GAP43 and RABEP1

Number of citations of the paper that reports this interaction (PMID 9742146)
16

Data Source:
HPRD (in vitro, in vivo)

		GAP43	RABEP1
Gene Name		growth associated protein 43	rabaptin, RAB GTPase binding effector protein 1
Image		No pdb structure
Gene Ontology Annotations	Cellular Component	Cytoplasm Plasma Membrane Postsynaptic Density Cell Junction Axon Filopodium Membrane Growth Cone Membrane	Endosome Early Endosome Endocytic Vesicle Intracellular Membrane-bounded Organelle Recycling Endosome
	Molecular Function	Protein Binding Calmodulin Binding	GTPase Activator Activity Protein Binding Growth Factor Activity Protein Homodimerization Activity
	Biological Process	Protein Kinase C-activating G-protein Coupled Receptor Signaling Pathway Response To Wounding Glial Cell Differentiation Axon Choice Point Recognition Regulation Of Growth Tissue Regeneration Cell Fate Commitment Regulation Of Filopodium Assembly Axon Development	Endocytosis Apoptotic Process Protein Transport Positive Regulation Of GTPase Activity Membrane Fusion
Pathways
Drugs
Diseases
GWAS		Breast size ( 22747683)
Protein-Protein Interactions		8 interactors: CALM1 CSNK2A1 ELAVL4 PLCD1 PRKCB PRKCD RABEP1 SPTAN1	22 interactors: AP1G1 AP1G2 ATXN7 CASP3 CCND1 GAP43 GGA1 GGA2 GGA3 HUNK ITSN1 ITSN2 RAB1A RAB33B RAB4A RAB5A RABGEF1 RGS17 TRIM26 TSC2 UBC YWHAG
Entrez ID		2596	9135
HPRD ID		01198	04684
Ensembl ID		ENSG00000172020	ENSG00000029725
Uniprot IDs		P17677 Q5U058	F5H355 Q15276
PDB IDs			1P4U 1TU3 1X79
Enriched GO Terms of Interacting Partners?		Vascular Endothelial Growth Factor Receptor Signaling Pathway Apoptotic Process Programmed Cell Death Cell Death Death Positive Regulation Of Protein Dephosphorylation Platelet Activation Negative Regulation Of Insulin Receptor Signaling Pathway Peptidyl-threonine Phosphorylation Positive Regulation Of Dephosphorylation Inositol Phosphate Metabolic Process Activation Of Phospholipase C Activity Positive Regulation Of Phospholipase C Activity Positive Regulation Of Transporter Activity Cellular Component Disassembly Involved In Execution Phase Of Apoptosis Regulation Of Insulin Receptor Signaling Pathway Immune Response-regulating Cell Surface Receptor Signaling Pathway Negative Regulation Of Actin Filament Polymerization Execution Phase Of Apoptosis Positive Regulation Of Phospholipase Activity Blood Coagulation Hemostasis Regulation Of Cellular Response To Insulin Stimulus Positive Regulation Of Phospholipid Scramblase Activity Positive Regulation Of Glucosylceramide Catabolic Process Positive Regulation Of Sphingomyelin Catabolic Process Negative Regulation Of Protein Polymerization Regulation Of Phospholipase Activity Positive Regulation Of Lipase Activity Immune Response-regulating Signaling Pathway Positive Regulation Of Phospholipid Catabolic Process Histone H3-T6 Phosphorylation Regulation Of Body Fluid Levels Regulation Of Dephosphorylation Wound Healing Negative Regulation Of Protein Complex Assembly Interleukin-10 Production Phosphate-containing Compound Metabolic Process Transmembrane Receptor Protein Tyrosine Kinase Signaling Pathway B Cell Activation Cell Activation Response To Wounding Negative Regulation Of Cytoskeleton Organization Epidermal Growth Factor Receptor Signaling Pathway Negative Regulation Of Filopodium Assembly Positive Regulation Of Cyclic-nucleotide Phosphodiesterase Activity Fibroblast Growth Factor Receptor Signaling Pathway ERBB Signaling Pathway Regulation Of Actin Filament Polymerization Interleukin-12 Production	Intracellular Protein Transport Intracellular Transport Establishment Of Localization In Cell Cellular Protein Localization Protein Transport Vesicle-mediated Transport Establishment Of Protein Localization Cellular Localization Protein Localization Transport Rab Protein Signal Transduction Regulation Of Vesicle-mediated Transport Membrane Organization Positive Regulation Of Metabolic Process Regulation Of Exocytosis Regulation Of Phosphorylation Intracellular Signal Transduction Endocytosis Regulation Of Endocytosis Negative Regulation Of Phosphorylation Regulation Of Phosphorus Metabolic Process Positive Regulation Of Catalytic Activity Neurotrophin TRK Receptor Signaling Pathway Ras Protein Signal Transduction Neurotrophin Signaling Pathway Regulation Of Protein Metabolic Process Regulation Of Catalytic Activity Negative Regulation Of Transferase Activity Signal Transduction Negative Regulation Of Protein Phosphorylation Regulation Of Signaling Regulation Of Cellular Component Organization Small GTPase Mediated Signal Transduction Virion Assembly Positive Regulation Of Hydrolase Activity Apoptotic Signaling Pathway Negative Regulation Of Protein Serine/threonine Kinase Activity Regulation Of Protein Phosphorylation Negative Regulation Of Signal Transduction Cytoplasmic Transport Signaling Regulation Of Metabolic Process Positive Regulation Of GTPase Activity Regulation Of Signal Transduction Cellular Response To Stimulus Cell Communication Regulation Of Protein Kinase Activity Negative Regulation Of Signaling Negative Regulation Of Exocytosis Protein Targeting
Tagcloud ?			adpkd arl3 autosomal cilia ciliary ciliopathies cleaved couples gga1 golgi gps localize milieu module must pc1 pc2 polycystic polycystin proper proteolytically reach sense tgn traffic trafficking transmembrane tubular whereby
Tagcloud (Difference) ?			adpkd arl3 autosomal cilia ciliary ciliopathies cleaved couples gga1 golgi gps localize milieu module must pc1 pc2 polycystic polycystin proper proteolytically reach sense tgn traffic trafficking transmembrane tubular whereby
Tagcloud (Intersection) ?