ANK1 and RHAG

Number of citations of the paper that reports this interaction (PMID 12719424)
16

Data Source:
BioGRID (pull down)
HPRD (in vitro, two hybrid)

		ANK1	RHAG
Gene Name		ankyrin 1, erythrocytic	Rh-associated glycoprotein
Image			No pdb structure
Gene Ontology Annotations	Cellular Component	Nucleus Cytosol Cytoskeleton Plasma Membrane Spectrin-associated Cytoskeleton Basolateral Plasma Membrane Sarcoplasmic Reticulum Z Disc Axolemma Cortical Cytoskeleton M Band Sarcolemma Postsynaptic Membrane	Plasma Membrane Integral Component Of Plasma Membrane
	Molecular Function	Structural Molecule Activity Structural Constituent Of Cytoskeleton Protein Binding Cytoskeletal Adaptor Activity Enzyme Binding Spectrin Binding ATPase Binding	Ammonium Transmembrane Transporter Activity Ankyrin Binding
	Biological Process	Porphyrin-containing Compound Biosynthetic Process Exocytosis ER To Golgi Vesicle-mediated Transport Cytoskeleton Organization Signal Transduction Axon Guidance Positive Regulation Of Organelle Organization Monovalent Inorganic Cation Transport Maintenance Of Epithelial Cell Apical/basal Polarity Erythrocyte Development Iron Ion Homeostasis Protein Targeting To Plasma Membrane	Cellular Ion Homeostasis Carbon Dioxide Transport Ammonium Transport Bicarbonate Transport Small Molecule Metabolic Process Erythrocyte Development Transmembrane Transport Multicellular Organismal Iron Ion Homeostasis Ammonium Transmembrane Transport
Pathways		Interaction between L1 and Ankyrins CHL1 interactions Axon guidance Neurofascin interactions NrCAM interactions L1CAM interactions	O2/CO2 exchange in erythrocytes Erythrocytes take up carbon dioxide and release oxygen Rhesus glycoproteins mediate ammonium transport. Transport of glucose and other sugars, bile salts and organic acids, metal ions and amine compounds Erythrocytes take up oxygen and release carbon dioxide SLC-mediated transmembrane transport
Drugs
Diseases
GWAS		Glycated hemoglobin levels ( 20858683) Pulmonary function decline ( 22424883) Type 2 diabetes ( 22456796)
Protein-Protein Interactions		18 interactors: BLOC1S6 CD44 EPB42 ITPR3 KCTD6 L1CAM NBPF3 NEDD8 NFASC OBSCN RHAG SLC4A1 SLC4A3 SPTA1 SPTAN1 SPTB TIAM1 TTN	5 interactors: ANK1 CD47 GYPB ICAM4 SLC4A1
Entrez ID		286	6005
HPRD ID		01693	01582
Ensembl ID		ENSG00000029534	ENSG00000112077
Uniprot IDs		B3KX39 P16157	Q02094 Q96E98
PDB IDs		1N11 2YQF 2YVI 3F59 3KBT 3KBU 3UD1 3UD2
Enriched GO Terms of Interacting Partners?		Cell Development Anatomical Structure Morphogenesis Axon Guidance Movement Of Cell Or Subcellular Component Neuron Projection Development Locomotion Axonogenesis Anatomical Structure Development Bicarbonate Transport Axon Development Cellular Response To Growth Factor Stimulus Cell Morphogenesis Involved In Neuron Differentiation Neuron Development Chemotaxis Response To Growth Factor Cell Differentiation Neuron Projection Morphogenesis Cell Morphogenesis Developmental Process Neuron Differentiation Cell Morphogenesis Involved In Differentiation Actin Filament Capping Cell Projection Organization Blood Coagulation Multicellular Organismal Development Hemostasis Negative Regulation Of Actin Filament Depolymerization Response To External Stimulus Cell Projection Morphogenesis Regulation Of Actin Filament Depolymerization Cell Part Morphogenesis Chemical Homeostasis System Development Negative Regulation Of Actin Filament Polymerization Homeostatic Process Cellular Chemical Homeostasis Negative Regulation Of Protein Polymerization Ion Homeostasis Regulation Of Body Fluid Levels Negative Regulation Of Protein Complex Disassembly Wound Healing Generation Of Neurons Hemopoiesis Regulation Of Protein Depolymerization Nervous System Development Neurogenesis Regulation Of Protein Complex Disassembly Response To Wounding Cellular Homeostasis Immune System Development
Tagcloud ?		antiglobulin appointment bilirubin cared cytoskeletal cytoskeleton damaged delays discharged e508k epb41 epb42 erythrocyte incompatibility kernicterus neurologic newborn parent persisted phototherapy retesting return silico slc4a1 smear spherocytes spta1 sptb ugt1a1	ae ammonium anchoring ankyrin band basolateral bilayer biosynthesis challenge constitutes emerging erythroid gpc member membrane mutated next null observations p55 polarized red rhbg similarly skeleton spectrin summarize weak
Tagcloud (Difference) ?		antiglobulin appointment bilirubin cared cytoskeletal cytoskeleton damaged delays discharged e508k epb41 epb42 erythrocyte incompatibility kernicterus neurologic newborn parent persisted phototherapy retesting return silico slc4a1 smear spherocytes spta1 sptb ugt1a1	ae ammonium anchoring ankyrin band basolateral bilayer biosynthesis challenge constitutes emerging erythroid gpc member membrane mutated next null observations p55 polarized red rhbg similarly skeleton spectrin summarize weak
Tagcloud (Intersection) ?