EIF6 and MRPS31

Number of citations of the paper that reports this interaction (PMID 16169070)
531

Data Source:
BioGRID (two hybrid)
HPRD (two hybrid)

		EIF6	MRPS31
Gene Name		eukaryotic translation initiation factor 6	mitochondrial ribosomal protein S31
Image		No pdb structure	No pdb structure
Gene Ontology Annotations	Cellular Component	Nucleus Lamin Filament Nucleoplasm Nucleolus Cytoplasm Extracellular Vesicular Exosome	Nucleolus Mitochondrion Mitochondrial Inner Membrane Mitochondrial Small Ribosomal Subunit
	Molecular Function	Translation Initiation Factor Activity Protein Binding Ribosome Binding Ribosomal Large Subunit Binding	Structural Constituent Of Ribosome Protein Binding Protein Domain Specific Binding Poly(A) RNA Binding
	Biological Process	Ribosomal Subunit Export From Nucleus Translational Initiation Mature Ribosome Assembly Ribosomal Large Subunit Biogenesis	Organelle Organization Mitochondrial Translation Mitochondrial Translational Initiation Mitochondrial Translational Elongation Mitochondrial Translational Termination
Pathways			Mitochondrial translation Organelle biogenesis and maintenance Mitochondrial translation elongation Mitochondrial translation initiation Mitochondrial translation termination
Drugs
Diseases
GWAS		Height ( 18391951)
Protein-Protein Interactions		38 interactors: ABCF1 ACAP3 ACTG1 AKT1S1 ALDH2 APP C4orf27 CLEC4G CRELD1 CSNK2B DHX58 EIF2AK2 ENOX1 FHL2 FUNDC2 GIT1 GNB2L1 HIP1 ITGB4 KIAA1377 LRIF1 MRPS31 OAS3 OFD1 OS9 PDHA1 PLK1 POLA2 PRKCB PSME1 RPL6 SEPT3 TK1 UPF3B USP33 WFS1 XRN2 ZBTB26	3 interactors: EIF6 LYST STAT3
Entrez ID		3692	10240
HPRD ID		04221	10098
Ensembl ID		ENSG00000242372	ENSG00000102738
Uniprot IDs		P56537	Q92665
PDB IDs
Enriched GO Terms of Interacting Partners?		Positive Regulation Of Cellular Protein Metabolic Process Posttranscriptional Regulation Of Gene Expression Positive Regulation Of Proteolysis Catabolic Process Positive Regulation Of Protein Metabolic Process Regulation Of Cellular Protein Metabolic Process Cell Cycle Cellular Macromolecule Catabolic Process Proteasome-mediated Ubiquitin-dependent Protein Catabolic Process Proteasomal Protein Catabolic Process Regulation Of Protein Metabolic Process Regulation Of Proteolysis Regulation Of Translation Positive Regulation Of Peptidase Activity Regulation Of Protein Kinase Activity Mitotic Cell Cycle Regulation Of Signal Transduction Regulation Of Catalytic Activity Regulation Of Kinase Activity Regulation Of Metabolic Process Cell Projection Morphogenesis Cell Projection Organization Response To Stress Cell Part Morphogenesis Gene Expression Axon Guidance Regulation Of Signaling Positive Regulation Of Catalytic Activity Mitotic Cell Cycle Process Regulation Of Binding Negative Regulation Of Defense Response To Virus Mitotic Cell Cycle Phase Transition Cell Cycle Phase Transition Positive Regulation Of Hydrolase Activity Cell Cycle Process Regulation Of Cellular Ketone Metabolic Process Cell Morphogenesis Positive Regulation Of Metabolic Process Ubiquitin-dependent Protein Catabolic Process Regulation Of Protein Phosphorylation Modification-dependent Protein Catabolic Process Cellular Metabolic Process Positive Regulation Of Cellular Metabolic Process Negative Regulation Of Signal Transduction Negative Regulation Of Transferase Activity Axonogenesis Response To External Stimulus Positive Regulation Of Endopeptidase Activity Regulation Of Apoptotic Process Innate Immune Response	Cytoplasmic Transport Endosome To Lysosome Transport Via Multivesicular Body Sorting Pathway Mast Cell Secretory Granule Organization Intracellular Transport Nucleocytoplasmic Transport Nuclear Transport Establishment Of Localization In Cell Endosome Transport Via Multivesicular Body Sorting Pathway Mature Ribosome Assembly Secretion Of Lysosomal Enzymes Negative Regulation Of Glycolytic Process Cellular Localization Ribosomal Subunit Export From Nucleus Radial Glial Cell Differentiation Phospholipid Homeostasis Response To Drug Interleukin-6-mediated Signaling Pathway Early Endosome To Late Endosome Transport Neutrophil Mediated Immunity JAK-STAT Cascade Involved In Growth Hormone Signaling Pathway Melanosome Organization Pigment Granule Organization Defense Response To Protozoan Growth Hormone Receptor Signaling Pathway Temperature Homeostasis Ribosomal Large Subunit Biogenesis Natural Killer Cell Mediated Cytotoxicity Positive Regulation Of Natural Killer Cell Activation Cellular Response To Growth Hormone Stimulus Cellular Response To Interleukin-6 Regulation Of Glycolytic Process Natural Killer Cell Mediated Immunity Positive Regulation Of Notch Signaling Pathway Response To Protozoan Ribosome Assembly Eating Behavior Negative Regulation Of Neuron Migration Chemical Homeostasis Response To Interleukin-6 T Cell Mediated Immunity Leukocyte Mediated Cytotoxicity Acute-phase Response Response To Growth Hormone Secretory Granule Organization Astrocyte Differentiation Anion Homeostasis Eye Photoreceptor Cell Differentiation JAK-STAT Cascade Regulation Of Neuron Migration Lysosome Organization
Tagcloud ?		40s 60s 80s associates biogenesis cerevisiae cessation depleted designated encodes imbalance lysates maps mer monosomes mr polyribosomes polysomal prevents ribosomal ribosomes saccharomyces stoichiometric subunits tif6 true ultimately xvi yeast
Tagcloud (Difference) ?		40s 60s 80s associates biogenesis cerevisiae cessation depleted designated encodes imbalance lysates maps mer monosomes mr polyribosomes polysomal prevents ribosomal ribosomes saccharomyces stoichiometric subunits tif6 true ultimately xvi yeast
Tagcloud (Intersection) ?