RHOD and PLXNA1

Number of citations of the paper that reports this interaction (PMID 11784792)
30

Data Source:
BioGRID (pull down)
HPRD (in vitro)

		RHOD	PLXNA1
Gene Name		ras homolog family member D	plexin A1
Image			No pdb structure
Gene Ontology Annotations	Cellular Component	Early Endosome Cytosol Plasma Membrane	Semaphorin Receptor Complex Nucleus Cytoplasm Plasma Membrane Integral Component Of Membrane Extracellular Vesicular Exosome
	Molecular Function	GTPase Activity GTP Binding Protein Kinase Binding	Receptor Activity Semaphorin Receptor Activity
	Biological Process	Protein Targeting Small GTPase Mediated Signal Transduction Rho Protein Signal Transduction Metabolic Process Lamellipodium Assembly Positive Regulation Of Cell Migration Positive Regulation Of Cell Adhesion Focal Adhesion Assembly Actin Filament Bundle Assembly Regulation Of Small GTPase Mediated Signal Transduction Regulation Of Focal Adhesion Assembly Regulation Of Actin Cytoskeleton Reorganization	Multicellular Organismal Development Axon Guidance Regulation Of Smooth Muscle Cell Migration Dichotomous Subdivision Of Terminal Units Involved In Salivary Gland Branching Semaphorin-plexin Signaling Pathway
Pathways		Rho GTPase cycle Signaling by Rho GTPases	Axon guidance Semaphorin interactions Other semaphorin interactions Sema3A PAK dependent Axon repulsion SEMA3A-Plexin repulsion signaling by inhibiting Integrin adhesion CRMPs in Sema3A signaling
Drugs
Diseases
GWAS		Height ( 20881960)	MRI atrophy measures ( 21116278)
Protein-Protein Interactions		14 interactors: ACVR1 ADCK5 ADRB2 ANKFY1 ARHGAP29 BMPR1B DIAPH2 HRAS IHH PLXNA1 SMAD2 SMAD4 SMURF2 TGFBR1	7 interactors: AKT1 FES NRP1 PLXNB1 RHOD RND1 SEMA6D
Entrez ID		29984	5361
HPRD ID		05776	11868
Ensembl ID		ENSG00000173156	ENSG00000114554
Uniprot IDs		E9PIG5 O00212	Q9UIW2
PDB IDs		2J1L
Enriched GO Terms of Interacting Partners?		Transmembrane Receptor Protein Serine/threonine Kinase Signaling Pathway Positive Regulation Of Signal Transduction Enzyme Linked Receptor Protein Signaling Pathway Transforming Growth Factor Beta Receptor Signaling Pathway Organ Morphogenesis Cellular Response To Transforming Growth Factor Beta Stimulus Response To Transforming Growth Factor Beta BMP Signaling Pathway Cell Development Pattern Specification Process Morphogenesis Of A Branching Epithelium Morphogenesis Of A Branching Structure Regulation Of Signal Transduction Regulation Of Transforming Growth Factor Beta Receptor Signaling Pathway Negative Regulation Of Transmembrane Receptor Protein Serine/threonine Kinase Signaling Pathway Cell Fate Commitment Activin Receptor Signaling Pathway Cellular Response To Growth Factor Stimulus Response To Growth Factor Regulation Of Signaling Cell Surface Receptor Signaling Pathway Tissue Morphogenesis Negative Regulation Of Cell Proliferation Tissue Development Positive Regulation Of Pathway-restricted SMAD Protein Phosphorylation Positive Regulation Of Bone Mineralization Cell Morphogenesis Involved In Differentiation Positive Regulation Of Biomineral Tissue Development Cell Differentiation Regulation Of Transcription From RNA Polymerase II Promoter Regulation Of Epithelial To Mesenchymal Transition Tube Morphogenesis Regulation Of Pathway-restricted SMAD Protein Phosphorylation Regulation Of Cellular Response To Growth Factor Stimulus Positive Regulation Of Transcription, DNA-templated Mesenchyme Development Endocardial Cell Differentiation Branching Morphogenesis Of An Epithelial Tube Heart Morphogenesis In Utero Embryonic Development Morphogenesis Of An Epithelium Heart Development Endothelial Cell Activation Positive Regulation Of Macromolecule Biosynthetic Process Negative Regulation Of Transforming Growth Factor Beta Receptor Signaling Pathway Stem Cell Development Regulation Of Bone Mineralization Positive Regulation Of Gene Expression Signal Transduction Germ Cell Development	Cell Projection Organization Axon Guidance Axonogenesis Axon Development Cell Morphogenesis Involved In Neuron Differentiation Chemotaxis Regulation Of Cell Adhesion Regulation Of Cell Motility Neuron Projection Morphogenesis Regulation Of Locomotion Regulation Of Cellular Component Movement Cell Morphogenesis Involved In Differentiation Generation Of Neurons Neurogenesis Neuron Projection Development Cell Projection Morphogenesis Positive Regulation Of Cell Migration Cell Part Morphogenesis Positive Regulation Of Cell Motility Cell Development Response To External Stimulus Positive Regulation Of Cellular Component Movement Positive Regulation Of Locomotion Neuron Development Regulation Of Neuron Projection Development Cell Morphogenesis Negative Regulation Of Osteoblast Proliferation Neuron Differentiation Nervous System Development Regulation Of Cell Projection Organization Locomotion Regulation Of Neuron Differentiation Regulation Of Cell Migration Movement Of Cell Or Subcellular Component Positive Regulation Of Smooth Muscle Cell Migration Regulation Of Osteoblast Proliferation Regulation Of Neurogenesis Positive Regulation Of Neuron Projection Development Semaphorin-plexin Signaling Pathway Regulation Of Cell Development Positive Regulation Of Cell Differentiation Positive Regulation Of Cell Projection Organization Cell Differentiation Regulation Of Actin Cytoskeleton Reorganization Regulation Of Smooth Muscle Cell Migration Regulation Of Cellular Component Organization Regulation Of Organelle Organization Positive Regulation Of Neuron Differentiation Positive Regulation Of Endothelial Cell Migration Positive Regulation Of Endothelial Cell Proliferation
Tagcloud ?		10nm 130nm 400nm 500ms 50nm 5x100hz bapta brevis buffering carbonylcyanide ctrl digitorum electrically electroporation fccp fdb flexor fluo footpads mag mfn2 mitofusin myoplasmic sarcomere tetani tetanic tethers transients trifluoromethoxyphenylhydrazone
Tagcloud (Difference) ?		10nm 130nm 400nm 500ms 50nm 5x100hz bapta brevis buffering carbonylcyanide ctrl digitorum electrically electroporation fccp fdb flexor fluo footpads mag mfn2 mitofusin myoplasmic sarcomere tetani tetanic tethers transients trifluoromethoxyphenylhydrazone
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