GSTA2 and GSTA4

Number of citations of the paper that reports this interaction (PMID 25416956)
0

Data Source:
BioGRID (two hybrid)

		GSTA2	GSTA4
Gene Name		glutathione S-transferase alpha 2	glutathione S-transferase alpha 4
Image
Gene Ontology Annotations	Cellular Component	Cytosol Extracellular Vesicular Exosome	Cytosol
	Molecular Function	Glutathione Transferase Activity	Glutathione Transferase Activity Protein Homodimerization Activity
	Biological Process	Glutathione Metabolic Process Xenobiotic Metabolic Process Epithelial Cell Differentiation Small Molecule Metabolic Process Glutathione Derivative Biosynthetic Process	Glutathione Metabolic Process Xenobiotic Metabolic Process Small Molecule Metabolic Process Glutathione Derivative Biosynthetic Process
Pathways		Defective OPLAH causes 5-oxoprolinase deficiency (OPLAHD) Defective AHCY causes Hypermethioninemia with S-adenosylhomocysteine hydrolase deficiency (HMAHCHD) Defective TPMT causes Thiopurine S-methyltransferase deficiency (TPMT deficiency) Defective MAT1A causes Methionine adenosyltransferase deficiency (MATD) Defective UGT1A4 causes hyperbilirubinemia Glutathione conjugation Metabolic disorders of biological oxidation enzymes Phase II conjugation Defective UGT1A1 causes hyperbilirubinemia Defective SLC35D1 causes Schneckenbecken dysplasia (SCHBCKD) Biological oxidations Defective GCLC causes Hemolytic anemia due to gamma-glutamylcysteine synthetase deficiency (HAGGSD) Defective GGT1 causes Glutathionuria (GLUTH) Defective GSS causes Glutathione synthetase deficiency (GSS deficiency)	Defective OPLAH causes 5-oxoprolinase deficiency (OPLAHD) Defective AHCY causes Hypermethioninemia with S-adenosylhomocysteine hydrolase deficiency (HMAHCHD) Defective TPMT causes Thiopurine S-methyltransferase deficiency (TPMT deficiency) Defective MAT1A causes Methionine adenosyltransferase deficiency (MATD) Defective UGT1A4 causes hyperbilirubinemia Glutathione conjugation Metabolic disorders of biological oxidation enzymes Phase II conjugation Defective UGT1A1 causes hyperbilirubinemia Defective SLC35D1 causes Schneckenbecken dysplasia (SCHBCKD) Biological oxidations Defective GCLC causes Hemolytic anemia due to gamma-glutamylcysteine synthetase deficiency (HAGGSD) Defective GGT1 causes Glutathionuria (GLUTH) Defective GSS causes Glutathione synthetase deficiency (GSS deficiency)
Drugs		Glutathione Chloroquine	Glutathione
Diseases
GWAS
Protein-Protein Interactions		2 interactors: GSTA1 GSTA4	2 interactors: C2orf50 GSTA2
Entrez ID		2939	2941
HPRD ID		00709	06899
Ensembl ID		ENSG00000244067	ENSG00000170899
Uniprot IDs		A8K987 P09210	O15217 Q6P4G1
PDB IDs		1AGS 2VCT 2WJU 4ACS	1GUL 1GUM 3IK7
Enriched GO Terms of Interacting Partners?		Glutathione Derivative Biosynthetic Process Glutathione Metabolic Process Xenobiotic Metabolic Process Cellular Response To Xenobiotic Stimulus Response To Xenobiotic Stimulus Peptide Metabolic Process Cellular Modified Amino Acid Metabolic Process Cellular Amide Metabolic Process Sulfur Compound Metabolic Process Small Molecule Metabolic Process	Glutathione Derivative Biosynthetic Process Glutathione Metabolic Process Xenobiotic Metabolic Process Cellular Response To Xenobiotic Stimulus Response To Xenobiotic Stimulus Peptide Metabolic Process Cellular Modified Amino Acid Metabolic Process Cellular Amide Metabolic Process Sulfur Compound Metabolic Process
Tagcloud ?		antigen appear approximate bp constitutive contain detoxification downregulates element fragment glutathione gsta1 gstalpha ikaros includes missing named prb promoters repress repression require resemble sufficient sv40 tagr transferase transient weights
Tagcloud (Difference) ?		antigen appear approximate bp constitutive contain detoxification downregulates element fragment glutathione gsta1 gstalpha ikaros includes missing named prb promoters repress repression require resemble sufficient sv40 tagr transferase transient weights
Tagcloud (Intersection) ?