KLHL35 and APPBP2

Number of citations of the paper that reports this interaction (PMID 25416956)
0

Data Source:
BioGRID (two hybrid)

		KLHL35	APPBP2
Gene Name		kelch-like family member 35	amyloid beta precursor protein (cytoplasmic tail) binding protein 2
Image		No pdb structure	No pdb structure
Gene Ontology Annotations	Cellular Component		Nucleus Cytoplasm Microtubule Microtubule Associated Complex Cytoplasmic Vesicle Membrane
	Molecular Function		Microtubule Motor Activity Protein Binding
	Biological Process		Intracellular Protein Transport Metabolic Process Intracellular Transport
Pathways
Drugs
Diseases
GWAS
Protein-Protein Interactions		4 interactors: ACVR1 ALAS1 APPBP2 TGFBR1	79 interactors: AHCY AIM2 AK3 ANKRD10 APP AR ARMCX5 C1orf50 C6orf226 CALM3 CCDC85C CCNL1 CDK16 CHMP5 CLCN1 CNTFR COL24A1 CORO2B CREB3 CSNK1G2 CTC1 DCD DHRS2 DPEP1 EID3 EPT1 ERO1L FAM19A4 FAM92A1 FSTL1 FXYD7 GALNT3 GCSAM GP9 GSTP1 HIPK4 HIST1H2AK HSPA4 KIF6 KLF11 KLHL35 LANCL2 LONRF3 LUC7L2 LUZP4 MFSD3 MGC34796 MLLT3 MUL1 NFYA NPRL3 PCSK5 PI4KAP2 PPP1R8 PRKAA2 PRKACB PYROXD2 RASSF5 RNF128 RNF34 RRS1 SELV SLC22A6 SLC25A23 SNX5 ST8SIA5 SYNRG SYT11 TAF11 TBL3 TCF25 UBE2R2 UGGT2 WAS WDR24 WNT5B ZC3H10 ZCCHC12 ZNF747
Entrez ID		283212	10513
HPRD ID		08747	05616
Ensembl ID		ENSG00000149243	ENSG00000062725
Uniprot IDs		F5H412 Q6PF15	Q92624
PDB IDs
Enriched GO Terms of Interacting Partners?		Pathway-restricted SMAD Protein Phosphorylation Pharyngeal System Development Activin Receptor Signaling Pathway Positive Regulation Of Pathway-restricted SMAD Protein Phosphorylation Peptidyl-threonine Phosphorylation Regulation Of Pathway-restricted SMAD Protein Phosphorylation Negative Regulation Of Transmembrane Receptor Protein Serine/threonine Kinase Signaling Pathway Mesenchymal Cell Development Endocardial Cushion Cell Fate Commitment Negative Regulation Of Extrinsic Apoptotic Signaling Pathway Mesenchymal Cell Differentiation Transforming Growth Factor Beta Receptor Signaling Pathway Ameboidal-type Cell Migration Cellular Response To Transforming Growth Factor Beta Stimulus Response To Transforming Growth Factor Beta Regulation Of Extrinsic Apoptotic Signaling Pathway Mesenchyme Development Heart Morphogenesis Transmembrane Receptor Protein Serine/threonine Kinase Signaling Pathway Stem Cell Development Negative Regulation Of Apoptotic Signaling Pathway Signal Transduction By Phosphorylation Cell Fate Commitment Mitral Valve Morphogenesis Cardiac Muscle Cell Fate Commitment Stem Cell Differentiation Mitral Valve Development Embryonic Organ Morphogenesis Angiogenesis Positive Regulation Of Determination Of Dorsal Identity Parathyroid Gland Development Urogenital System Development Negative Regulation Of Activin Receptor Signaling Pathway Protoporphyrinogen IX Biosynthetic Process Atrial Septum Primum Morphogenesis Endocardial Cell Differentiation Septum Primum Development Blood Vessel Morphogenesis Endothelial Cell Activation Protoporphyrinogen IX Metabolic Process Pattern Specification Process Positive Regulation Of SMAD Protein Import Into Nucleus Embryonic Organ Development In Utero Embryonic Development Blood Vessel Development Heart Development Regulation Of SMAD Protein Import Into Nucleus Muscle Cell Fate Commitment Vasculature Development Germ Cell Migration	Regulation Of Defense Response To Virus By Host Response To Stress Nucleotide-binding Domain, Leucine Rich Repeat Containing Receptor Signaling Pathway Homocysteine Metabolic Process Cellular Response To Organic Substance
Tagcloud ?			10kb arhgap32 bcas3 breakpoints ccdc49 coamplification col14a1 coregulator ddx5 depdc6 deptor enpp2 hoxb9 lasp1 leukaemias nrip1 oprd1 painting pcgf2 phf20l1 plec1 skap1 taok1 tiam1 timm23 trps1 unamplified usp32 zmym4
Tagcloud (Difference) ?			10kb arhgap32 bcas3 breakpoints ccdc49 coamplification col14a1 coregulator ddx5 depdc6 deptor enpp2 hoxb9 lasp1 leukaemias nrip1 oprd1 painting pcgf2 phf20l1 plec1 skap1 taok1 tiam1 timm23 trps1 unamplified usp32 zmym4
Tagcloud (Intersection) ?