TIAM2 and ANXA7

Number of citations of the paper that reports this interaction (PMID 21900206)
27

Data Source:
BioGRID (two hybrid)

		TIAM2	ANXA7
Gene Name		T-cell lymphoma invasion and metastasis 2	annexin A7
Image		No pdb structure	No pdb structure
Gene Ontology Annotations	Cellular Component	Cytosol Membrane Lamellipodium Filopodium Growth Cone Extracellular Vesicular Exosome	Nucleus Nuclear Envelope Endoplasmic Reticulum Membrane Cytosol Plasma Membrane Membrane Chromaffin Granule Membrane Extracellular Vesicular Exosome
	Molecular Function	Receptor Signaling Protein Activity Guanyl-nucleotide Exchange Factor Activity Rho Guanyl-nucleotide Exchange Factor Activity GTPase Activator Activity	Integrin Binding Calcium Ion Binding Protein Binding Calcium-dependent Phospholipid Binding Poly(A) RNA Binding Calcium-dependent Protein Binding
	Biological Process	Small GTPase Mediated Signal Transduction Positive Regulation Of Rho GTPase Activity Positive Regulation Of Apoptotic Process Cellular Lipid Metabolic Process Small Molecule Metabolic Process Neurotrophin TRK Receptor Signaling Pathway Regulation Of Small GTPase Mediated Signal Transduction Apoptotic Signaling Pathway	Cellular Calcium Ion Homeostasis Autophagy Hemostasis Cell Proliferation Regulation Of Cell Shape Response To Salt Stress Cellular Water Homeostasis Negative Regulation Of Gene Expression Response To Organic Cyclic Compound Epithelial Cell Differentiation Social Behavior Response To Calcium Ion Membrane Fusion
Pathways		Rho GTPase cycle PPARA activates gene expression Signaling by GPCR GPCR downstream signaling Signalling by NGF Fatty acid, triacylglycerol, and ketone body metabolism Metabolism of lipids and lipoproteins Cell death signalling via NRAGE, NRIF and NADE Signaling by Rho GTPases NRAGE signals death through JNK G alpha (12/13) signalling events p75 NTR receptor-mediated signalling Regulation of lipid metabolism by Peroxisome proliferator-activated receptor alpha (PPARalpha)
Drugs
Diseases
GWAS
Protein-Protein Interactions		9 interactors: ANXA7 DISC1 DNM2 H2AFX PARD3 SH3GL2 TK1 TNIK UFD1L	108 interactors: A1BG A2M ACTB ACTL6B ADAMTS10 ANGPT2 APC APLP1 ATP5B ATP6V1A ATXN3 BAG6 C14orf1 CCDC90B CCT7 CDK4 CELF3 CENPB CHGB CLEC3B COL11A2 COL4A2 COL4A5 COPS6 CPNE2 CPNE6 CPSF3L CRMP1 CSAD CTSB DDAH2 DMPK DOCK7 DVL1 DYNC1I1 EEF1A1 EXT2 F13A1 FAF1 FBN3 FGB FLAD1 GAPDH GBP2 GDF9 GNB2 GNB5 HADHB HMGXB3 HOXD8 INPP5K KLHL23 KMT2B LRIF1 MED31 MPPED1 MSH2 NGFR NMT2 NPRL2 OTUB1 PAAF1 PAX8 PDCD6 PDHB PKM PLD3 PRKACA PRKCA PRKCB PRKCG PRKG1 PSMB10 QARS RBBP4 RBM48 RPA1 RPL13 RPS2 S100A10 SDF4 SEMA5B SETDB1 SMPD1 SP110 SRC SRI SUMO3 TAF5L TIAM2 TLE1 TMEM108 TMSB4X TP53 TRMT2A TUBA1A TUBB2B TUBB3 UBE2D1 UCHL5 UNC119 USP4 VIM WDR18 WDR73 ZBTB16 ZNF135 ZNF431
Entrez ID		26230	310
HPRD ID		05273	01720
Ensembl ID		ENSG00000146426	ENSG00000138279
Uniprot IDs		B3KW11 E9PKT1 Q8IVF5	B2R657 P20073
PDB IDs
