KPNA4 and TGM2

Number of citations of the paper that reports this interaction (PMID 10100610)
13

Data Source:
BioGRID (affinity chromatography technology)
HPRD (in vivo, in vitro, two hybrid)

		KPNA4	TGM2
Gene Name		karyopherin alpha 4 (importin alpha 3)	transglutaminase 2
Image		No pdb structure
Gene Ontology Annotations	Cellular Component	Nucleoplasm Cytosol Extracellular Vesicular Exosome	Mitochondrion Cytosol Plasma Membrane Focal Adhesion Extracellular Vesicular Exosome
	Molecular Function	Protein Binding Protein Transporter Activity	Protein-glutamine Gamma-glutamyltransferase Activity Protein Binding GTP Binding Protein Domain Specific Binding Metal Ion Binding
	Biological Process	NLS-bearing Protein Import Into Nucleus Cytokine-mediated Signaling Pathway Response To Hydrogen Peroxide	Blood Vessel Remodeling Isopeptide Cross-linking Via N6-(L-isoglutamyl)-L-lysine Negative Regulation Of Endoplasmic Reticulum Calcium Ion Concentration Positive Regulation Of Apoptotic Process Positive Regulation Of I-kappaB Kinase/NF-kappaB Signaling Apoptotic Cell Clearance Positive Regulation Of Cell Adhesion Positive Regulation Of Smooth Muscle Cell Proliferation Positive Regulation Of Inflammatory Response Protein Homooligomerization Positive Regulation Of Cytosolic Calcium Ion Concentration Involved In Phospholipase C-activating G-protein Coupled Signaling Pathway Positive Regulation Of Mitochondrial Calcium Ion Concentration Branching Involved In Salivary Gland Morphogenesis Salivary Gland Cavitation
Pathways		ISG15 antiviral mechanism Interferon Signaling Cytokine Signaling in Immune system Antiviral mechanism by IFN-stimulated genes
Drugs			Guanosine-5\'-Diphosphate
Diseases
GWAS
Protein-Protein Interactions		17 interactors: APP CDKN1B CSE1L CSNK2A1 CUL4B CYHR1 EXO1 HNRNPC KPNB1 MAT2B NUP50 PLAA RAC1 RCC1 RECQL TGM2 TP53	55 interactors: A2M ABCA1 ACTB ADAR ALDOA ANKRD28 ANXA1 APP ATF4 BNIP3 C3 CASP3 COL4A3BP CSNK2A2 EIF5A FN1 FNTA GCGR GRN GSTP1 HIST1H2BG HIST2H2BE HNRNPF HNRNPUL1 HP HSPA1A HSPA1B HSPA8 HTT ITGB1 ITGB3 KPNA3 KPNA4 LTBP1 MAP3K12 PAK1 PLCD1 PPHLN1 RB1 RELA RHOA S100A7 SERPINF2 SERTAD1 SIPA1L2 SLC7A9 SMAD2 SMAD3 SPARC SUMO1 TAB2 TMEM176A TMSB4X TUBB ZNF512B
Entrez ID		3840	7052
HPRD ID		04275	01825
Ensembl ID		ENSG00000186432	ENSG00000198959
Uniprot IDs		O00629	B4DIT7 F5H6P0 P21980
PDB IDs			1FAU 1KV3 2Q3Z 3LY6 3S3J 3S3P 3S3S
Enriched GO Terms of Interacting Partners?		Regulation Of Mitotic Cell Cycle Regulation Of Mitotic Cell Cycle Phase Transition Regulation Of Cell Cycle Phase Transition Regulation Of Cell Cycle Process Apoptotic Process Programmed Cell Death Cell Death Death Positive Regulation Of Cell Cycle Process Cell Cycle Cellular Response To Stimulus Regulation Of Cell Cycle Viral Process Positive Regulation Of Cell Cycle DNA Strand Renaturation Mitotic Cell Cycle Arrest Regulation Of Catalytic Activity Mitotic Cell Cycle Process Regulation Of G1/S Transition Of Mitotic Cell Cycle Regulation Of Cell Cycle G1/S Phase Transition Positive Regulation Of Protein Metabolic Process Mitotic Cell Cycle Negative Regulation Of Mitotic Cell Cycle Phase Transition Mitotic Cell Cycle Checkpoint Response To Stimulus Protein Import Into Nucleus, Translocation Nucleobase-containing Compound Metabolic Process