GP1BA and TPST1

Number of citations of the paper that reports this interaction (PMID 7721887)
15

Data Source:
HPRD (in vivo)

		GP1BA	TPST1
Gene Name		glycoprotein Ib (platelet), alpha polypeptide	tyrosylprotein sulfotransferase 1
Image		No pdb structure	No pdb structure
Gene Ontology Annotations	Cellular Component	Plasma Membrane Integral Component Of Plasma Membrane Cell Surface Membrane Anchored Component Of External Side Of Plasma Membrane Extracellular Vesicular Exosome	Golgi Membrane Membrane Integral Component Of Membrane
	Molecular Function	Protein Binding Thrombin Receptor Activity	Protein-tyrosine Sulfotransferase Activity
	Biological Process	Cell Morphogenesis Cell Adhesion Cell Surface Receptor Signaling Pathway Blood Coagulation Blood Coagulation, Intrinsic Pathway Platelet Activation Regulation Of Blood Coagulation Fibrinolysis Thrombin Receptor Signaling Pathway	Peptidyl-tyrosine Sulfation Inflammatory Response
Pathways
Drugs		Alpha-D-Mannose
Diseases
GWAS		Platelet counts ( 22139419 20139978)
Protein-Protein Interactions		16 interactors: CTSG DDIT3 F11 F12 F2 FLNA FLNB GP5 GP9 ITGAM KNG1 OSGEP SELP TPST1 VWF YWHAZ	6 interactors: CCR1 CCR8 CMKLR1 GP1BA GPR1 SELPLG
Entrez ID		2811	8460
HPRD ID		01976	07216
Ensembl ID		ENSG00000185245	ENSG00000169902
Uniprot IDs		E7ES66	O60507
PDB IDs
Enriched GO Terms of Interacting Partners?		Blood Coagulation, Intrinsic Pathway Blood Coagulation Hemostasis Regulation Of Body Fluid Levels Wound Healing Response To Wounding Platelet Activation Protein Activation Cascade Regulation Of Blood Coagulation Cell Activation Response To Stress Regulation Of Wound Healing Negative Regulation Of Blood Coagulation Negative Regulation Of Coagulation Negative Regulation Of Wound Healing Inflammatory Response Regulation Of Fibrinolysis Platelet Degranulation Defense Response Regulation Of Platelet Activation Positive Regulation Of Blood Coagulation Response To Stimulus Exocytosis Positive Regulation Of Fibrinolysis Positive Regulation Of Coagulation Positive Regulation Of Wound Healing Secretion By Cell MRNA Transcription From RNA Polymerase II Promoter MRNA Transcription Secretion Negative Regulation Of Platelet Activation Cell Adhesion Regulation Of Ion Homeostasis Cellular Extravasation Fibrinolysis Cytosolic Calcium Ion Homeostasis Leukocyte Migration Positive Regulation Of Intracellular Transport Protein Processing Cellular Localization Negative Regulation Of Determination Of Dorsal Identity Positive Regulation Of Phospholipase C-activating G-protein Coupled Receptor Signaling Pathway Protein Metabolic Process Positive Regulation Of Phosphatidylinositol 3-kinase Signaling Cellular Calcium Ion Homeostasis Calcium Ion Homeostasis Acute Inflammatory Response Positive Regulation Of Transport Establishment Of Localization In Cell Threonylcarbamoyladenosine Biosynthetic Process	Chemokine-mediated Signaling Pathway G-protein Coupled Receptor Signaling Pathway Cellular Response To Cytokine Stimulus Response To Cytokine Cell Adhesion Locomotion Positive Regulation Of Leukocyte Chemotaxis Cytokine-mediated Signaling Pathway Positive Regulation Of Leukocyte Migration Cell Surface Receptor Signaling Pathway Chemotaxis Positive Regulation Of Chemotaxis Regulation Of Leukocyte Migration Positive Regulation Of Behavior Response To Wounding Cellular Response To Stimulus Leukocyte Adhesive Activation Regulation Of Chemotaxis Cellular Response To Organic Substance G-protein Coupled Receptor Signaling Pathway, Coupled To Cyclic Nucleotide Second Messenger Positive Regulation Of Cytosolic Calcium Ion Concentration Cytosolic Calcium Ion Homeostasis Immune System Process Regulation Of Behavior Leukocyte Migration Response To Organic Substance Response To Stimulus Positive Regulation Of Macrophage Chemotaxis Cellular Calcium Ion Homeostasis Calcium Ion Homeostasis Signal Transduction Positive Regulation Of Monocyte Chemotaxis Positive Regulation Of Cell Migration Immune Response Positive Regulation Of Cell Motility Thrombin Receptor Signaling Pathway Positive Regulation Of Cellular Component Movement Positive Regulation Of Locomotion Leukocyte Tethering Or Rolling Regulation Of Macrophage Chemotaxis Regulation Of Monocyte Chemotaxis Dendritic Cell Chemotaxis Signaling Cell Communication Blood Coagulation, Intrinsic Pathway Cellular Metal Ion Homeostasis Blood Coagulation Hemostasis Cellular Cation Homeostasis Negative Regulation Of Interleukin-12 Production
Tagcloud ?		acantholysis anxa8l1 atp2c1 blistering c5a cd1b cd32 cd88 cdh8 cdh9 chrm3 chrnd chrne col21a1 cyb5b desmoglein dra dsc1 dsc3 justifies mucocutaneous multiplexed ndufs1 pdha1 pemphigus pkp3 pmp22 slc36a4 sod2
Tagcloud (Difference) ?		acantholysis anxa8l1 atp2c1 blistering c5a cd1b cd32 cd88 cdh8 cdh9 chrm3 chrnd chrne col21a1 cyb5b desmoglein dra dsc1 dsc3 justifies mucocutaneous multiplexed ndufs1 pdha1 pemphigus pkp3 pmp22 slc36a4 sod2
Tagcloud (Intersection) ?