EIF6 and OS9

Number of citations of the paper that reports this interaction (PMID 16169070)
531

Data Source:
HPRD (two hybrid)

		EIF6	OS9
Gene Name		eukaryotic translation initiation factor 6	osteosarcoma amplified 9, endoplasmic reticulum lectin
Image		No pdb structure
Gene Ontology Annotations	Cellular Component	Nucleus Lamin Filament Nucleoplasm Nucleolus Cytoplasm Extracellular Vesicular Exosome	Hrd1p Ubiquitin Ligase Complex Endoplasmic Reticulum Lumen Endoplasmic Reticulum Quality Control Compartment
	Molecular Function	Translation Initiation Factor Activity Protein Binding Ribosome Binding Ribosomal Large Subunit Binding	Glycoprotein Binding Protease Binding Protein Binding Carbohydrate Binding
	Biological Process	Ribosomal Subunit Export From Nucleus Translational Initiation Mature Ribosome Assembly Ribosomal Large Subunit Biogenesis	Protein Targeting Protein Retention In ER Lumen Protein Ubiquitination ER-associated Ubiquitin-dependent Protein Catabolic Process Response To Endoplasmic Reticulum Stress Protein Ubiquitination Involved In Ubiquitin-dependent Protein Catabolic Process
Pathways			Hedgehog ligand biogenesis Processing-defective Hh variants abrogate ligand secretion Hh ligand biogenesis disease Signaling by Hedgehog
Drugs
Diseases
GWAS		Height ( 18391951)
Protein-Protein Interactions		38 interactors: ABCF1 ACAP3 ACTG1 AKT1S1 ALDH2 APP C4orf27 CLEC4G CRELD1 CSNK2B DHX58 EIF2AK2 ENOX1 FHL2 FUNDC2 GIT1 GNB2L1 HIP1 ITGB4 KIAA1377 LRIF1 MRPS31 OAS3 OFD1 OS9 PDHA1 PLK1 POLA2 PRKCB PSME1 RPL6 SEPT3 TK1 UPF3B USP33 WFS1 XRN2 ZBTB26	16 interactors: ACVR1B CPNE6 CREB3 DCSTAMP EGLN1 EGLN3 EIF6 FOXM1 HIF1A MEP1B RBX1 SMAD2 SNRPD2 SREBF2 TRPV4 ZNF512B
Entrez ID		3692	10956
HPRD ID		04221	17804
Ensembl ID		ENSG00000242372	ENSG00000135506
Uniprot IDs		P56537	B4E321 Q13438
PDB IDs			3AIH
Enriched GO Terms of Interacting Partners?		Positive Regulation Of Cellular Protein Metabolic Process Posttranscriptional Regulation Of Gene Expression Positive Regulation Of Proteolysis Catabolic Process Positive Regulation Of Protein Metabolic Process Regulation Of Cellular Protein Metabolic Process Cell Cycle Cellular Macromolecule Catabolic Process Proteasome-mediated Ubiquitin-dependent Protein Catabolic Process Proteasomal Protein Catabolic Process Regulation Of Protein Metabolic Process Regulation Of Proteolysis Regulation Of Translation Positive Regulation Of Peptidase Activity Regulation Of Protein Kinase Activity Mitotic Cell Cycle Regulation Of Signal Transduction Regulation Of Catalytic Activity Regulation Of Kinase Activity Regulation Of Metabolic Process Cell Projection Morphogenesis Cell Projection Organization Response To Stress Cell Part Morphogenesis Gene Expression Axon Guidance Regulation Of Signaling Positive Regulation Of Catalytic Activity Mitotic Cell Cycle Process Regulation Of Binding Negative Regulation Of Defense Response To Virus Mitotic Cell Cycle Phase Transition Cell Cycle Phase Transition Positive Regulation Of Hydrolase Activity Cell Cycle Process Regulation Of Cellular Ketone Metabolic Process Cell Morphogenesis Positive Regulation Of Metabolic Process Ubiquitin-dependent Protein Catabolic Process Regulation Of Protein Phosphorylation Modification-dependent Protein Catabolic Process Cellular Metabolic Process Positive Regulation Of Cellular Metabolic Process Negative Regulation Of Signal Transduction Negative Regulation Of Transferase