Cellular Response To DNA Damage Stimulus Positive Regulation Of Protein Complex Assembly Apoptotic Cell Clearance Endoplasmic Reticulum Calcium Ion Homeostasis Regulation Of Organelle Organization Heterocycle Metabolic Process Cellular Aromatic Compound Metabolic Process Cellular Nitrogen Compound Metabolic Process Positive Regulation Of Protein Catabolic Process Negative Regulation Of Mitotic Cell Cycle Cell Surface Receptor Signaling Pathway Cell Cycle Process Cell Cycle Checkpoint DNA Metabolic Process Positive Regulation Of Apoptotic Process Positive Regulation Of Programmed Cell Death DNA Repair Response To Abiotic Stimulus Regulation Of Growth Positive Regulation Of Cell Death DNA Damage Response, Signal Transduction By P53 Class Mediator Resulting In Cell Cycle Arrest Signal Transduction Involved In Mitotic G1 DNA Damage Checkpoint Neuron Apoptotic Process	Response To Stress Response To External Stimulus Response To Stimulus Secretion By Cell Establishment Of Localization In Cell Platelet Degranulation Secretion Regulation Of Cellular Protein Metabolic Process Regulation Of Protein Metabolic Process Cellular Localization Positive Regulation Of Metabolic Process Platelet Activation Regulation Of Cell Proliferation Response To Wounding Regulation Of Signal Transduction Response To Other Organism Positive Regulation Of Cellular Metabolic Process Wound Healing Response To Biotic Stimulus Immune System Process Response To Oxidative Stress Blood Coagulation Response To Organic Substance Hemostasis Regulation Of Cellular Process Regulation Of Signaling Regulation Of Cellular Component Organization Defense Response Regulation Of Phosphorus Metabolic Process Regulation Of Immune System Process Cellular Response To Stimulus Cell Activation Regulation Of Catalytic Activity Signal Transduction Signaling Exocytosis Regulation Of Body Fluid Levels Positive Regulation Of Protein Metabolic Process Cell Communication Negative Regulation Of Protein Metabolic Process Cellular Response To Organic Substance Positive Regulation Of Cellular Protein Metabolic Process Cell Surface Receptor Signaling Pathway Regulation Of Phosphorylation Regulation Of Metabolic Process Viral Process Viral Entry Into Host Cell Entry Into Host Cell Regulation Of Protein Phosphorylation Response To Abiotic Stimulus
Tagcloud ?		9k arrb1 atg14 atg4b cage1 cald1 cd9 chrna7 chrnb1 col1 expressional fn1 frap hey1 humn il10r il12 il13 il15 il27 immunochemical informational oas slc6a2 vegfc villi villous villus voluntarily	antral atresia atretic bga build categorized cattle cct2 cyp11a1 cyp19a1 dab2 dairy dsg2 e2f1 follicle follicles follicular granulosa hybridized microarrays offers oocyte originating phases plateau segregation steroidogenesis transcriptomic ultimately
Tagcloud (Difference) ?		9k arrb1 atg14 atg4b cage1 cald1 cd9 chrna7 chrnb1 col1 expressional fn1 frap hey1 humn il10r il12 il13 il15 il27 immunochemical informational oas slc6a2 vegfc villi villous villus voluntarily	antral atresia atretic bga build categorized cattle cct2 cyp11a1 cyp19a1 dab2 dairy dsg2 e2f1 follicle follicles follicular granulosa hybridized microarrays offers oocyte originating phases plateau segregation steroidogenesis transcriptomic ultimately
Tagcloud (Intersection) ?