GRK6 and SNCA

  • Number of citations of the paper that reports this interaction (PMID 10852916)
  • 68
  • Data Source:
  • BioGRID (enzymatic study)
  • HPRD (in vitro)

GRK6

SNCA

Gene Name G protein-coupled receptor kinase 6 synuclein, alpha (non A4 component of amyloid precursor)
Image
Gene Ontology Annotations Cellular Component
Molecular Function
Biological Process
Pathways
Drugs
Diseases
GWAS
Protein-Protein Interactions 18 interactors: ADRB2 BDKRB2 CHRM3 EDNRA EDNRB FSHR GIT1 ITGA5 KCNIP3 LTB4R PRSS23 RCVRN RHO SLC9A3R1 SNCA SNCB SNCG TBXA2R 110 interactors: A1BG ACTA1 ADAP2 ADRBK1 AKT1 ANXA6 APLP1 APP ARHGAP15 ARPP19 BAD BAG5 BAX BCL2L1 BDH2 CALM1 CAV1 CDC42EP2 CDC42EP3 CDC42SE1 CDK4 COL25A1 COX1 COX3 CRYAB CSNK1A1 CSNK1D CSNK2A1 CSNK2A2 CTNND1 CYCS DMTN DOCK7 DYNC1H1 DYRK1A EEF1A1 EIF3G ELK1 ENC1 ENSA FGR FKBP4 FYN GABARAPL1 GAPDH GRK1 GRK5 GRK6 GSK3B HSD17B4 HSP90AA1 HSPA1A HSPA8 HSPB1 HSPB2 HSPB6 HSPB8 IARS KIAA1191 KLC1 KLK6 LYN MAP1B MAPK1 MAPK8IP1 MAPT MEF2D NEDD4 NEDD4L PAK3 PARK2 PDE4DIP PELP1 PFDN2 PINK1 PLCB2 PLD1 PLK1 PLK2 PLK3 PRDX1 PRKCE PTK2B RABAC1 RNF10 SAP30BP SDF4 SEPT4 SIAH1 SIAH2 SLC6A3 SNCAIP SNCB SPTBN1 SQSTM1 SRC SRI SUMO2 SYK SYN1 TGM1 TH TOR1A TUBA1A UBB UBC USP47 YWHAB YWHAE YWHAH
Entrez ID 2870 6622
HPRD ID 02925 01227
Ensembl ID ENSG00000198055 ENSG00000145335
Uniprot IDs P43250 H6UYS0 H6UYS5 P37840
PDB IDs 2ACX 3NYN 3NYO 1XQ8 2JN5 2KKW 2M55 2X6M 3Q25 3Q26 3Q27 3Q28 3Q29
Enriched GO Terms of Interacting Partners?
Tagcloud ?
apparent  appear  autoinhibitory  autophosphorylated  autophosphorylation  ca2  calmodulin  conservation  contributes  coupled  define  deletion  domain  evolutionary  example  functionally  grk4  grk5  grks  localization  nonreceptor  palmitoylated  phospholipid  phospholipids  phosphorylated  residues  subject  substrates  translational 
2de  angustifolia  apoa1  atp5a1  atp5a1were  bioinformatics  caliber  david  diminishing  dysregulated  histopathology  hspa5  kegg  la  lavandula  lavender  le  likewise  ontology  operate  pharmaceutically  prdx2  predictedinteractions  scrutinized  searching  slowing  string  sum  tof 
Tagcloud (Difference) ?
apparent  appear  autoinhibitory  autophosphorylated  autophosphorylation  ca2  calmodulin  conservation  contributes  coupled  define  deletion  domain  evolutionary  example  functionally  grk4  grk5  grks  localization  nonreceptor  palmitoylated  phospholipid  phospholipids  phosphorylated  residues  subject  substrates  translational 
2de  angustifolia  apoa1  atp5a1  atp5a1were  bioinformatics  caliber  david  diminishing  dysregulated  histopathology  hspa5  kegg  la  lavandula  lavender  le  likewise  ontology  operate  pharmaceutically  prdx2  predictedinteractions  scrutinized  searching  slowing  string  sum  tof 
Tagcloud (Intersection) ?