AGA and IGF2R

Number of citations of the paper that reports this interaction (PMID 9362483)
7

Data Source:
HPRD (in vitro)

		AGA	IGF2R
Gene Name		aspartylglucosaminidase	insulin-like growth factor 2 receptor
Image
Gene Ontology Annotations	Cellular Component	Lysosome Endoplasmic Reticulum Extracellular Vesicular Exosome	Extracellular Space Nuclear Envelope Lumen Lysosomal Membrane Endosome Late Endosome Trans-Golgi Network Integral Component Of Plasma Membrane Focal Adhesion Cell Surface Membrane Clathrin Coat Endocytic Vesicle Trans-Golgi Network Transport Vesicle Perinuclear Region Of Cytoplasm Extracellular Vesicular Exosome
	Molecular Function	N4-(beta-N-acetylglucosaminyl)-L-asparaginase Activity Peptidase Activity Protein Self-association	Glycoprotein Binding G-protein Alpha-subunit Binding Retinoic Acid Binding Receptor Activity G-protein Coupled Receptor Activity Insulin-like Growth Factor-activated Receptor Activity Transporter Activity Protein Binding Mannose Binding Enzyme Binding Insulin-like Growth Factor II Binding Identical Protein Binding Phosphoprotein Binding
	Biological Process	Proteolysis Protein Deglycosylation Protein Maturation	Liver Development Receptor-mediated Endocytosis Signal Transduction G-protein Coupled Receptor Signaling Pathway Spermatogenesis Post-embryonic Development Organ Regeneration Response To Retinoic Acid Positive Regulation Of Apoptotic Process Insulin-like Growth Factor Receptor Signaling Pathway
Pathways			Golgi Associated Vesicle Biogenesis trans-Golgi Network Vesicle Budding Clathrin derived vesicle budding
Drugs
Diseases
GWAS		Serum selenium levels ( 23698163)	Brain lesion load ( 19010793)
Protein-Protein Interactions		2 interactors: ALB IGF2R	14 interactors: AGA ATXN1 CREG1 CSNK2A1 CTSD GGA1 GGA2 GGA3 GZMB IGF2 PACS1 PLAU PLAUR PLIN3
Entrez ID		175	3482
HPRD ID		01949	00928
Ensembl ID		ENSG00000038002	ENSG00000197081
Uniprot IDs		P20933	P11717
PDB IDs		1APY 1APZ	1E6F 1GP0 1GP3 1GQB 1JPL 1JWG 1LF8 2CNJ 2L29 2L2A 2V5N 2V5O 2V5P
Enriched GO Terms of Interacting Partners?		Maintenance Of Mitochondrion Location Receptor-mediated Endocytosis Response To Platinum Ion Hemolysis By Symbiont Of Host Erythrocytes Positive Regulation Of Circadian Sleep/wake Cycle, Non-REM Sleep Regulation Of Circadian Sleep/wake Cycle, Non-REM Sleep Endocytosis Sodium-independent Organic Anion Transport Regulation Of Circadian Sleep/wake Cycle, Sleep Establishment Of Epithelial Cell Polarity Positive Regulation Of Circadian Rhythm Insulin-like Growth Factor Receptor Signaling Pathway Killing Of Cells Of Other Organism Cytolysis Response To Mercury Ion Bile Acid And Bile Salt Transport Mitochondrion Localization Bile Acid Metabolic Process Vesicle-mediated Transport Regulation Of Apoptotic Process Regulation Of Cell Death Retina Homeostasis Platelet Degranulation Apical Junction Assembly Organ Regeneration Regulation Of Circadian Rhythm Interaction With Host Establishment Of Cell Polarity Cell-cell Junction Assembly Response To Retinoic Acid Positive Regulation Of Behavior Monocarboxylic Acid Transport Response To Organic Substance Cellular Response To Starvation Post-embryonic Development Maintenance Of Location In Cell Liver Development Lipoprotein Metabolic Process Cilium Assembly Cellular Response To Nutrient Levels Response To Starvation Tissue Homeostasis Establishment Or Maintenance Of Cell Polarity Regulation Of Behavior Platelet Activation Cilium Organization Cell Junction Assembly Cell-cell Junction Organization Cellular Response To Extracellular Stimulus Response To Nutrient	Vesicle-mediated Transport Fibrinolysis Positive Regulation Of Protein Catabolic Process Negative Regulation Of Blood Coagulation Establishment Of Localization In Cell Negative Regulation Of Coagulation Urokinase Plasminogen Activator Signaling Pathway Negative Regulation Of Wound Healing Intracellular Transport Regulation Of Protein Catabolic Process Intracellular Protein Transport Cellular Localization Regulation Of Blood Coagulation Blood Coagulation Regulation Of Smooth Muscle Cell-matrix Adhesion Hemostasis Regulation Of Receptor Activity Protein Deglycosylation Insulin Receptor Signaling Pathway Via Phosphatidylinositol 3-kinase Regulation Of Mitotic Nuclear Division Regulation Of Wound Healing Positive Regulation Of Glycogen (starch) Synthase Activity Granzyme-mediated Apoptotic Signaling Pathway
Tagcloud ?		agu aspartylglucosaminidase aspartylglucosaminuria beyond capability cation distributed endocytosed endocytosis endocytotic feasible hydrolase inactive lysosomal m6p m6prs mannose n18 neuroblastoma pc12 pheochromocytoma punctate soma steps storage tagged telencephalic terminals uptake	acting base box constitutes copies differentially discrimination distinguish dmr dmrs embryo encodes erased establishment germ gonads imprint imprinted imprinting includes maintained mark methylated methylation novo pair parent paternal phenomenon
Tagcloud (Difference) ?		agu aspartylglucosaminidase aspartylglucosaminuria beyond capability cation distributed endocytosed endocytosis endocytotic feasible hydrolase inactive lysosomal m6p m6prs mannose n18 neuroblastoma pc12 pheochromocytoma punctate soma steps storage tagged telencephalic terminals uptake	acting base box constitutes copies differentially discrimination distinguish dmr dmrs embryo encodes erased establishment germ gonads imprint imprinted imprinting includes maintained mark methylated methylation novo pair parent paternal phenomenon
Tagcloud (Intersection) ?