Activity Axonogenesis Response To External Stimulus Positive Regulation Of Endopeptidase Activity Regulation Of Apoptotic Process Innate Immune Response	Regulation Of Transcription From RNA Polymerase II Promoter In Response To Hypoxia Regulation Of Transcription From RNA Polymerase II Promoter In Response To Stress Regulation Of DNA-templated Transcription In Response To Stress Cellular Response To Hypoxia Cellular Response To Decreased Oxygen Levels Regulation Of Transcription From RNA Polymerase II Promoter Cellular Response To Oxygen Levels Cellular Response To Stress Oxygen Homeostasis Positive Regulation Of Activin Receptor Signaling Pathway Positive Regulation Of Myeloid Cell Differentiation Peptidyl-proline Hydroxylation To 4-hydroxy-L-proline Positive Regulation Of Transcription From RNA Polymerase II Promoter Response To Hypoxia Regulation Of Growth Nodal Signaling Pathway Regulation Of Cell Growth Positive Regulation Of Erythrocyte Differentiation 4-hydroxyproline Metabolic Process Regulation Of Transcription, DNA-templated Regulation Of Activin Receptor Signaling Pathway Regulation Of Nucleic Acid-templated Transcription Regulation Of RNA Biosynthetic Process Response To Stress Regulation Of RNA Metabolic Process Positive Regulation Of Transcription, DNA-templated Peptidyl-proline Hydroxylation Protein Hydroxylation Activin Receptor Signaling Pathway Transcription From RNA Polymerase II Promoter Regulation Of Myeloid Cell Differentiation Heterocycle Metabolic Process Regulation Of Erythrocyte Differentiation Positive Regulation Of Macromolecule Biosynthetic Process Positive Regulation Of Transcription From RNA Polymerase II Promoter Involved In Cellular Response To Chemical Stimulus In Utero Embryonic Development Regulation Of Gene Expression Positive Regulation Of Gene Expression Regulation Of Nitrogen Compound Metabolic Process Positive Regulation Of Cellular Biosynthetic Process Negative Regulation Of Growth Negative Regulation Of Signal Transduction Response To Abiotic Stimulus Cellular Macromolecular Complex Assembly Cellular Response To Stimulus Negative Regulation Of Ligand-dependent Nuclear Receptor Transcription Coactivator Activity Cortical Microtubule Organization Osmosensory Signaling Pathway Neural Fold Elevation Formation Positive Regulation Of Cellular Metabolic Process
Tagcloud ?		40s 60s 80s associates biogenesis cerevisiae cessation depleted designated encodes imbalance lysates maps mer monosomes mr polyribosomes polysomal prevents ribosomal ribosomes saccharomyces stoichiometric subunits tif6 true ultimately xvi yeast	branch c57y calnexin calreticulin cnx constrained erad folded folding futile glc1man7glcnac2 glycan glycans glycoproteins harbours improperly interconnected kifunensine lectins mannosidases mns4 mns5 oligosaccharide sel1l sort stabilized strubbelig subex thaliana
Tagcloud (Difference) ?		40s 60s 80s associates biogenesis cerevisiae cessation depleted designated encodes imbalance lysates maps mer monosomes mr polyribosomes polysomal prevents ribosomal ribosomes saccharomyces stoichiometric subunits tif6 true ultimately xvi yeast	branch c57y calnexin calreticulin cnx constrained erad folded folding futile glc1man7glcnac2 glycan glycans glycoproteins harbours improperly interconnected kifunensine lectins mannosidases mns4 mns5 oligosaccharide sel1l sort stabilized strubbelig subex thaliana
Tagcloud (Intersection) ?