Enriched GO Terms of Interacting Partners?		Membrane Organization Anatomical Structure Development Developmental Process Generation Of Neurons System Development Neurogenesis Multicellular Organismal Development Regulation Of Neuron Projection Development Regulation Of Cellular Component Organization Fetal Process Involved In Parturition Organelle Localization Antigen Processing And Presentation Of Exogenous Peptide Antigen Via MHC Class II Post-Golgi Vesicle-mediated Transport Cell Differentiation Antigen Processing And Presentation Of Peptide Antigen Via MHC Class II Cell Projection Organization Regulation Of Cell Morphogenesis Regulation Of Cell Projection Organization Antigen Processing And Presentation Of Peptide Or Polysaccharide Antigen Via MHC Class II Nervous System Development Synaptic Vesicle Transport Negative Regulation Of Membrane Tubulation Skeletal Muscle Cell Proliferation Regulation Of Neuron Differentiation Cellular Localization Response To Stimulus Neuron Projection Morphogenesis Regulation Of Neurogenesis Cell Proliferation Response To Cortisol Apical Constriction Thymidine Metabolic Process Asymmetric Cell Division Establishment Of Vesicle Localization Vesicle Localization Deoxyribonucleoside Monophosphate Biosynthetic Process Neuron Projection Development Cell Projection Morphogenesis Antigen Processing And Presentation Of Peptide Antigen Regulation Of Cell Development Cell Part Morphogenesis Activation Of JNKK Activity Pyrimidine Nucleoside Salvage Pyrimidine-containing Compound Salvage Cellular Component Assembly Protein Localization Positive Regulation Of Myelination Golgi Vesicle Transport Neuron Development Wnt Signaling Pathway	Anatomical Structure Development Multicellular Organismal Development Developmental Process System Development Cellular Metabolic Process Metabolic Process Cellular Response To Organic Substance Platelet Activation Regulation Of Protein Metabolic Process Regulation Of Metabolic Process Cellular Response To Growth Factor Stimulus Regulation Of Cellular Protein Metabolic Process Blood Coagulation Response To Growth Factor Programmed Cell Death Hemostasis Negative Regulation Of Cellular Protein Metabolic Process Cell Death Catabolic Process Death Response To Organic Substance Apoptotic Process Histone H3-T6 Phosphorylation Regulation Of Apoptotic Process Nervous System Development Regulation Of Body Fluid Levels Negative Regulation Of Protein Metabolic Process Regulation Of Cell Death Negative Regulation Of Cellular Metabolic Process Regulation Of Protein Catabolic Process Cellular Protein Metabolic Process Regulation Of Proteolysis Mitotic Cell Cycle Process Negative Regulation Of Glucose Transport Organelle Organization Cell Activation Enzyme Linked Receptor Protein Signaling Pathway Regulation Of Catalytic Activity Cellular Process Regulation Of Cellular Response To Insulin Stimulus Wound Healing Cellular Response To Stimulus Regulation Of Proteasomal Protein Catabolic Process Gene Expression Protein Metabolic Process Mitotic Cell Cycle Organ Development Biosynthetic Process Cellular Nitrogen Compound Metabolic Process Chromosome Organization
Tagcloud ?			annexin anticancer antitumor chinese cytotoxic cytotoxicity decreasing depressed dramatically eecp ethanol exerted explored huvecs kappa mb mcf mda mitochondrial mu obviously p65 possess propolis ros umbilical upregulating vein
Tagcloud (Difference) ?			annexin anticancer antitumor chinese cytotoxic cytotoxicity decreasing depressed dramatically eecp ethanol exerted explored huvecs kappa mb mcf mda mitochondrial mu obviously p65 possess propolis ros umbilical upregulating vein
Tagcloud (Intersection) ?