BAMBI and SOX30

Number of citations of the paper that reports this interaction (PMID 16189514)
699

Data Source:
HPRD (two hybrid)

		BAMBI	SOX30
Gene Name		BMP and activin membrane-bound inhibitor	SRY (sex determining region Y)-box 30
Image		No pdb structure	No pdb structure
Gene Ontology Annotations	Cellular Component	Cytoplasm Plasma Membrane Integral Component Of Membrane	Nucleus
	Molecular Function	Frizzled Binding Type II Transforming Growth Factor Beta Receptor Binding	Sequence-specific DNA Binding RNA Polymerase II Transcription Factor Activity Sequence-specific DNA Binding
	Biological Process	Transforming Growth Factor Beta Receptor Signaling Pathway Positive Regulation Of Cell Proliferation Regulation Of Cell Shape Positive Regulation Of Epithelial To Mesenchymal Transition Cell Migration Negative Regulation Of Transforming Growth Factor Beta Receptor Signaling Pathway Positive Regulation Of Protein Binding Positive Regulation Of Catenin Import Into Nucleus Positive Regulation Of Transcription, DNA-templated Positive Regulation Of Canonical Wnt Signaling Pathway	Transcription, DNA-templated Regulation Of Transcription, DNA-templated Regulation Of Transcription From RNA Polymerase II Promoter Transcription From RNA Polymerase II Promoter Spermatogenesis Response To Corticosteroid
Pathways		Loss of Function of TGFBR2 in Cancer TGFBR2 MSI Frameshift Mutants in Cancer SMAD2/3 Phosphorylation Motif Mutants in Cancer Loss of Function of SMAD2/3 in Cancer TGFBR2 Kinase Domain Mutants in Cancer Loss of Function of SMAD4 in Cancer Downregulation of TGF-beta receptor signaling SMAD2/3 MH2 Domain Mutants in Cancer TGFBR1 KD Mutants in Cancer TGF-beta receptor signaling activates SMADs TGFBR1 LBD Mutants in Cancer Loss of Function of TGFBR1 in Cancer Signaling by TGF-beta Receptor Complex Signaling by TGF-beta Receptor Complex in Cancer SMAD4 MH2 Domain Mutants in Cancer
Drugs
Diseases
GWAS		Preeclampsia ( 23551011)
Protein-Protein Interactions		8 interactors: ACVR1 ACVR1B ACVRL1 BMPR1A BMPR1B SEP15 SOX30 TGFBR1	16 interactors: AHCYL1 BAMBI BRCA1 C6orf165 CUL5 DCAF4 DDX56 FBXO38 FLI1 GNAI3 GP2 KIFC3 NME1 NUDT3 PAXIP1 TRAF2
Entrez ID		25805	11063
HPRD ID		05117	09461
Ensembl ID		ENSG00000095739	ENSG00000039600
Uniprot IDs		Q13145	B4DXW7 O94993
PDB IDs
Enriched GO Terms of Interacting Partners?		Positive Regulation Of Pathway-restricted SMAD Protein Phosphorylation Regulation Of Pathway-restricted SMAD Protein Phosphorylation Transmembrane Receptor Protein Serine/threonine Kinase Signaling Pathway Signal Transduction By Phosphorylation Activin Receptor Signaling Pathway BMP Signaling Pathway Enzyme Linked Receptor Protein Signaling Pathway Transforming Growth Factor Beta Receptor Signaling Pathway Cellular Response To Transforming Growth Factor Beta Stimulus In Utero Embryonic Development Response To Transforming Growth Factor Beta Positive Regulation Of Bone Mineralization Positive Regulation Of Biomineral Tissue Development Peptidyl-threonine Phosphorylation Positive Regulation Of Signal Transduction Protein Phosphorylation Reproductive Process Developmental Process Involved In Reproduction Positive Regulation Of Protein Phosphorylation Sex Differentiation Regulation Of Bone Mineralization Positive Regulation Of Osteoblast Differentiation Chordate Embryonic Development Embryo Development Ending In Birth Or Egg Hatching Regulation Of Cell Differentiation Regulation Of Cartilage Development Positive Regulation Of Cell Differentiation Positive Regulation Of Phosphorylation Tissue Development Positive Regulation Of Ossification Positive Regulation Of Protein Modification Process Regulation Of Transcription From RNA Polymerase II Promoter Phosphorylation Intracellular Signal Transduction Mesenchymal Cell Development Pathway-restricted