MKNK2 and RPL7A

Number of citations of the paper that reports this interaction (PMID 20936779)
48

Data Source:
BioGRID (two hybrid)

		MKNK2	RPL7A
Gene Name		MAP kinase interacting serine/threonine kinase 2	ribosomal protein L7a
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Gene Ontology Annotations	Cellular Component	Nucleus Nucleoplasm Nucleolus Cytoplasm PML Body	Nucleus Cytosol Focal Adhesion Membrane Cytosolic Large Ribosomal Subunit Polysomal Ribosome Extracellular Vesicular Exosome
	Molecular Function	Protein Serine/threonine Kinase Activity Protein Binding ATP Binding Metal Ion Binding	RNA Binding Structural Constituent Of Ribosome Protein Binding Poly(A) RNA Binding
	Biological Process	Regulation Of Translation Protein Phosphorylation Cell Surface Receptor Signaling Pathway Hemopoiesis Intracellular Signal Transduction Cellular Response To Arsenic-containing Substance Extrinsic Apoptotic Signaling Pathway In Absence Of Ligand	Nuclear-transcribed MRNA Catabolic Process, Nonsense-mediated Decay Translation Translational Initiation Translational Elongation Translational Termination SRP-dependent Cotranslational Protein Targeting To Membrane Gene Expression Viral Process Viral Life Cycle Viral Transcription Ribosome Biogenesis Cellular Protein Metabolic Process
Pathways			Nonsense-Mediated Decay (NMD) Translation SRP-dependent cotranslational protein targeting to membrane Eukaryotic Translation Termination Peptide chain elongation Influenza Infection Viral mRNA Translation L13a-mediated translational silencing of Ceruloplasmin expression Influenza Life Cycle Nonsense Mediated Decay (NMD) enhanced by the Exon Junction Complex (EJC) Influenza Viral RNA Transcription and Replication GTP hydrolysis and joining of the 60S ribosomal subunit Eukaryotic Translation Initiation Formation of a pool of free 40S subunits Eukaryotic Translation Elongation Cap-dependent Translation Initiation Nonsense Mediated Decay (NMD) independent of the Exon Junction Complex (EJC)
Drugs
Diseases
GWAS
Protein-Protein Interactions		11 interactors: CUL2 EIF4E EIF4G1 ESR1 ESR2 MAPK1 MAPK14 MAPK8 RBX1 RPL7A VBP1	7 interactors: CCDC47 CTBP2 MKNK2 POLR2M SGOL1 SOCS3 STAU1
Entrez ID		2872	6130
HPRD ID		05459	01712
Ensembl ID		ENSG00000099875	ENSG00000148303
Uniprot IDs		B3KS07 Q9HBH9	P62424
PDB IDs		2AC3 2AC5 2HW7	3J3B
Enriched GO Terms of Interacting Partners?		Viral Process Regulation Of Sequence-specific DNA Binding Transcription Factor Activity Cellular Response To Lipid Toll-like Receptor 5 Signaling Pathway Toll-like Receptor 10 Signaling Pathway Toll-like Receptor TLR6:TLR2 Signaling Pathway Toll-like Receptor TLR1:TLR2 Signaling Pathway Toll-like Receptor 2 Signaling Pathway Toll-like Receptor 9 Signaling Pathway TRIF-dependent Toll-like Receptor Signaling Pathway Cellular Response To Hormone Stimulus MyD88-independent Toll-like Receptor Signaling Pathway Toll-like Receptor 3 Signaling Pathway MyD88-dependent Toll-like Receptor Signaling Pathway Cellular Response To Organic Substance Toll-like Receptor 4 Signaling Pathway Transmembrane Receptor Protein Tyrosine Kinase Signaling Pathway Cellular Protein Metabolic Process Toll-like Receptor Signaling Pathway Vagina Development Uterus Development Stress-activated MAPK Cascade Peptidyl-serine Phosphorylation Stress-activated Protein Kinase Signaling Cascade Response To Lipid Cellular Macromolecule Catabolic Process Regulation Of Gene Expression Pattern Recognition Receptor Signaling Pathway Innate Immune Response-activating Signal Transduction Intracellular Estrogen Receptor Signaling Pathway Enzyme Linked Receptor Protein Signaling Pathway Response To Organic Substance Activation Of Innate Immune Response Response To Hormone Nuclear-transcribed MRNA Catabolic Process Posttranscriptional Regulation Of Gene Expression Insulin Receptor Signaling Pathway Female Genitalia Development Mammary Gland Epithelial Cell Proliferation Apoptotic Process Cellular Response To Lipopolysaccharide Signal Transduction MRNA Catabolic Process Cellular Response To Molecule Of Bacterial Origin Response To Peptide Programmed Cell Death Regulation Of Transcription From RNA Polymerase II Promoter In Response To Hypoxia Cell Death Nuclear-transcribed MRNA Poly(A) Tail Shortening Death	Maintenance Of ER Location Maintenance Of Location In Cell Positive Regulation By Virus Of Viral Protein Levels In Host Cell Endoplasmic Reticulum Localization Spongiotrophoblast Differentiation Positive Regulation Of Retinoic Acid Receptor Signaling Pathway Centriole-centriole Cohesion Positive Regulation Of Chromatin Binding
Tagcloud ?		2b 4g au characterised comprise dfd dfg differ eif4e export importin inserts integrating lacks map mknk1 mnk mnk1a mnk2a mnks mrnas polybasic possesses scaffold share subcellular symbols termini unusual	arranged birds caenorhabditis clustered clustering dilysine drosophila elegans evolutionary genomes homologs integral invertebrate juxtaposition lineages mammals melanogaster polymorphic requirement seryl surf surfeit synthetase tata tight tightest transcribed trna vertebrate
Tagcloud (Difference) ?		2b 4g au characterised comprise dfd dfg differ eif4e export importin inserts integrating lacks map mknk1 mnk mnk1a mnk2a mnks mrnas polybasic possesses scaffold share subcellular symbols termini unusual	arranged birds caenorhabditis clustered clustering dilysine drosophila elegans evolutionary genomes homologs integral invertebrate juxtaposition lineages mammals melanogaster polymorphic requirement seryl surf surfeit synthetase tata tight tightest transcribed trna vertebrate
Tagcloud (Intersection) ?