IGF2R and AGA

Number of citations of the paper that reports this interaction (PMID 9362483)
7

Data Source:
HPRD (in vitro)

		IGF2R	AGA
Gene Name		insulin-like growth factor 2 receptor	aspartylglucosaminidase
Image
Gene Ontology Annotations	Cellular Component	Extracellular Space Nuclear Envelope Lumen Lysosomal Membrane Endosome Late Endosome Trans-Golgi Network Integral Component Of Plasma Membrane Focal Adhesion Cell Surface Membrane Clathrin Coat Endocytic Vesicle Trans-Golgi Network Transport Vesicle Perinuclear Region Of Cytoplasm Extracellular Vesicular Exosome	Lysosome Endoplasmic Reticulum Extracellular Vesicular Exosome
	Molecular Function	Glycoprotein Binding G-protein Alpha-subunit Binding Retinoic Acid Binding Receptor Activity G-protein Coupled Receptor Activity Insulin-like Growth Factor-activated Receptor Activity Transporter Activity Protein Binding Mannose Binding Enzyme Binding Insulin-like Growth Factor II Binding Identical Protein Binding Phosphoprotein Binding	N4-(beta-N-acetylglucosaminyl)-L-asparaginase Activity Peptidase Activity Protein Self-association
	Biological Process	Liver Development Receptor-mediated Endocytosis Signal Transduction G-protein Coupled Receptor Signaling Pathway Spermatogenesis Post-embryonic Development Organ Regeneration Response To Retinoic Acid Positive Regulation Of Apoptotic Process Insulin-like Growth Factor Receptor Signaling Pathway	Proteolysis Protein Deglycosylation Protein Maturation
Pathways		Golgi Associated Vesicle Biogenesis trans-Golgi Network Vesicle Budding Clathrin derived vesicle budding
Drugs
Diseases
GWAS		Brain lesion load ( 19010793)	Serum selenium levels ( 23698163)
Protein-Protein Interactions		14 interactors: AGA ATXN1 CREG1 CSNK2A1 CTSD GGA1 GGA2 GGA3 GZMB IGF2 PACS1 PLAU PLAUR PLIN3	2 interactors: ALB IGF2R
Entrez ID		3482	175
HPRD ID		00928	01949
Ensembl ID		ENSG00000197081	ENSG00000038002
Uniprot IDs		P11717	P20933
PDB IDs		1E6F 1GP0 1GP3 1GQB 1JPL 1JWG 1LF8 2CNJ 2L29 2L2A 2V5N 2V5O 2V5P	1APY 1APZ
Enriched GO Terms of Interacting Partners?		Vesicle-mediated Transport Fibrinolysis Positive Regulation Of Protein Catabolic Process Negative Regulation Of Blood Coagulation Establishment Of Localization In Cell Negative Regulation Of Coagulation Urokinase Plasminogen Activator Signaling Pathway Negative Regulation Of Wound Healing Intracellular Transport Regulation Of Protein Catabolic Process Intracellular Protein Transport Cellular Localization Regulation Of Blood Coagulation Blood Coagulation Regulation Of Smooth Muscle Cell-matrix Adhesion Hemostasis Regulation Of Receptor Activity Protein Deglycosylation Insulin Receptor Signaling Pathway Via Phosphatidylinositol 3-kinase Regulation Of Mitotic Nuclear Division Regulation Of Wound Healing Positive Regulation Of Glycogen (starch) Synthase Activity Granzyme-mediated Apoptotic Signaling Pathway	Maintenance Of Mitochondrion Location Receptor-mediated Endocytosis Response To Platinum Ion Hemolysis By Symbiont Of Host Erythrocytes Positive Regulation Of Circadian Sleep/wake Cycle, Non-REM Sleep Regulation Of Circadian Sleep/wake Cycle, Non-REM Sleep Endocytosis Sodium-independent Organic Anion Transport Regulation Of Circadian Sleep/wake Cycle, Sleep Establishment Of Epithelial Cell Polarity Positive Regulation Of Circadian Rhythm Insulin-like Growth Factor Receptor Signaling Pathway Killing Of Cells Of Other Organism Cytolysis Response To Mercury Ion Bile Acid And Bile Salt Transport Mitochondrion Localization Bile Acid Metabolic Process Vesicle-mediated Transport Regulation Of Apoptotic Process Regulation Of Cell Death Retina Homeostasis Platelet Degranulation Apical Junction Assembly Organ Regeneration Regulation Of Circadian Rhythm Interaction With Host Establishment Of Cell Polarity Cell-cell Junction Assembly Response To Retinoic Acid Positive Regulation Of Behavior Monocarboxylic Acid Transport Response To Organic Substance Cellular Response To Starvation Post-embryonic Development Maintenance Of Location In Cell Liver Development Lipoprotein Metabolic Process Cilium Assembly Cellular Response To Nutrient Levels Response To Starvation Tissue Homeostasis Establishment Or Maintenance Of Cell Polarity Regulation Of Behavior Platelet Activation Cilium Organization Cell Junction Assembly Cell-cell Junction Organization Cellular Response To Extracellular Stimulus Response To Nutrient
Tagcloud ?		acting base box constitutes copies differentially discrimination distinguish dmr dmrs embryo encodes erased establishment germ gonads imprint imprinted imprinting includes maintained mark methylated methylation novo pair parent paternal phenomenon	agu aspartylglucosaminidase aspartylglucosaminuria beyond capability cation distributed endocytosed endocytosis endocytotic feasible hydrolase inactive lysosomal m6p m6prs mannose n18 neuroblastoma pc12 pheochromocytoma punctate soma steps storage tagged telencephalic terminals uptake
Tagcloud (Difference) ?		acting base box constitutes copies differentially discrimination distinguish dmr dmrs embryo encodes erased establishment germ gonads imprint imprinted imprinting includes maintained mark methylated methylation novo pair parent paternal phenomenon	agu aspartylglucosaminidase aspartylglucosaminuria beyond capability cation distributed endocytosed endocytosis endocytotic feasible hydrolase inactive lysosomal m6p m6prs mannose n18 neuroblastoma pc12 pheochromocytoma punctate soma steps storage tagged telencephalic terminals uptake
Tagcloud (Intersection) ?