RHAG and SLC4A1

Number of citations of the paper that reports this interaction (PMID 12531814)
63

Data Source:
HPRD (in vivo)

		RHAG	SLC4A1
Gene Name		Rh-associated glycoprotein	solute carrier family 4 (anion exchanger), member 1 (Diego blood group)
Image		No pdb structure
Gene Ontology Annotations	Cellular Component	Plasma Membrane Integral Component Of Plasma Membrane	Plasma Membrane Integral Component Of Plasma Membrane Integral Component Of Membrane Basolateral Plasma Membrane Z Disc Cortical Cytoskeleton Extracellular Vesicular Exosome Blood Microparticle
	Molecular Function	Ammonium Transmembrane Transporter Activity Ankyrin Binding	Actin Binding Inorganic Anion Exchanger Activity Protein Binding Protein C-terminus Binding Anion Transmembrane Transporter Activity Bicarbonate Transmembrane Transporter Activity Chloride Transmembrane Transporter Activity Anion:anion Antiporter Activity Ankyrin Binding Protein Homodimerization Activity Protein Anchor
	Biological Process	Cellular Ion Homeostasis Carbon Dioxide Transport Ammonium Transport Bicarbonate Transport Small Molecule Metabolic Process Erythrocyte Development Transmembrane Transport Multicellular Organismal Iron Ion Homeostasis Ammonium Transmembrane Transport	Ion Transport Anion Transport Chloride Transport Cellular Ion Homeostasis Bicarbonate Transport Small Molecule Metabolic Process Regulation Of Intracellular PH Transmembrane Transport Chloride Transmembrane Transport
Pathways		O2/CO2 exchange in erythrocytes Erythrocytes take up carbon dioxide and release oxygen Rhesus glycoproteins mediate ammonium transport. Transport of glucose and other sugars, bile salts and organic acids, metal ions and amine compounds Erythrocytes take up oxygen and release carbon dioxide SLC-mediated transmembrane transport	O2/CO2 exchange in erythrocytes Erythrocytes take up carbon dioxide and release oxygen Transport of inorganic cations/anions and amino acids/oligopeptides Erythrocytes take up oxygen and release carbon dioxide SLC-mediated transmembrane transport Bicarbonate transporters
Drugs
Diseases
GWAS			Obesity-related traits ( 23251661)
Protein-Protein Interactions		5 interactors: ANK1 CD47 GYPB ICAM4 SLC4A1	13 interactors: ACTC1 ANK1 BLOC1S6 CA2 CA4 CANX CDKN2A EPB41 EPB42 LYN RHAG SLC4A1AP SYK
Entrez ID		6005	6521
HPRD ID		01582	00175
Ensembl ID		ENSG00000112077	ENSG00000004939
Uniprot IDs		Q02094 Q96E98	P02730
PDB IDs			1BH7 1BNX 1BTQ 1BTR 1BTS 1BTT 1BZK 1HYN 2BTA 2BTB 3BTB
Enriched GO Terms of Interacting Partners?			Erythrocyte Differentiation Erythrocyte Homeostasis Secretion Bicarbonate Transport Myeloid Cell Homeostasis Developmental Process Erythrocyte Development Secretion By Cell Homeostasis Of Number Of Cells Myeloid Cell Differentiation Ammonium Transport Hemopoiesis Anion Transport Immune System Development Exocytosis Organ Development System Development Iron Ion Homeostasis Positive Regulation Of Bone Resorption Regulation Of Platelet Aggregation Protein Secretion Negative Regulation Of B Cell Proliferation Regulation Of Lymphocyte Activation Transition Metal Ion Homeostasis Multicellular Organismal Development Regulation Of Cell Activation Regulation Of Mast Cell Degranulation Anatomical Structure Development Production Of Molecular Mediator Involved In Inflammatory Response Regulation Of Platelet Activation Positive Regulation Of Tissue Remodeling Ion Transport Positive Regulation Of Leukocyte Apoptotic Process Cell Development Ion Homeostasis Regulation Of Mast Cell Activation Regulation Of Bone Resorption Negative Regulation Of B Cell Activation Regulation Of Regulated Secretory Pathway B Cell Receptor Signaling Pathway Peptidyl-tyrosine Autophosphorylation Regulation Of Cell Adhesion Mediated By Integrin One-carbon Metabolic Process Regulation Of Bone Remodeling Monovalent Inorganic Cation Transport Inorganic Anion Transport Regulation Of Immune System Process Immune System Process Homeostatic Process Regulation Of T Cell Activation
Tagcloud ?		ae ammonium anchoring ankyrin band basolateral bilayer biosynthesis challenge constitutes emerging erythroid gpc member membrane mutated next null observations p55 polarized red rhbg similarly skeleton spectrin summarize weak	acidosis ae1 anion bicarbonate calnexin cotranslationally destination exchanger folded folding glycoproteins glycosylated hereditary interfere kae1 misfolded monitors ovalocytosis properly retrotranslocation slc26 southeast spherocytosis summarizes traffic trafficking transporters ubiquitinylation
Tagcloud (Difference) ?		ae ammonium anchoring ankyrin band basolateral bilayer biosynthesis challenge constitutes emerging erythroid gpc member membrane mutated next null observations p55 polarized red rhbg similarly skeleton spectrin summarize weak	acidosis ae1 anion bicarbonate calnexin cotranslationally destination exchanger folded folding glycoproteins glycosylated hereditary interfere kae1 misfolded monitors ovalocytosis properly retrotranslocation slc26 southeast spherocytosis summarizes traffic trafficking transporters ubiquitinylation
Tagcloud (Intersection) ?