo, two hybrid, in vitro)

		KRT18	DNAJB6
Gene Name		keratin 18, type I	DnaJ (Hsp40) homolog, subfamily B, member 6
Image		No pdb structure	No pdb structure
Gene Ontology Annotations	Cellular Component	Nucleolus Cytoplasm Microtubule Organizing Center Intermediate Filament Centriolar Satellite Keratin Filament Perinuclear Region Of Cytoplasm Extracellular Vesicular Exosome Cell Periphery	Nucleus Nucleoplasm Cytoplasm Cytosol Membrane Z Disc Perinuclear Region Of Cytoplasm
	Molecular Function	Structural Molecule Activity Protein Binding Poly(A) RNA Binding Scaffold Protein Binding	ATPase Activator Activity Protein Binding Heat Shock Protein Binding Unfolded Protein Binding Chaperone Binding
	Biological Process	Cell Cycle Anatomical Structure Morphogenesis Viral Process Tumor Necrosis Factor-mediated Signaling Pathway Golgi To Plasma Membrane CFTR Protein Transport Negative Regulation Of Apoptotic Process Intermediate Filament Cytoskeleton Organization Extrinsic Apoptotic Signaling Pathway Hepatocyte Apoptotic Process	Protein Folding Positive Regulation Of ATPase Activity Negative Regulation Of Cysteine-type Endopeptidase Activity Involved In Apoptotic Process Intermediate Filament Organization Negative Regulation Of Inclusion Body Assembly
Pathways
Drugs
Diseases
GWAS
Protein-Protein Interactions		73 interactors: BBS1 BBS2 BBS4 BBS7 CAMK2A CASP3 CASP6 CASP7 CASP8 CBL CCDC146 CCDC85B CCNI CDC5L CDK1 COL17A1 DEDD DNAJB6 EGFR EP300 EXOC8 FRAT1 GIT2 GOLGA2 GRN HAUS1 HGS HRAS HSPA1A HSPA4 HSPA5 IKBKG KPNA2 KRT15 KRT5 KRT72 KRT8 LDOC1 MAPK14 NME7 ORC5 PDE4DIP PIAS4 PKD1 PKP2 PKP3 PNN POT1 PRKCA PRKCE RAF1 RHPN2 RPS6KA3 SERPINE1 SHC1 SMARCD1 SUMO1 SVIL TCHP TNFRSF1B TRADD TUBG1 TUBGCP4 TXN2 TXNDC11 UPF2 USH2A YTHDC1 YWHAB YWHAE YWHAG YWHAH YWHAZ	6 interactors: APP BRMS1 KRT18 PIK3CA POLR1D USP8
Entrez ID		3875	10049
HPRD ID		01020	07107
Ensembl ID		ENSG00000111057	ENSG00000105993
Uniprot IDs		P05783	B4DN73 E9PH18 O75190
PDB IDs
Enriched GO Terms of Interacting Partners?		Apoptotic Process Programmed Cell Death Cell Death Death Apoptotic Signaling Pathway Intrinsic Apoptotic Signaling Pathway Regulation Of Cell Death Regulation Of Protein Metabolic Process Cellular Response To Organic Substance Neurotrophin TRK Receptor Signaling Pathway Regulation Of Apoptotic Process Neurotrophin Signaling Pathway Regulation Of Cellular Protein Metabolic Process Response To Organic Substance Cellular Response To Growth Factor Stimulus Response To Growth Factor Cell Surface Receptor Signaling Pathway Epidermal Growth Factor Receptor Signaling Pathway Positive Regulation Of Protein Insertion Into Mitochondrial Membrane Involved In Apoptotic Signaling Pathway ERBB Signaling Pathway Cellular Component Assembly Positive Regulation Of Mitochondrial Outer Membrane Permeabilization Involved In Apoptotic Signaling Pathway Cell Communication Positive Regulation Of Cellular Protein Metabolic Process Membrane Organization Signal Transduction Positive Regulation Of Signal Transduction Regulation Of Mitochondrial Outer Membrane Permeabilization Involved In Apoptotic Signaling Pathway Signaling Transmembrane Receptor Protein Tyrosine Kinase Signaling Pathway Organelle Organization Innate Immune Response Fibroblast Growth Factor Receptor Signaling Pathway