GFER and BNIPL

Number of citations of the paper that reports this interaction (PMID 12681488)
8

Data Source:
HPRD (in vitro, in vivo, two hybrid)

		GFER	BNIPL
Gene Name		growth factor, augmenter of liver regeneration	BCL2/adenovirus E1B 19kD interacting protein like
Image			No pdb structure
Gene Ontology Annotations	Cellular Component	Extracellular Region Cytoplasm Mitochondrion Mitochondrial Intermembrane Space	Nucleus Cytosol
	Molecular Function	Protein Binding Growth Factor Activity Protein Disulfide Oxidoreductase Activity Thiol Oxidase Activity Flavin Adenine Dinucleotide Binding	Protein Binding Identical Protein Binding
	Biological Process	Protein Targeting To Mitochondrion Cellular Protein Metabolic Process Oxidation-reduction Process	Apoptotic Process Negative Regulation Of Cell Proliferation Regulation Of Growth Rate
Pathways		Mitochondrial protein import
Drugs
Diseases
GWAS			Chronic kidney disease ( 20383146)
Protein-Protein Interactions		7 interactors: ASCC2 BNIPL COPS2 COPS5 PLEKHF2 SMAD2 TXN	14 interactors: ARHGAP1 BAX BCL2 BCL2L1 BNIP2 CDC42 FKBP8 GFER MIF NME2 PXDN PYCR1 RECQL5 SNAPIN
Entrez ID		2671	149428
HPRD ID		02954	16557
Ensembl ID		ENSG00000127554	ENSG00000163141
Uniprot IDs		P55789	Q7Z465
PDB IDs		3MBG 3O55 3TK0 3U2L 3U2M 3U5S
Enriched GO Terms of Interacting Partners?		Cullin Deneddylation Protein Deneddylation Transcription, DNA-templated RNA Biosynthetic Process Protein Modification By Small Protein Removal Positive Regulation Of Nodal Signaling Pathway Involved In Determination Of Lateral Mesoderm Left/right Asymmetry RNA Metabolic Process Regulation Of Growth Rate Zygotic Specification Of Dorsal/ventral Axis Regulation Of Nodal Signaling Pathway Involved In Determination Of Lateral Mesoderm Left/right Asymmetry Regulation Of Transcription From RNA Polymerase II Promoter Gene Expression Negative Regulation Of Transcription From RNA Polymerase II Promoter Exosomal Secretion Cellular Macromolecule Biosynthetic Process Macromolecule Biosynthetic Process Transcription From RNA Polymerase II Promoter Positive Regulation Of Mesoderm Development Primary MiRNA Processing Negative Regulation Of Protein Export From Nucleus Regulation Of Nodal Signaling Pathway Common-partner SMAD Protein Phosphorylation Positive Regulation Of Activin Receptor Signaling Pathway Regulation Of Binding Regulation Of Transcription, DNA-templated Negative Regulation Of Transcription, DNA-templated Regulation Of Nucleic Acid-templated Transcription Regulation Of RNA Biosynthetic Process Negative Regulation Of Nucleic Acid-templated Transcription Negative Regulation Of RNA Biosynthetic Process Regulation Of RNA Metabolic Process Negative Regulation Of Hydrogen Peroxide-induced Cell Death SMAD Protein Complex Assembly Nucleobase-containing Compound Metabolic Process Regulation Of Hydrogen Peroxide-induced Cell Death Paraxial Mesoderm Morphogenesis Nodal Signaling Pathway Nucleobase-containing Small Molecule Interconversion Heterocycle Metabolic Process Cellular Aromatic Compound Metabolic Process Biosynthetic Process Negative Regulation Of Gene Expression Negative Regulation Of Biosynthetic Process Regulation Of Gene Expression Regulation Of Protein Import Into Nucleus, Translocation Regulation Of Nitrogen Compound Metabolic Process Cellular Nitrogen Compound Metabolic Process Production Of MiRNAs Involved In Gene Silencing By MiRNA Embryonic Foregut Morphogenesis Foregut Morphogenesis	Regulation Of Mitochondrial Membrane Potential Regulation Of Protein Heterodimerization Activity Negative Regulation Of Cell Death Regulation Of Cell Death Ovarian Follicle Development Positive Regulation Of Signal Transduction Ovulation Cycle Process Negative Regulation Of Apoptotic Process Regulation Of Peptidyl-serine Phosphorylation Negative Regulation Of Programmed Cell Death Female Gonad Development Regulation Of Apoptotic Process Ovulation Cycle Development Of Primary Female Sexual Characteristics Release Of Cytochrome C From Mitochondria Regulation Of Nitrogen Utilization Regulation Of Mitochondrial Membrane Permeability Regulation Of Membrane Permeability Regulation Of Protein Binding Mitochondrial Transport Regulation Of Intrinsic Apoptotic Signaling Pathway Extrinsic Apoptotic Signaling Pathway In Absence Of Ligand Response To Gamma Radiation Male Sex Differentiation Positive Regulation Of Intracellular Signal Transduction Neuron Apoptotic Process Regulation Of Signal Transduction Regulation Of Cell Development Positive Regulation Of Intrinsic Apoptotic Signaling Pathway Mitochondrial Membrane Organization Neuron Death Positive Regulation Of Cell Development Gonad Development Apoptotic Mitochondrial Changes Development Of Primary Sexual Characteristics Regulation Of Neuron Apoptotic Process Positive Regulation Of Intracellular Transport Germ Cell Development Regulation Of Signaling Negative Regulation Of Apoptotic Signaling Pathway Positive Regulation Of Peptidyl-serine Phosphorylation Regulation Of Binding Regulation Of Cellular Localization Regulation Of Extrinsic Apoptotic Signaling Pathway In Absence Of Ligand Regulation Of Membrane Potential Positive Regulation Of Muscle Cell Differentiation Regulation Of Neuron Death Negative Regulation Of Signal Transduction Sex Differentiation Intrinsic Apoptotic Signaling Pathway In Response To DNA Damage
Tagcloud ?		acting alr apoptotic augmenter behaviour caspase clusterin complementary encodes erv1 glioma hepatectomized integrity lethal modulates named neuroblastoma normoxic oxidase peroxide preserve ralr regenerating regeneration ros shed sulfhydryl supports t98g	allowing alters antagonization antagonize antiapoptotic bag1 bcl bcl2l13 becn1 bmf bnip1 bnip3 clu conditional considering erbb2 influences influencing master mcl members proapoptotic prognosis prototypic relevance remission substitute tegt whereby
Tagcloud (Difference) ?		acting alr apoptotic augmenter behaviour caspase clusterin complementary encodes erv1 glioma hepatectomized integrity lethal modulates named neuroblastoma normoxic oxidase peroxide preserve ralr regenerating regeneration ros shed sulfhydryl supports t98g	allowing alters antagonization antagonize antiapoptotic bag1 bcl bcl2l13 becn1 bmf bnip1 bnip3 clu conditional considering erbb2 influences influencing master mcl members proapoptotic prognosis prototypic relevance remission substitute tegt whereby
Tagcloud (Intersection) ?