AGFG1 and VAMP7

Number of citations of the paper that reports this interaction (PMID 18775314)
37

Data Source:
HPRD (two hybrid, in vitro, in vivo)

		AGFG1	VAMP7
Gene Name		ArfGAP with FG repeats 1	vesicle-associated membrane protein 7
Image
Gene Ontology Annotations	Cellular Component	Nuclear Pore Cytoplasmic Membrane-bounded Vesicle Cell Projection Neuronal Cell Body Intracellular Membrane-bounded Organelle	Cytoplasm Lysosomal Membrane Endoplasmic Reticulum Membrane Golgi Apparatus Trans-Golgi Network Plasma Membrane Cell Surface Membrane Integral Component Of Membrane Lamellipodium Cell Junction Secretory Granule Transport Vesicle Membrane Secretory Granule Membrane Phagocytic Vesicle Membrane Platelet Alpha Granule Pseudopodium SNARE Complex Late Endosome Membrane Azurophil Granule Membrane Neuron Projection Intracellular Membrane-bounded Organelle Apical Part Of Cell Synapse Phagocytic Vesicle Perinuclear Region Of Cytoplasm Extracellular Vesicular Exosome
	Molecular Function	DNA Binding RNA Binding Protein Binding ARF GTPase Activator Activity Zinc Ion Binding	SNARE Binding SNAP Receptor Activity Protein Binding Syntaxin Binding
	Biological Process	Acrosome Assembly MRNA Export From Nucleus Multicellular Organismal Development Spermatid Nucleus Differentiation Regulation Of ARF GTPase Activity Positive Regulation Of GTPase Activity Intermediate Filament Organization	Autophagic Vacuole Fusion Exocytosis ER To Golgi Vesicle-mediated Transport Post-Golgi Vesicle-mediated Transport Endocytosis Vesicle Fusion Phagocytosis, Engulfment Endosome To Lysosome Transport Vesicle-mediated Transport Calcium Ion-dependent Exocytosis Triglyceride Transport SNARE Complex Assembly Golgi To Plasma Membrane Protein Transport Eosinophil Degranulation Neutrophil Degranulation Natural Killer Cell Degranulation Vesicle Fusion With Golgi Apparatus Membrane Organization Regulation Of Protein Targeting To Vacuolar Membrane Positive Regulation Of Histamine Secretion By Mast Cell
Pathways			Golgi Associated Vesicle Biogenesis trans-Golgi Network Vesicle Budding Clathrin derived vesicle budding Lysosome Vesicle Biogenesis
Drugs
Diseases
GWAS
Protein-Protein Interactions		11 interactors: APC APP EPS15 EPS15L1 ITSN1 NYAP2 PKIA POLE2 RNF216 VAMP7 XPO1	11 interactors: AGFG1 ANKRD27 AP3D1 DNAJC5 SNAP23 SNAP25 SNAP29 STX1A STX3 STX4 STX7
Entrez ID		3267	6845
HPRD ID		02918	02084
Ensembl ID		ENSG00000173744	ENSG00000124333
Uniprot IDs		P52594	P51809
PDB IDs		2D9L 2OLM 2VX8	2DMW
Enriched GO Terms of Interacting Partners?		Regulation Of Epidermal Growth Factor Receptor Signaling Pathway Regulation Of ERBB Signaling Pathway Endocytosis Regulation Of Cell Cycle Process Regulation Of Mitotic Cell Cycle Phase Transition Regulation Of Signaling Regulation Of Cell Cycle Phase Transition Neuron Projection Morphogenesis Regulation Of Intracellular Protein Transport Regulation Of G2/M Transition Of Mitotic Cell Cycle Negative Regulation Of Epidermal Growth Factor Receptor Signaling Pathway Regulation Of Cell Cycle G2/M Phase Transition Negative Regulation Of ERBB Signaling Pathway Vesicle-mediated Transport Regulation Of Protein Localization Neuron Projection Development Cell Projection Morphogenesis Cell Part Morphogenesis Regulation Of Protein Targeting To Vacuolar Membrane Enzyme Linked Receptor Protein Signaling Pathway Regulation Of Cell Cycle Regulation Of Signal Transduction Neuron Development Apoptotic Process Post-Golgi Vesicle-mediated Transport Regulation Of Mitotic Cell Cycle Programmed Cell Death Regulation Of Intracellular Transport Regulation Of Cellular Localization Synaptic Growth At Neuromuscular Junction Canonical Wnt Signaling Pathway Involved In Positive Regulation Of Apoptotic Process Cell Death Death Cell Morphogenesis Negative Regulation Of Signal Transduction Establishment Of Localization In Cell Neuron Differentiation Cell Surface Receptor Signaling Pathway Cell Projection Organization Ribosomal Small Subunit Export From Nucleus Positive Regulation Of Histamine Secretion By Mast Cell Regulation Of Histamine Secretion By Mast Cell Eosinophil Degranulation Collateral Sprouting In Absence Of Injury Triglyceride Transport Negative Regulation Of Signaling Axonogenesis Regulation Of Microtubule Cytoskeleton Organization Response To Stimulus Negative Regulation Of Protein Serine/threonine Kinase Activity	Synaptic Vesicle Fusion To Presynaptic Membrane Vesicle Organization Synaptic Vesicle Transport Vesicle Fusion Synaptic Vesicle Exocytosis Organelle Fusion Establishment Of Vesicle Localization Vesicle Localization Organelle Localization Neurotransmitter Secretion Membrane Fusion Regulation Of Neurotransmitter Levels Establishment Of Organelle Localization Neurotransmitter Transport Establishment Of Localization In Cell Vesicle-mediated Transport Cellular Localization Synaptic Transmission Exocytosis Vesicle Docking Membrane Docking Membrane Organization Secretion By Cell Cell-cell Signaling Secretion Synaptic Vesicle Priming Transport Intracellular Transport Positive Regulation Of Synaptic Transmission Organelle Organization Protein Transport Establishment Of Protein Localization Long-term Synaptic Potentiation Regulation Of Protein Localization To Plasma Membrane Positive Regulation Of Protein Localization To Cell Surface Protein Localization Synaptic Vesicle Docking Regulation Of Synaptic Transmission Cellular Protein Complex Assembly Regulation Of Protein Localization Intracellular Protein Transport Regulation Of Protein Localization To Cell Surface Regulation Of Synaptic Plasticity Glutamate Secretion Regulation Of Cellular Localization Positive Regulation Of Protein Localization To Plasma Membrane Cellular Component Assembly Regulation Of Cellular Component Organization Regulation Of Insulin Secretion Regulation Of Peptide Hormone Secretion
Tagcloud ?			acidification alters autophagosome compartments correlative docking fourth hallmark hijacking inside intravesicular lc3 localizes multimembrane nonacidic pave pseudotuberculosis replicate replicates traffic ultrastructurally unexpectedly uninfected vacuoles vamp3 vamps vesicle ycvs yersinia
Tagcloud (Difference) ?			acidification alters autophagosome compartments correlative docking fourth hallmark hijacking inside intravesicular lc3 localizes multimembrane nonacidic pave pseudotuberculosis replicate replicates traffic ultrastructurally unexpectedly uninfected vacuoles vamp3 vamps vesicle ycvs yersinia
Tagcloud (Intersection) ?