SMAD Protein Phosphorylation Regulation Of Osteoblast Differentiation Positive Regulation Of SMAD Protein Import Into Nucleus Regulation Of Protein Phosphorylation Mesenchymal Cell Differentiation Pattern Specification Process Positive Regulation Of Cellular Protein Metabolic Process Regulation Of SMAD Protein Import Into Nucleus Pharyngeal System Development Embryo Development Positive Regulation Of Epithelial Cell Proliferation Single Organism Reproductive Process Positive Regulation Of Protein Metabolic Process Cellular Response To Growth Factor Stimulus Regulation Of Activin Receptor Signaling Pathway	Positive Regulation Of Histone H3-K4 Methylation Positive Regulation Of Binding Positive Regulation Of Histone Acetylation Regulation Of Histone H3-K4 Methylation Positive Regulation Of Peptidyl-lysine Acetylation Positive Regulation Of Protein Acetylation Positive Regulation Of Histone Methylation Protein Ubiquitination Protein Autoubiquitination Regulation Of Histone Acetylation Protein Modification By Small Protein Conjugation Regulation Of Histone Methylation Regulation Of Binding Positive Regulation Of Histone H4-K20 Methylation Positive Regulation Of Histone H3-K36 Methylation Antigen Transcytosis By M Cells In Mucosal-associated Lymphoid Tissue Positive Regulation Of Histone H4-K16 Acetylation Diphosphoinositol Polyphosphate Catabolic Process Diadenosine Polyphosphate Catabolic Process Positive Regulation Of Protein Binding Positive Regulation Of Histone Modification DNA Damage Response, Signal Transduction By P53 Class Mediator Positive Regulation Of Histone H3-K9 Acetylation Signal Transduction In Response To DNA Damage Cellular Response To Tumor Necrosis Factor Zonula Adherens Maintenance Positive Regulation Of Histone H4 Acetylation Negative Regulation Of Histone H3-K4 Methylation Signal Transduction By P53 Class Mediator Regulation Of Histone Modification Response To Tumor Necrosis Factor Positive Regulation Of Protein Ubiquitination S-adenosylmethionine Cycle Cellular Response To Indole-3-methanol Response To Ionizing Radiation Regulation Of Protein Binding Positive Regulation Of DNA Metabolic Process Negative Regulation Of Centriole Replication Positive Regulation Of Adaptive Immune Response Dosage Compensation By Inactivation Of X Chromosome Negative Regulation Of Glial Cell Apoptotic Process Protein Polyubiquitination Protein K6-linked Ubiquitination Chorion Development Regulation Of Histone H3-K9 Acetylation Negative Regulation Of Histone H3-K9 Methylation Positive Regulation Of Histone H3-K9 Methylation Dosage Compensation Intrinsic Apoptotic Signaling Pathway Nucleobase-containing Small Molecule Metabolic Process
Tagcloud ?		95th bavaria bavarian breastfed chlorophenyl dde dibenzofurans dichloro hexachlorobenzene hrms mugl musks ngg ngkg ops organochlorine pcbs pcdds pcdfs perfluorinated perfluorooctane pfcs polychlorinated sulfonate tdi teq1998 teq1998g tolerable who1998	activating advance antitumorigenic attenuates blockade box cactttg doi ectopic harboring hypermethylated hypermethylation indeed lung methylated onc oncogene online peri preferentially publication represses silence silenced sry tumoral unexplored unmethylated
Tagcloud (Difference) ?		95th bavaria bavarian breastfed chlorophenyl dde dibenzofurans dichloro hexachlorobenzene hrms mugl musks ngg ngkg ops organochlorine pcbs pcdds pcdfs perfluorinated perfluorooctane pfcs polychlorinated sulfonate tdi teq1998 teq1998g tolerable who1998	activating advance antitumorigenic attenuates blockade box cactttg doi ectopic harboring hypermethylated hypermethylation indeed lung methylated onc oncogene online peri preferentially publication represses silence silenced sry tumoral unexplored unmethylated
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