KRT14 and SUMO3

Number of citations of the paper that reports this interaction (PMID 21062750)
12

Data Source:
BioGRID (pull down)

		KRT14	SUMO3
Gene Name		keratin 14, type I	small ubiquitin-like modifier 3
Image
Gene Ontology Annotations	Cellular Component	Nucleus Cytoplasm Cytosol Intermediate Filament Keratin Filament Extracellular Vesicular Exosome Cell Periphery	Kinetochore Nucleus Nucleoplasm Cytoplasm PML Body Extracellular Vesicular Exosome
	Molecular Function	Structural Constituent Of Cytoskeleton Protein Binding Keratin Filament Binding	Protein Binding SUMO Transferase Activity
	Biological Process	Aging Epidermis Development Response To Zinc Ion Response To Ionizing Radiation Epithelial Cell Differentiation Hemidesmosome Assembly Cell Junction Assembly Hair Cycle Intermediate Filament Bundle Assembly	Protein Sumoylation Protein Localization To Nucleus Post-translational Protein Modification Cellular Protein Metabolic Process Positive Regulation Of Protein Ubiquitination Involved In Ubiquitin-dependent Protein Catabolic Process
Pathways		Cell junction organization Type I hemidesmosome assembly	SUMO is proteolytically processed Post-translational protein modification SUMOylation SUMO is conjugated to E1 (UBA2:SAE1) SUMO is transferred from E1 to E2 (UBE2I, UBC9) Processing and activation of SUMO
Drugs
Diseases
GWAS
Protein-Protein Interactions		10 interactors: APC DST HSPA5 KRT5 PKP1 SUMO1 SUMO2 SUMO3 TCHP TRADD	53 interactors: ANXA7 ARL13A ARNTL ATF3 ATF7IP BCL11A BLM CCNE2 CDKN1A CEBPA CHAF1A CUL3 FOS HSF1 HSF2 JUN KALRN KCNA5 KRT14 KRT5 KRT8 MAPKAPK3 NFKBIA PFDN1 PIAS1 PIAS2 PIAS3 PIAS4 PML RANGAP1 SAE1 SATB1 SENP1 SENP2 SENP5 SH3KBP1 SMN1 SOX10 SOX6 SP100 STAB2 STK24 TDG TDP2 TK1 TP53BP2 TTR UBA2 UBE2I UBE3A UPF2 USPL1 VIM
Entrez ID		3861	6612
HPRD ID		01017	03754
Ensembl ID		ENSG00000186847	ENSG00000184900
Uniprot IDs		P02533	B4DUW4 P55854
PDB IDs		3TNU	1U4A 2IO1
Enriched GO Terms of Interacting Partners?		Protein Sumoylation Positive Regulation Of Protein Catabolic Process Positive Regulation Of Protein Metabolic Process Regulation Of Proteolysis Positive Regulation Of Proteolysis Hemidesmosome Assembly Regulation Of Protein Catabolic Process Regulation Of Proteasomal Ubiquitin-dependent Protein Catabolic Process Positive Regulation Of Proteolysis Involved In Cellular Protein Catabolic Process Positive Regulation Of Cellular Protein Catabolic Process Positive Regulation Of Cellular Protein Metabolic Process Regulation Of Cellular Protein Metabolic Process Regulation Of Proteasomal Protein Catabolic Process Cell Junction Assembly Post-translational Protein Modification Regulation Of Protein Metabolic Process Intermediate Filament Cytoskeleton Organization Peptidyl-lysine Modification Intermediate Filament-based Process Cell-substrate Junction Assembly Cellular Component Disassembly Involved In Execution Phase Of Apoptosis Positive Regulation Of Proteasomal Ubiquitin-dependent Protein Catabolic Process Positive Regulation Of Proteasomal Protein Catabolic Process Execution Phase Of Apoptosis Regulation Of Protein Folding In Endoplasmic Reticulum Apoptotic Process Programmed Cell Death Cellular Component Assembly Cell Death Death Cerebellum Structural Organization Canonical Wnt Signaling Pathway Involved In Positive Regulation Of Apoptotic Process Protein Localization To Organelle Positive Regulation Of Metabolic Process Positive Regulation Of Protein Ubiquitination Cell Cycle Arrest Cellular Response To Cytokine Stimulus PML Body Organization Negative Regulation Of Odontogenesis Protein Modification By Small Protein Conjugation Positive Regulation Of Protein Complex Assembly Protein Localization To Nucleus Positive Regulation Of Cellular Metabolic Process Protein Localization To Nuclear Pore Intermediate Filament Bundle Assembly Response To Cytokine Protein Localization To Nuclear Envelope Metaphase/anaphase Transition Of Mitotic Cell Cycle Canonical Wnt Signaling Pathway Involved In Negative Regulation Of Apoptotic Process Regulation Of Protein Ubiquitination	Protein Sumoylation Positive Regulation Of Metabolic Process Peptidyl-lysine Modification Positive Regulation Of Gene Expression Regulation Of Transcription From RNA Polymerase II Promoter Positive Regulation Of Transcription, DNA-templated Positive Regulation Of Cellular Metabolic Process Negative Regulation Of Nucleic Acid-templated Transcription Negative Regulation Of RNA Biosynthetic Process Negative Regulation Of Gene Expression Positive Regulation Of Macromolecule Biosynthetic Process Negative Regulation Of Biosynthetic Process Regulation Of Metabolic Process Positive Regulation Of Cellular Biosynthetic Process Protein Modification By Small Protein Conjugation Negative Regulation Of Transcription, DNA-templated Negative Regulation Of Cellular Metabolic Process Regulation Of Gene Expression Positive Regulation Of Transcription From RNA Polymerase II Promoter Response To Stimulus Negative Regulation Of Transcription From RNA Polymerase II Promoter Anatomical Structure Development Regulation Of Nucleic Acid-templated Transcription Regulation Of RNA Biosynthetic Process Regulation Of RNA Metabolic Process Transcription, DNA-templated Regulation Of Transcription, DNA-templated Regulation Of Nitrogen Compound Metabolic Process Protein Desumoylation Cellular Metabolic Process Apoptotic Signaling Pathway RNA Biosynthetic Process Peptidyl-amino Acid Modification Developmental Process Apoptotic Process Programmed Cell Death Viral Process Transcription From RNA Polymerase II Promoter Cell Death Death RNA Metabolic Process Multicellular Organismal Development Response To Abiotic Stimulus System Development Regulation Of Cellular Process Cellular Response To Stimulus Cellular Response To Stress Regulation Of Cell Cycle Cellular Macromolecule Biosynthetic Process Nucleobase-containing Compound Metabolic Process
Tagcloud ?		amu arising carcinogenic chimera densely distinguished earth elicits esr1 faster grew grow hosts ionizing irradiated k14 k18 keratin krt18 mev oncology radiation sham si sparsely stroma syngeneic tended trp53	aphidicolin attachment break breakage budding cfs covalent excessive fields fragile hallmark modifier ortholog perturbed pol32 pold3 polypeptides proteomic recombinational replication resource rpa ssdna stresses subfamily sumo1 sumo2 sumoylation
Tagcloud (Difference) ?		amu arising carcinogenic chimera densely distinguished earth elicits esr1 faster grew grow hosts ionizing irradiated k14 k18 keratin krt18 mev oncology radiation sham si sparsely stroma syngeneic tended trp53	aphidicolin attachment break breakage budding cfs covalent excessive fields fragile hallmark modifier ortholog perturbed pol32 pold3 polypeptides proteomic recombinational replication resource rpa ssdna stresses subfamily sumo1 sumo2 sumoylation
Tagcloud (Intersection) ?