RPS6KC1 and PRDX3

Number of citations of the paper that reports this interaction (PMID 21988832)
14

Data Source:
BioGRID (two hybrid)
HPRD (in vivo, in vitro, two hybrid)

		RPS6KC1	PRDX3
Gene Name		ribosomal protein S6 kinase, 52kDa, polypeptide 1	peroxiredoxin 3
Image		No pdb structure	No pdb structure
Gene Ontology Annotations	Cellular Component	Cytoplasm Early Endosome Membrane Intracellular Membrane-bounded Organelle	Cytoplasm Mitochondrion Mitochondrial Matrix Early Endosome Cytosol IkappaB Kinase Complex Extracellular Vesicular Exosome
	Molecular Function	Protein Serine/threonine Kinase Activity Protein Binding ATP Binding Phosphatidylinositol Binding	Protein Binding Protein C-terminus Binding Thioredoxin Peroxidase Activity Alkyl Hydroperoxide Reductase Activity Kinase Binding Protein Kinase Binding Identical Protein Binding Cysteine-type Endopeptidase Inhibitor Activity Involved In Apoptotic Process
	Biological Process	Protein Phosphorylation Signal Transduction	Response To Reactive Oxygen Species Maternal Placenta Development Response To Oxidative Stress Mitochondrion Organization Positive Regulation Of Cell Proliferation Peptidyl-cysteine Oxidation Myeloid Cell Differentiation Response To Lipopolysaccharide Negative Regulation Of Kinase Activity Cellular Response To Oxidative Stress Cellular Response To Reactive Oxygen Species Response To Hydrogen Peroxide Hydrogen Peroxide Catabolic Process Negative Regulation Of Apoptotic Process Negative Regulation Of Cysteine-type Endopeptidase Activity Involved In Apoptotic Process Positive Regulation Of NF-kappaB Transcription Factor Activity Regulation Of Mitochondrial Membrane Potential
Pathways			Detoxification of Reactive Oxygen Species
Drugs
Diseases
GWAS
Protein-Protein Interactions		3 interactors: PBX2 PRDX3 SPHK1	9 interactors: GORASP2 HNRNPD MAGEA11 MAP3K13 NEK6 PRDX4 RPS6KC1 SUMO4 TNFRSF1A
Entrez ID		26750	10935
HPRD ID		10204	05305
Ensembl ID		ENSG00000136643	ENSG00000165672
Uniprot IDs		F5H7T0 Q96S38	E9PH29 P30048
PDB IDs
Enriched GO Terms of Interacting Partners?		Cellular Response To Reactive Oxygen Species Positive Regulation Of NF-kappaB Transcription Factor Activity Response To Hydrogen Peroxide Sphingoid Catabolic Process Response To Reactive Oxygen Species Cellular Response To Oxidative Stress Peptidyl-cysteine Oxidation Positive Regulation Of Sequence-specific DNA Binding Transcription Factor Activity Female Pregnancy Regulation Of Sequence-specific DNA Binding Transcription Factor Activity Protein Oxidation Response To Oxidative Stress Response To Inorganic Substance Sphingosine Metabolic Process Positive Regulation Of Neurotransmitter Secretion Cyclooxygenase Pathway Regulation Of Tumor Necrosis Factor-mediated Signaling Pathway Response To Magnesium Ion Hydrogen Peroxide Catabolic Process Prostaglandin Biosynthetic Process Positive Regulation Of NF-kappaB Import Into Nucleus Response To ATP Positive Regulation Of Smooth Muscle Contraction Prostaglandin Metabolic Process Positive Regulation Of Cell Proliferation Sphingolipid Catabolic Process Response To Lipid Membrane Lipid Catabolic Process Regulation Of Mitochondrial Membrane Potential Hydrogen Peroxide Metabolic Process Negative Regulation Of Apoptotic Process Negative Regulation Of Programmed Cell Death Positive Regulation Of Transcription Factor Import Into Nucleus Negative Regulation Of Cell Death Regulation Of NF-kappaB Import Into Nucleus Maternal Placenta Development Icosanoid Biosynthetic Process Regulation Of Interleukin-1 Beta Production Proximal/distal Pattern Formation Regulation Of Transcription, DNA-templated Response To Amine Response To Progesterone Protein Kinase C-activating G-protein Coupled Receptor Signaling Pathway Regulation Of Nucleic Acid-templated Transcription Regulation Of RNA Biosynthetic Process Unsaturated Fatty Acid Biosynthetic Process Regulation Of Smooth Muscle Contraction Regulation Of RNA Metabolic Process 'de Novo' Posttranslational Protein Folding Cellular Response To Hydrogen Peroxide
Tagcloud ?		braf cure epha3 exons flt3 glioblastoma glioblastomas gliomagenesis hgg idh1 idh2 mapping mining mutated mutational nras offer opportunities pi3k pik3ca pten rational relapsing sequenced somatic synonymous tgfbr2 tp53 twice	aged aging amyloid antioxidant app cognition cognitive creb culprit decline defense detoxifying double dtg enhancing h2o2 hydrogen impairment importance key maintaining mice mitochondrial old peroxide peroxiredoxin tg transgenic wild
Tagcloud (Difference) ?		braf cure epha3 exons flt3 glioblastoma glioblastomas gliomagenesis hgg idh1 idh2 mapping mining mutated mutational nras offer opportunities pi3k pik3ca pten rational relapsing sequenced somatic synonymous tgfbr2 tp53 twice	aged aging amyloid antioxidant app cognition cognitive creb culprit decline defense detoxifying double dtg enhancing h2o2 hydrogen impairment importance key maintaining mice mitochondrial old peroxide peroxiredoxin tg transgenic wild
Tagcloud (Intersection) ?