Regulation Of Signal Transduction Positive Regulation Of Protein Metabolic Process Positive Regulation Of Transport Anatomical Structure Development Mitotic Cell Cycle Regulation Of Cellular Component Organization Regulation Of Signaling Mitotic Cell Cycle Phase Transition Cellular Response To Fibroblast Growth Factor Stimulus Cell Cycle Phase Transition Enzyme Linked Receptor Protein Signaling Pathway Response To Fibroblast Growth Factor Developmental Process Defense Response Regulation Of Proteolysis Cellular Protein Localization Cellular Response To Stimulus	Regulation Of Anoikis Regulation Of Multicellular Organism Growth Golgi To Plasma Membrane CFTR Protein Transport Hypomethylation Of CpG Island Synaptic Growth At Neuromuscular Junction Regulation Of Cellular Protein Metabolic Process Innate Immune Response Collateral Sprouting In Absence Of Injury Regulation Of Protein Metabolic Process Insulin Receptor Signaling Pathway Via Phosphatidylinositol 3-kinase Positive Regulation Of Anoikis Platelet Activation Collateral Sprouting Axon Midline Choice Point Recognition Apoptotic Process Programmed Cell Death Smooth Endoplasmic Reticulum Calcium Ion Homeostasis Regulation Of Genetic Imprinting Cell Death Death Axon Choice Point Recognition Positive Regulation Of Cellular Protein Metabolic Process Regulation Of Developmental Growth Neuron Remodeling Positive Regulation Of Protein Metabolic Process Negative Regulation Of Fibroblast Apoptotic Process Immune Response Defense Response Negative Regulation Of Anoikis Vesicle-mediated Transport Regulation Of Cellular Amino Acid Metabolic Process Regulation Of Apoptotic Process Termination Of RNA Polymerase III Transcription Transcription Elongation From RNA Polymerase III Promoter Cellular Protein Modification Process Protein K48-linked Deubiquitination Protein K63-linked Deubiquitination Blood Coagulation Cellular Copper Ion Homeostasis Hemostasis Regulation Of Cell Death Endomembrane System Organization Regulation Of DNA Methylation Regulation Of Fibroblast Apoptotic Process Hepatocyte Apoptotic Process Phosphatidylinositol-3-phosphate Biosynthetic Process Copper Ion Homeostasis Suckling Behavior Golgi To Plasma Membrane Protein Transport Regulation Of Cellular Ketone Metabolic Process
Tagcloud ?		actg2 adenomatous archived b4ganlt2 bank casp3 cdx1 cdx2 classifier cnn1 col1a1 custom ezr fsp1 genomelab hcellmarkerplex house hybridisation incorporates lgr5 ms4a12 muc2 mucin nox1 ntn1 polyp signatures slc9a2 vwf	alphab bag3 biomechanical carrying crystallin deformation desmin disability fhl fiber filamin hereditary mechanical mfms myoblasts myofibrillar myopathies myotilin physiologic plectin premature shear sporadic stiffness stretch trigger vcp vulnerability zasp
Tagcloud (Difference) ?		actg2 adenomatous archived b4ganlt2 bank casp3 cdx1 cdx2 classifier cnn1 col1a1 custom ezr fsp1 genomelab hcellmarkerplex house hybridisation incorporates lgr5 ms4a12 muc2 mucin nox1 ntn1 polyp signatures slc9a2 vwf	alphab bag3 biomechanical carrying crystallin deformation desmin disability fhl fiber filamin hereditary mechanical mfms myoblasts myofibrillar myopathies myotilin physiologic plectin premature shear sporadic stiffness stretch trigger vcp vulnerability zasp
Tagcloud (Intersection) ?